日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of Snhg5 disrupts cell-cycle regulation without altering cystogenesis in a mouse model of polycystic kidney disease

在多囊肾病小鼠模型中,Snhg5 的缺失会破坏细胞周期调控,但不会改变囊肿的形成。

D'Amico, Stephen; Dar, Ujala; Eckberg, Kara; Weisser, Ivan; Hossain, Chandrema; Bronstein, Robert; Aboudehen, Karam

An RNA transmethylation pathway governs kidney nephrogenic potential.

RNA转甲基化途径控制肾脏的肾形成潜能

Ramalingam Harini, Alvarez Jesus, Flaten Andrea, Cobo-Stark Patricia, Foster Nicholas, Grilli Elyse, Lakhia Ronak, Aboudehen Karam, Carroll Thomas, Patel Vishal

Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease.

长链非编码RNA Hoxb3os的缺失加剧了小鼠多囊肾病中的囊肿形成

Weisser Ivan, Eckberg Kara, D'Amico Stephen, Buttram Daniel, Aboudehen Karam

Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth

后肾器官培养中的小发夹抑制 RNA 传递鉴定出长链非编码 RNA Pvt1 是囊肿生长的调节因子

Kara Eckberg, Ivan Weisser, Daniel Buttram, Nikunj Somia, Peter Igarashi, Karam S Aboudehen

Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression

间质性微小RNA miR-214可减轻炎症和多囊肾疾病的进展

Ronak Lakhia, Matanel Yheskel, Andrea Flaten, Harini Ramalingam, Karam Aboudehen, Silvia Ferrè, Laurence Biggers, Abheepsa Mishra, Christopher Chaney, Darren P Wallace, Thomas Carroll, Peter Igarashi, Vishal Patel

Regulation of mTOR signaling by long non-coding RNA

长链非编码RNA对mTOR信号通路的调控

Aboudehen, Karam

Mechanism of Fibrosis in HNF1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease

HNF1B相关常染色体显性遗传性肾小管间质疾病的纤维化机制

Siu Chiu Chan ,Ying Zhang ,Annie Shao ,Svetlana Avdulov ,Jeremy Herrera ,Karam Aboudehen ,Marco Pontoglio ,Peter Igarashi

Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling

长链非编码 RNA Hoxb3os 在常染色体显性多囊肾病中失调并调节 mTOR 信号传导

Karam Aboudehen, Shayan Farahani, Mohammed Kanchwala, Siu Chiu Chan, Svetlana Avdulov, Alan Mickelson, Dayeon Lee, Micah D Gearhart, Vishal Patel, Chao Xing, Peter Igarashi

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism

microRNA-17家族通过调节线粒体代谢促进多囊肾病进展

Sachin Hajarnis ,Ronak Lakhia ,Matanel Yheskel ,Darren Williams ,Mehran Sorourian ,Xueqing Liu ,Karam Aboudehen ,Shanrong Zhang ,Kara Kersjes ,Ryan Galasso ,Jian Li ,Vivek Kaimal ,Steven Lockton ,Scott Davis ,Andrea Flaten ,Joshua A Johnson ,William L Holland ,Christine M Kusminski ,Philipp E Scherer ,Peter C Harris ,Marie Trudel ,Darren P Wallace ,Peter Igarashi ,Edmund C Lee ,John R Androsavich ,Vishal Patel

Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1β drives autosomal dominant tubulointerstitial kidney disease.

HNF1β 导致钾通道 Kir5.1 转录激活丧失,从而引发常染色体显性肾小管间质性肾病

Kompatscher Andreas, de Baaij Jeroen H F, Aboudehen Karam, Hoefnagels Anke P W M, Igarashi Peter, Bindels René J M, Veenstra Gertjan J C, Hoenderop Joost G J