日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The late-onset Alzheimer's disease risk factor RHBDF2 is a modifier of microglial TREM2 proteolysis

晚发性阿尔茨海默病风险因子RHBDF2是小胶质细胞TREM2蛋白水解的调节因子。

Georg Jocher ,Gozde Ozcelik ,Stephan A Müller ,Hung-En Hsia ,Miranda Lastra Osua ,Laura I Hofmann ,Marlene Aßfalg ,Lina Dinkel ,Xiao Feng ,Kai Schlepckow ,Michael Willem ,Christian Haass ,Sabina Tahirovic ,Carl P Blobel ,Stefan F Lichtenthaler

The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling

阿尔茨海默病相关蛋白酶 BACE2 可裂解 VEGFR3 并调节其信号传导

Andree Schmidt, Brian Hrupka, Frauke van Bebber, Sanjay Sunil Kumar, Xiao Feng, Sarah K Tschirner, Marlene Aßfalg, Stephan A Müller, Laura Sophie Hilger, Laura I Hofmann, Martina Pigoni, Georg Jocher, Iryna Voytyuk, Emily L Self, Mana Ito, Kana Hyakkoku, Akimasa Yoshimura, Naotaka Horiguchi, Regina

Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase

γ-分泌酶介导的膜内蛋白水解过程中,底物跨膜结构域N端和C端片段的协同作用

Nadine T Werner # ,Philipp Högel # ,Gökhan Güner # ,Walter Stelzer ,Manfred Wozny ,Marlene Aßfalg ,Stefan F Lichtenthaler ,Harald Steiner ,Dieter Langosch

Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity

蛋白水解产生的可溶性 Tweak 受体 Fn14 是 γ-分泌酶活性的血液生物标志物

Gökhan Güner, Marlene Aßfalg, Kai Zhao, Tobias Dreyer, Shibojyoti Lahiri, Yun Lo, Bianca Ionela Slivinschi, Axel Imhof, Georg Jocher, Laura Strohm, Christian Behrends, Dieter Langosch, Holger Bronger, Christopher Nimsky, Jörg W Bartsch, Stanley R Riddell, Harald Steiner, Stefan F Lichtenthaler

[DGPPN pilot study on the implementation of the S3 guideline "Prevention of coercion: prevention and therapy of aggressive behavior in adults"]

[DGPPN关于实施S3指南“预防胁迫:预防和治疗成人攻击性行为”的试点研究]

Bechdolf, Andreas; Bühling-Schindowski, Felix; Weinmann, Stefan; Baumgardt, Johanna; Kampmann, Marie; Sauter, Dorothea; Jaeger, Susanne; Walter, Gernot; Mayer, Michael; Löhr, Michael; Schulz, Michael; Gather, Jakov; Ketelsen, Regina; Aßfalg, Ralf; Cole, Celline; Vandamme, Angelika; Mahler, Lieselotte; Hirsch, Sophie; Steinert, Tilman

[Implementation of discharge management in the surgical department of a university hospital: exploratory analysis of costs, length of stay, and patient satisfaction]

[大学医院外科出院管理实施情况:成本、住院时间和患者满意度的探索性分析]

Aßfalg, Volker; Hassiotis, Sophia; Radonjic, Marion; Göcmez, Sarah; Friess, Helmut; Frank, Elke; Königstorfer, Jörg

The Impact of Mitochondrial Dysfunction on Dopaminergic Neurons in the Olfactory Bulb and Odor Detection

线粒体功能障碍对嗅球多巴胺能神经元及气味检测的影响

Paß, Thomas; Aßfalg, Marlene; Tolve, Marianna; Blaess, Sandra; Rothermel, Markus; Wiesner, Rudolf J; Ricke, Konrad M

Prediction and Reduction of the Aggregation of Monoclonal Antibodies

单克隆抗体聚集的预测和减少

Rob van der Kant, Anne R Karow-Zwick, Joost Van Durme, Michaela Blech, Rodrigo Gallardo, Daniel Seeliger, Kerstin Aßfalg, Pieter Baatsen, Griet Compernolle, Ann Gils, Joey M Studts, Patrick Schulz, Patrick Garidel, Joost Schymkowitz, Frederic Rousseau

Correction: A Systematic Proteomic Study of Irradiated DNA Repair Deficient Nbn-Mice

更正:对受辐射DNA修复缺陷型Nbn小鼠进行系统蛋白质组学研究

Katsounas, Antonios; Schalk, Enrico; Borchers, Moritz; Aßfalg, Anika; Melchers, Anna; Stöckl, Lars; Radszewski, Janina; Anders, Marco; Krenzlin, Harald; Kalischke, Candy; Scholz, Regina; Jordan, Andreas; Nebrich, Grit; Klose, Joachim; Sperling, Karl; Digweed, Martin; Demuth, Ilja