Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function
开发 MAPT S305 突变模型,该模型表现出 4R tau 表达升高,导致神经元和星形胶质细胞功能改变
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doi:10.1101/2023.06.02.543224
K R Bowles, D A Pugh, C Pedicone, L Oja, S A Weitzman, Y Liu, J L Chen, M D Disney, A M Goate