日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML

全基因组 CRISPR/Cas9 筛选确定与儿童 AML 临床结果相关的依托泊苷反应调节剂

Nam H K Nguyen, Roya Rafiee, Abderrahmane Tagmount, Amin Sobh, Alex Loguinov, Angelica K de Jesus Sosa, Abdelrahman H Elsayed, Mohammed Gbadamosi, Nathan Seligson, Christopher R Cogle, Jeffery Rubnitz, Raul Ribeiro, James Downing, Xueyuan Cao, Stanley B Pounds, Christopher D Vulpe, Jatinder K Lamba

Genome-scale CRISPR screens identify host factors that promote human coronavirus infection

基因组规模的 CRISPR 筛选可识别促进人类冠状病毒感染的宿主因素

Marco Grodzki, Andrew P Bluhm, Moritz Schaefer, Abderrahmane Tagmount, Max Russo, Amin Sobh, Roya Rafiee, Chris D Vulpe, Stephanie M Karst, Michael H Norris

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216

使用 BCL-XL 特异性降解剂 DT2216 克服胰腺癌的吉西他滨耐药性

Dinesh Thummuri #, Sajid Khan #, Patrick W Underwood #, Peiyi Zhang, Janet Wiegand, Xuan Zhang, Vivekananda Budamagunta, Amin Sobh, Abderrahmane Tagmount, Alexander Loguinov, Andrea N Riner, Ashwin S Akki, Elizabeth Williamson, Robert Hromas, Christopher D Vulpe, Guangrong Zheng, Jose G Trevino, Dao

Genome-wide CRISPR Screen Reveal Targets of Chiral Gold(I) Anticancer Compound in Mammalian Cells

全基因组 CRISPR 筛选揭示手性金(I)抗癌化合物在哺乳动物细胞中的靶点

Jong Hyun Kim, Samuel Ofori, Abderrahmane Tagmount, Chris D Vulpe, Samuel G Awuah

Functional Pathway Identification With CRISPR/Cas9 Genome-wide Gene Disruption in Human Dopaminergic Neuronal Cells Following Chronic Treatment With Dieldrin

长期接受狄氏剂治疗后,利用 CRISPR/Cas9 全基因组基因破坏技术识别人类多巴胺能神经元细胞的功能通路

Max Russo, Amin Sobh, Ping Zhang, Alex Loguinov, Abderrahmane Tagmount, Chris D Vulpe, Bin Liu

CXL146, a Novel 4 H-Chromene Derivative, Targets GRP78 to Selectively Eliminate Multidrug-Resistant Cancer Cells

CXL146 是一种新型 4 H-色烯衍生物,靶向 GRP78 以选择性消除多药耐药癌细胞

Tengfei Bian, Abderrahmane Tagmount, Christopher Vulpe, Kavitha Chandagirikoppal Vijendra, Chengguo Xing

Genome-Wide CRISPR Screening Identifies the Tumor Suppressor Candidate OVCA2 As a Determinant of Tolerance to Acetaldehyde

全基因组 CRISPR 筛选鉴定出肿瘤抑制候选基因 OVCA2,该基因是乙醛耐受性的决定因素。

Amin Sobh ,Alex Loguinov ,Alessia Stornetta ,Silvia Balbo ,Abderrahmane Tagmount ,Luoping Zhang ,Chris D Vulpe

Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells

乳腺癌细胞中的对羟基苯甲酸酯和人表皮生长因子受体配体相互作用

Shawn Pan, Chaoshen Yuan, Abderrahmane Tagmount, Ruthann A Rudel, Janet M Ackerman, Paul Yaswen, Chris D Vulpe, Dale C Leitman