JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans
JNJ-77242113 是一种针对 IL-23 受体的高效选择性肽,在大鼠和人类口服后可产生强大的 IL-23 通路抑制作用
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-67371-5
Anne M Fourie, Xiaoli Cheng, Leon Chang, Carrie Greving, Xinyi Li, Beverly Knight, David Polidori, Aaron Patrick, Trpta Bains, Ruth Steele, Samantha J Allen, Raymond J Patch, Chengzao Sun, Sandeep Somani, Ashok Bhandari, David Liu, Keith Huie, Shu Li, Michael A Rodriguez, Xiaohua Xue, Arun Kannan, T