日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression

肿瘤抑制因子的缺失会促进炎症性肿瘤微环境的形成,并增强LAG3+T细胞介导的免疫抑制。

Sara Zahraeifard #,Zhiguang Xiao #,Jae Young So #,Abdul Ahad,Selina Montoya,Woo Yong Park,Trinadharao Sornapudi,Tiffany Andohkow,Abigail Read,Noemi Kedei,Vishal Koparde,Howard Yang,Maxwell Lee,Nathan Wong,Maggie Cam,Kun Wang,Eytan Ruppin,Ji Luo,Christine Hollander,Li Yang

Protein phosphatase 6 activates NF-κB to confer sensitivity to MAPK pathway inhibitors in KRAS- and BRAF-mutant cancer cells

蛋白磷酸酶 6 激活 NF-κB,使 KRAS 和 BRAF 突变癌细胞对 MAPK 通路抑制剂产生敏感性

Haibo Zhang, Abigail Read, Christophe Cataisson, Howard H Yang, Wei-Chun Lee, Benjamin E Turk, Stuart H Yuspa, Ji Luo

SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response

SF3B1 热点突变通过引发有缺陷的复制应激反应而赋予对 PARP 抑制的敏感性

Philip Bland, Harry Saville, Patty T Wai, Lucinda Curnow, Gareth Muirhead, Jadwiga Nieminuszczy, Nivedita Ravindran, Marie Beatrix John, Somaieh Hedayat, Holly E Barker, James Wright, Lu Yu, Ioanna Mavrommati, Abigail Read, Barrie Peck, Mark Allen, Patrycja Gazinska, Helen N Pemberton, Aditi Gulati,

Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation

热点 SF3B1 突变会诱导代谢重编程和对丝氨酸缺乏的脆弱性

W Brian Dalton, Eric Helmenstine, Noel Walsh, Lukasz P Gondek, Dhanashree S Kelkar, Abigail Read, Rachael Natrajan, Eric S Christenson, Barbara Roman, Samarjit Das, Liang Zhao, Robert D Leone, Daniel Shinn, Taylor Groginski, Anil K Madugundu, Arun Patil, Daniel J Zabransky, Arielle Medford, Justin L

One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation

一步永生化具有致癌转化能力的原代人气道上皮细胞

Jordan L Smith #, Liam C Lee #, Abigail Read, Qiuning Li, Bing Yu, Chih-Shia Lee, Ji Luo