Discovery of AMG 133, a Glucose-Dependent Insulinotropic Polypeptide Receptor Antagonist and Glucagon-Like Peptide 1 Receptor Agonist Antibody-Drug Conjugate for the Treatment of Obesity
发现 AMG 133，一种葡萄糖依赖性胰岛素促泌多肽受体拮抗剂和胰高血糖素样肽-1受体激动剂抗体-药物偶联物，用于治疗肥胖症
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.6c00032
Wu, Bin; Falsey, James R; Netirojjanakul, Chawita; Herberich, Brad; Holder, Jerry Ryan; Sham, Kelvin; Aral, Jennifer; Forsythe, Neil; Walker, Kenneth W; Lu, Shu-Chen; Hager, Todd; Stanislaus, Shanaka; Komorowski, Renee; Atangan, Larissa; Achmatowicz, Michal; Romanini, Dante; Weeraratne, Dohan; Miranda, Les P; Véniant, Murielle M; Cheng, Yuan
