文献库，生知库 | 链接生命科学的每一步

日期影响因子

A microRNA expression signature in infant t(4;11) KMT2A::AFF1+ BCP-ALL uncovers novel therapeutic targets

婴儿t(4;11) KMT2A::AFF1+ BCP-ALL中的microRNA表达特征揭示了新的治疗靶点

期刊:Hemasphere

影响因子:14.6

doi:10.1002/hem3.70353

Malouf, Camille; Duguid, Alasdair; Vrenken, Kirsten S; Leah, Tom; Medhi, Ragini; Camiolo, Giuseppina; Nitsche, Leslie; Jakobczyk, Hélène; Kotecha, Rishi S; Anderson, Richard A; Barrett, Neil A; Smith, Owen P; Stam, Ronald W; Ottersbach, Katrin

发表日期：2026

文献求助收藏

A microRNA expression signature in infant t(4;11) KMT2A::AFF1+ BCP‐ALL uncovers novel therapeutic targets

婴儿 t(4;11) KMT2A::AFF1+ BCP-ALL 中的 microRNA 表达特征揭示了新的治疗靶点

期刊:Hemasphere

影响因子:14.6

doi:10.1097/HS9.0000000000000809

Papadopoulou, Anastasia; Alvanou, Maria; Karavalakis, George; Tzannou, Ifigeneia; Yannaki, Evangelia; Malouf, Camille; Duguid, Alasdair; Vrenken, Kirsten S; Leah, Tom; Medhi, Ragini; Camiolo, Giuseppina; Nitsche, Leslie; Jakobczyk, Hélène; Kotecha, Rishi S; Anderson, Richard A; Barrett, Neil A; Smith, Owen P; Stam, Ronald W; Ottersbach, Katrin

发表日期：2026

文献求助收藏

Structural insights into WRN helicase reveal conformational states and opportunities for MSI-H cancer drug discovery

对WRN解旋酶的结构解析揭示了其构象状态，并为MSI-H癌症药物研发提供了契机。

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-026-09584-0

Fletcher, Catherine T; Mornement, Abigail A; Barrett, Charlotte; Canning, Peter; Rucktooa, Prakash; Huber, Sophie; Cooper, Christopher D O; Scully, Conor C G; Doré, Andrew S; Rohle, Daniel; Smith, Geoffrey M T; Skerratt, Sarah E; Kennedy, Amanda J

多发性硬化症

发表日期：2026

文献求助收藏

Cost-Effectiveness and Health Equity Improvements From Excluding Sugar-Sweetened Beverages From the Supplemental Nutrition Assistance Program

将含糖饮料排除在补充营养援助计划之外，可提高成本效益并改善健康公平性。

期刊:American Journal of Preventive Medicine

影响因子:4.5

doi:10.1016/j.amepre.2025.108082

Musicus, Aviva A; Barrett, Jessica L; McCulloch, Stephanie M; Long, Michael W; Ward, Zachary J; Cradock, Angie L; Bleich, Sara N; Gortmaker, Steven L

发表日期：2026

文献求助收藏

Cysteinyl Leukotrienes in Allergic Inflammation

半胱氨酰白三烯在过敏性炎症中的作用

期刊:Annual Review of Pathology-Mechanisms of Disease

影响因子:34.5

doi:10.1146/annurev-pathmechdis-111523-023509

Lee, Minkyu; Boyce, Joshua A; Barrett, Nora A

Immunology/Inflammation

发表日期：2025

文献求助收藏

Mindfulness-based cognitive therapy versus treatment as usual after non-remission with NHS Talking Therapies high-intensity psychological therapy for depression: a UK-based clinical effectiveness and cost-effectiveness randomised, controlled, superiority trial

