SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response
SF3B1 热点突变通过引发有缺陷的复制应激反应而赋予对 PARP 抑制的敏感性
期刊:Nature Genetics
影响因子:31.7
doi:10.1038/s41588-023-01460-5
Philip Bland, Harry Saville, Patty T Wai, Lucinda Curnow, Gareth Muirhead, Jadwiga Nieminuszczy, Nivedita Ravindran, Marie Beatrix John, Somaieh Hedayat, Holly E Barker, James Wright, Lu Yu, Ioanna Mavrommati, Abigail Read, Barrie Peck, Mark Allen, Patrycja Gazinska, Helen N Pemberton, Aditi Gulati,