日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dim Flicker: An Endogenous Visual Percept and Its Disease Associations

微弱闪烁:一种内源性视觉感知及其与疾病的关联

Amini, Abdullah; Besic, Adam; Freund, Avery; Subhi, Yousif; