日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A new tractable method for generating human alveolar macrophage-like cells in vitro to study lung inflammatory processes and diseases

一种在体外生成人肺泡巨噬细胞样细胞的新型简便方法,可用于研究肺部炎症过程和疾病。

Susanta Pahari ,Eusondia Arnett ,Jan Simper ,Abul Azad ,Israel Guerrero-Arguero ,Chengjin Ye ,Hao Zhang ,Hong Cai ,Yufeng Wang ,Zhao Lai ,Natalie Jarvis ,Miranda Lumbreras ,Diego Jose Maselli ,Jay Peters ,Jordi B Torrelles ,Luis Martinez-Sobrido ,Larry S Schlesinger

A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseases

一种体外生成人类肺泡巨噬细胞样细胞用于研究肺部炎症过程和疾病的新方法

Susanta Pahari, Eusondia Arnett, Jan Simper, Abul Azad, Israel Guerrero-Arguero, Chengjin Ye, Hao Zhang, Hong Cai, Yufeng Wang, Zhao Lai, Natalie Jarvis, Miranda Lumbreras, Diego Jose Maselli-Caceres, Jay Peters, Jordi B Torrelles, Luis Martinez-Sobrido, Larry S Schlesinger

Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer

吉西他滨诱导的 TIMP1 减弱胰腺癌治疗反应并促进肿瘤生长和肝转移

Zenobia D'Costa, Keaton Jones, Abul Azad, Ruud van Stiphout, Su Y Lim, Ana L Gomes, Paul Kinchesh, Sean C Smart, W Gillies McKenna, Francesca M Buffa, Owen J Sansom, Ruth J Muschel, Eric O'Neill, Emmanouil Fokas

PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy

PD-L1 阻断可增强胰腺导管腺癌对放射治疗的反应

Abul Azad, Su Yin Lim, Zenobia D'Costa, Keaton Jones, Angela Diana, Owen J Sansom, Philipp Kruger, Stanley Liu, W Gillies McKenna, Omer Dushek, Ruth J Muschel, Emmanouil Fokas

An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse

一种高效、稳健的 MRI 引导放射治疗计划方法,用于针对小鼠腹部器官和肿瘤

Veerle Kersemans, John S Beech, Stuart Gilchrist, Paul Kinchesh, Philip D Allen, James Thompson, Ana L Gomes, Zenobia D'Costa, Luke Bird, Iain D C Tullis, Robert G Newman, Aurelien Corroyer-Dulmont, Nadia Falzone, Abul Azad, Katherine A Vallis, Owen J Sansom, Ruth J Muschel, Borivoj Vojnovic, Mark A

Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma

PD-1/PD-L1、CD8 和 FOXP3 在胰腺导管腺癌中的预后价值、定位和与促纤维化基质的相关性

Angela Diana, Lai Mun Wang, Zenobia D'Costa, Paul Allen, Abul Azad, Michael A Silva, Zahir Soonawalla, Stanley Liu, W Gillies McKenna, Ruth J Muschel, Emmanouil Fokas

Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase

β-HPV5 E6 抵抗紫外线诱导的细胞凋亡涉及通过募集 HERC1 泛素连接酶靶向活化的 BAK 进行蛋白水解

Amy Holloway, Mark Simmonds, Abul Azad, Joanna L Fox, Alan Storey

Chk1 activity is required for BAK multimerization in association with PUMA during mitochondrial apoptosis

在线粒体凋亡过程中,Chk1 活性是 BAK 多聚化与 PUMA 结合所必需的

Abul Azad, Alan Storey

BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove

BAK 疏水沟中带负电荷的残基可抑制 BAK 多聚化导致的细胞凋亡,但不抑制 bid 结合

Abul Azad, Alan Storey

Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis

通过抑制磷酸化阻断BAK疏水沟来调节细胞凋亡

Abul Azad, Joanna Fox, Sabrina Leverrier, Alan Storey