Abernathy-Close相关文献与解析，生知库 | 链接生命科学的每一步

Topical Mupirocin Treatment Reduces Interferon and Myeloid Signatures in Cutaneous Lupus Erythematous Lesions Through Targeting of Staphylococcus Species

局部应用莫匹罗星治疗通过靶向葡萄球菌属细菌，减少皮肤红斑狼疮病变中的干扰素和髓系特征

Abernathy-Close, Lisa; Mears, Joseph; Billi, Allison C; Sirobhushanam, Sirisha; Berthier, Celine; Lu, Annie; Zhang, Zeran; Hurst, Amy; Gudjonsson, Johann E; Kahlenberg, J Michelle

微生物学

Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease

狼疮真皮成纤维细胞具有促炎特性，并在瘢痕性皮肤病中表现出促纤维化表型。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.173437

Shoffner-Beck, Suzanne K; Abernathy-Close, Lisa; Lazar, Stephanie; Ma, Feiyang; Gharaee-Kermani, Mehrnaz; Hurst, Amy; Dobry, Craig; Pandian, Deepika; Wasikowski, Rachael; Victory, Amanda; Arnold, Kelly; Gudjonsson, Johann E; Tsoi, Lam C; Kahlenberg, J Michelle

Intestinal Inflammation Reversibly Alters the Microbiota to Drive Susceptibility to Clostridioides difficile Colonization in a Mouse Model of Colitis

在结肠炎小鼠模型中，肠道炎症可逆性地改变肠道菌群，从而增加艰难梭菌定植的易感性。

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.01904-22

Barron, Madeline R; Sovacool, Kelly L; Abernathy-Close, Lisa; Vendrov, Kimberly C; Standke, Alexandra K; Bergin, Ingrid L; Schloss, Patrick D; Young, Vincent B

炎症

肠炎

炎症/感染

Immunology/Inflammation

Distinct stimulus-dependent neutrophil dynamics revealed by real-time imaging of intestinal mucosa after acute injury

急性损伤后肠粘膜实时成像揭示独特的刺激依赖性中性粒细胞动力学

期刊:PNAS Nexus

影响因子:2.2

doi:10.1093/pnasnexus/pgac249

Veronica Azcutia, Matthias Kelm, Seonyoung Kim, Anny-Claude Luissint, Sven Flemming, Lisa Abernathy-Close, Vincent B Young, Asma Nusrat, Mark J Miller, Charles A Parkos

B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity

B细胞特征可区分皮肤红斑狼疮亚型及系统性疾病活动性。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2021.775353

Abernathy-Close, Lisa; Lazar, Stephanie; Stannard, Jasmine; Tsoi, Lam C; Eddy, Sean; Rizvi, Syed M; Yee, Christine M; Myers, Emily M; Namas, Rajaie; Lowe, Lori; Reed, Tamra J; Wen, Fei; Gudjonsson, Johann E; Kahlenberg, J Michelle; Berthier, Celine C

Intestinal Inflammation and Altered Gut Microbiota Associated with Inflammatory Bowel Disease Render Mice Susceptible to Clostridioides difficile Colonization and Infection

与炎症性肠病相关的肠道炎症和肠道菌群改变使小鼠易受艰难梭菌定植和感染

期刊:mBio

影响因子:5.1

doi:10.1128/mBio.02733-20

Lisa Abernathy-Close, Madeline R Barron, James M George, Michael G Dieterle, Kimberly C Vendrov, Ingrid L Bergin, Vincent B Young

Systemic Inflammatory Mediators Are Effective Biomarkers for Predicting Adverse Outcomes in Clostridioides difficile Infection

系统性炎症介质是预测艰难梭菌感染不良预后的有效生物标志物

期刊:mBio

影响因子:4.7

doi:10.1128/mBio.00180-20

Dieterle, Michael G; Putler, Rosemary; Perry, D Alexander; Menon, Anitha; Abernathy-Close, Lisa; Perlman, Naomi S; Penkevich, Aline; Standke, Alex; Keidan, Micah; Vendrov, Kimberly C; Bergin, Ingrid L; Young, Vincent B; Rao, Krishna

Aging Dampens the Intestinal Innate Immune Response during Severe Clostridioides difficile Infection and Is Associated with Altered Cytokine Levels and Granulocyte Mobilization

衰老会抑制艰难梭菌重症感染期间的肠道固有免疫反应，并与细胞因子水平改变和粒细胞动员有关。

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/IAI.00960-19

Abernathy-Close, Lisa; Dieterle, Michael G; Vendrov, Kimberly C; Bergin, Ingrid L; Rao, Krishna; Young, Vincent B

The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis

JAK抑制剂鲁索替尼可减轻ILC3非依赖性先天免疫性结肠炎模型中的炎症。

期刊:Mucosal Immunology

影响因子:7.6

doi:10.1038/s41385-018-0051-2

Overstreet, A M; LaTorre, D L; Abernathy-Close, L; Murphy, S F; Rhee, L; Boger, A M; Adlaka, K R; Iverson, A M; Bakke, D S; Weber, C R; Boone, D L

Cutaneous lupus erythematosus - from pathogenesis to targeted therapy

皮肤红斑狼疮——从发病机制到靶向治疗

Topical Mupirocin Treatment Reduces Interferon and Myeloid Signatures in Cutaneous Lupus Erythematous Lesions Through Targeting of Staphylococcus Species

局部应用莫匹罗星治疗通过靶向葡萄球菌属细菌，减少皮肤红斑狼疮病变中的干扰素和髓系特征

Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease

狼疮真皮成纤维细胞具有促炎特性，并在瘢痕性皮肤病中表现出促纤维化表型。

Intestinal Inflammation Reversibly Alters the Microbiota to Drive Susceptibility to Clostridioides difficile Colonization in a Mouse Model of Colitis

在结肠炎小鼠模型中，肠道炎症可逆性地改变肠道菌群，从而增加艰难梭菌定植的易感性。

Distinct stimulus-dependent neutrophil dynamics revealed by real-time imaging of intestinal mucosa after acute injury

急性损伤后肠粘膜实时成像揭示独特的刺激依赖性中性粒细胞动力学

B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity

B细胞特征可区分皮肤红斑狼疮亚型及系统性疾病活动性。

Intestinal Inflammation and Altered Gut Microbiota Associated with Inflammatory Bowel Disease Render Mice Susceptible to Clostridioides difficile Colonization and Infection

与炎症性肠病相关的肠道炎症和肠道菌群改变使小鼠易受艰难梭菌定植和感染

Systemic Inflammatory Mediators Are Effective Biomarkers for Predicting Adverse Outcomes in Clostridioides difficile Infection

系统性炎症介质是预测艰难梭菌感染不良预后的有效生物标志物

Aging Dampens the Intestinal Innate Immune Response during Severe Clostridioides difficile Infection and Is Associated with Altered Cytokine Levels and Granulocyte Mobilization

衰老会抑制艰难梭菌重症感染期间的肠道固有免疫反应，并与细胞因子水平改变和粒细胞动员有关。

The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis

JAK抑制剂鲁索替尼可减轻ILC3非依赖性先天免疫性结肠炎模型中的炎症。