日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Recent progress in mass spectrometry-based strategies for elucidating protein-protein interactions

近年来,基于质谱的蛋白质-蛋白质相互作用研究策略取得了显著进展。

Low, Teck Yew; Syafruddin, Saiful Effendi; Mohtar, M Aiman; Vellaichamy, Adaikkalam; A Rahman, Nisa Syakila; Pung, Yuh-Fen; Tan, Chris Soon Heng

Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics

蛋白质组学揭示火疫病欧文氏菌菌株的赖氨酸乙酰化差异

Xia Wu, Adaikkalam Vellaichamy, Dongping Wang, Leonid Zamdborg, Neil L Kelleher, Steven C Huber, Youfu Zhao

Mapping intact protein isoforms in discovery mode using top-down proteomics

利用自上而下的蛋白质组学方法,以发现模式绘制完整蛋白质亚型图谱

Tran, John C; Zamdborg, Leonid; Ahlf, Dorothy R; Lee, Ji Eun; Catherman, Adam D; Durbin, Kenneth R; Tipton, Jeremiah D; Vellaichamy, Adaikkalam; Kellie, John F; Li, Mingxi; Wu, Cong; Sweet, Steve M M; Early, Bryan P; Siuti, Nertila; LeDuc, Richard D; Compton, Philip D; Thomas, Paul M; Kelleher, Neil L

An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

前列腺癌进展中雄激素受体、多梳和 TMPRSS2-ERG 基因融合的综合网络

Jindan Yu, Jianjun Yu, Ram-Shankar Mani, Qi Cao, Chad J Brenner, Xuhong Cao, Xiaoju Wang, Longtao Wu, James Li, Ming Hu, Yusong Gong, Hong Cheng, Bharathi Laxman, Adaikkalam Vellaichamy, Sunita Shankar, Yong Li, Saravana M Dhanasekaran, Roger Morey, Terrence Barrette, Robert J Lonigro, Scott A Tomli

Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa

尺寸分选与改进的纳米毛细管液相色谱-质谱法相结合,用于鉴定高达 80 kDa 的完整蛋白质

Adaikkalam Vellaichamy, John C Tran, Adam D Catherman, Ji Eun Lee, John F Kellie, Steve M M Sweet, Leonid Zamdborg, Paul M Thomas, Dorothy R Ahlf, Kenneth R Durbin, Gary A Valaskovic, Neil L Kelleher

The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput

自上而下质谱法在蛋白质分析中的应用:生物标志物、蛋白质治疗及高通量分析

Kellie, John F; Tran, John C; Lee, Ji Eun; Ahlf, Dorothy R; Thomas, Haylee M; Ntai, Ioanna; Catherman, Adam D; Durbin, Kenneth R; Zamdborg, Leonid; Vellaichamy, Adaikkalam; Thomas, Paul M; Kelleher, Neil L

A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome

一种用于低质量蛋白质组自上而下串联质谱分析的稳健二维分离方法

Lee, Ji Eun; Kellie, John F; Tran, John C; Tipton, Jeremiah D; Catherman, Adam D; Thomas, Haylee M; Ahlf, Dorothy R; Durbin, Kenneth R; Vellaichamy, Adaikkalam; Ntai, Ioanna; Marshall, Alan G; Kelleher, Neil L

Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases

通过蛋白质组学研究雄激素在前列腺癌细胞中的作用,揭示了氨酰tRNA合成酶的作用

Vellaichamy, Adaikkalam; Sreekumar, Arun; Strahler, John R; Rajendiran, Theckelnaycke; Yu, Jindan; Varambally, Sooryanarayana; Li, Yong; Omenn, Gilbert S; Chinnaiyan, Arul M; Nesvizhskii, Alexey I

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer

高尔基体蛋白GOLM1是前列腺癌的组织和尿液生物标志物。

Varambally, Sooryanarayana; Laxman, Bharathi; Mehra, Rohit; Cao, Qi; Dhanasekaran, Saravana M; Tomlins, Scott A; Granger, Jill; Vellaichamy, Adaikkalam; Sreekumar, Arun; Yu, Jianjun; Gu, Wenjuan; Shen, Ronglai; Ghosh, Debashis; Wright, Lorinda M; Kladney, Raleigh D; Kuefer, Rainer; Rubin, Mark A; Fimmel, Claus J; Chinnaiyan, Arul M

Loss of Raf kinase inhibitory protein induces radioresistance in prostate cancer

Raf激酶抑制蛋白的缺失会导致前列腺癌产生放射抗性

Woods Ignatoski, Kathleen M; Grewal, Navdeep K; Markwart, Sonja M; Vellaichamy, Adaikkalam; Chinnaiyan, Arul M; Yeung, Kam; Ray, Michael E; Keller, Evan T