日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity

针对 I 型胰岛素样生长因子受体的稳定 IgG 样双特异性抗体表现出增强的配体阻断和抗肿瘤活性

Jianying Dong, Arlene Sereno, William B Snyder, Brian R Miller, Susan Tamraz, Adam Doern, Michael Favis, Xiufeng Wu, Hon Tran, Emma Langley, Ingrid Joseph, Antonio Boccia, Rebecca Kelly, Kathleen Wortham, Qin Wang, Lisa Berquist, Flora Huang, Sharon X Gao, Ying Zhang, Alexey Lugovskoy, Shelly Martin

Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTbetaR

针对 TRAIL-R2 和 LTbetaR 的稳定性工程 IgG 样双特异性抗体的抗肿瘤活性

Jennifer S Michaelson, Stephen J Demarest, Brian Miller, Aldo Amatucci, William B Snyder, Xiufeng Wu, Flora Huang, Samantha Phan, Sharon Gao, Adam Doern, Graham K Farrington, Alexey Lugovskoy, Ingrid Joseph, Veronique Bailly, Xin Wang, Ellen Garber, Jeff Browning, Scott M Glaser

Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo

具有不同表位特异性和配体阻断特性的抑制性抗胰岛素样生长因子受体抗体的表征:对体内作用机制的影响

Adam Doern, Xianjun Cao, Arlene Sereno, Christopher L Reyes, Angelina Altshuler, Flora Huang, Cathy Hession, Albert Flavier, Michael Favis, Hon Tran, Eric Ailor, Melissa Levesque, Tracey Murphy, Lisa Berquist, Susan Tamraz, Tracey Snipas, Ellen Garber, William S Shestowsky, Rachel Rennard, Christily