Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity
针对 I 型胰岛素样生长因子受体的稳定 IgG 样双特异性抗体表现出增强的配体阻断和抗肿瘤活性
期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.M110.184317
Jianying Dong, Arlene Sereno, William B Snyder, Brian R Miller, Susan Tamraz, Adam Doern, Michael Favis, Xiufeng Wu, Hon Tran, Emma Langley, Ingrid Joseph, Antonio Boccia, Rebecca Kelly, Kathleen Wortham, Qin Wang, Lisa Berquist, Flora Huang, Sharon X Gao, Ying Zhang, Alexey Lugovskoy, Shelly Martin