A hotspot phosphorylation site on SHP2 drives oncoprotein activation and drug resistance
SHP2上的热点磷酸化位点驱动癌蛋白活化和耐药性。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70060-8
Karunaraj, Prashath; Scheele, Remkes; Wells, Malcolm L; Rathod, Ruchita; Gokulu, Ipek S; Abrahamson, Sophia R; Taylor, Lila; Chowdhury, Lamia; Kazmi, Abiha; Song, Weixiao; Hornbeck, Peter V; Li, Jing; Glasgow, Anum; Vasan, Neil