在英国开展的一项基于英国的随机对照、临床有效性和成本效益随机对照优效性试验中，比较了正念认知疗法与常规治疗在接受NHS高强度心理疗法治疗抑郁症未缓解后的疗效。

期刊:Lancet Psychiatry

影响因子:24.8

doi:10.1016/S2215-0366(25)00105-1

Barnhofer, Thorsten; Dunn, Barnaby D; Strauss, Clara; Ruths, Florian A; Barrett, Barbara; Ryan, Mary; Ladwa, Asha; Stafford, Frances; Fichera, Roberta; Baber, Hannah; McGuinness, Ailis; Metcalfe, Isabella; Kan, Daniel K Y; Pooley, Joanna; Harding, Delilah; Tassie, Emma; Carson, James; Rhodes, Shelley; Young, Allan H; Connors, James; Warren, Fiona C

发表日期：2025

文献求助收藏

IKAROS levels are associated with antigen escape in CD19- and CD22-targeted therapies for B-cell malignancies

IKAROS 水平与 CD19 和 CD22 靶向治疗 B 细胞恶性肿瘤中的抗原逃逸相关。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-58868-2

Domizi, Pablo; Sarno, Jolanda; Jager, Astraea; Merchant, Milton; Pacheco, Kaithlen Zen B; Yamada-Hunter, Sean A; Rotiroti, Maria Caterina; Liu, Yuxuan; Baskar, Reema; Reynolds, Warren D; Sworder, Brian J; Sahaf, Bita; Bendall, Sean C; Mullighan, Charles G; Alizadeh, Ash A; Leahy, Allison B; Myers, Regina M; Yates, Bonnie; Wang, Hao-Wei; Shah, Nirali N; Majzner, Robbie G; Mackall, Crystal L; Grupp, Stephan A; Barrett, David M; Sotillo, Elena; Davis, Kara L

细胞生物学

发表日期：2025

文献求助收藏

Spiral phyllotaxis predicts left-right asymmetric growth and style deflection in mirror-image flowers of Cyanella alba

螺旋叶序预测了白花蓝蓟镜像花朵的左右不对称生长和花柱偏转。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-58803-5

Robertson, Caroline; Xue, Haoran; Saltini, Marco; Fairnie, Alice L M; Lang, Dirk; Kerstens, Merijn H L; Willemsen, Viola; Ingle, Robert A; Barrett, Spencer C H; Deinum, Eva E; Illing, Nicola; Lenhard, Michael

发表日期：2025

文献求助收藏

Drug-Gene Interactions and Clinical Outcomes After Vascular Surgery in the Million Veteran Program

百万退伍军人计划中血管手术后的药物-基因相互作用和临床结果

期刊:Jama Surgery

影响因子:14.9

doi:10.1001/jamasurg.2025.1503

Tuteja, Sony; O'Brien, William J; Ferraro, Jeffrey P; Damrauer, Scott M; Itani, Kamal M F; Voight, Benjamin F; Teerlink, Craig C; Lynch, Julie A; DuVall, Scott L; Strebel, Timothy; Kim, Michael J; Wilson, Mark A; Barrett, Thomas W

发表日期：2025

文献求助收藏

Acute experimental colitis in 5xFAD Alzheimer's disease mice leads to enhanced monocyte infiltration into the brain accompanied by reduced β-amyloid deposition

在5xFAD阿尔茨海默病小鼠中，急性实验性结肠炎会导致单核细胞向大脑的浸润增强，同时伴有β-淀粉样蛋白沉积减少。

期刊:Alzheimers & Dementia

影响因子:13

doi:10.1002/alz.70292

Nanda K Navalpur Shanmugam ，Frank Zamudio ，Deepak K Vijaya Kumar ，Kianna A Barrett ，Ryan VanDoren ，Meng Chen ，Olivia M Barr ，Sara Watson ，Chih-Chung Jerry Lin ，William A Eimer ，Mehdi Jorfi ，Se Hoon Choi ，Robert D Moir ，Rudolph E Tanzi

细胞生物学

阿尔茨海默症

发表日期：2025

文献求助收藏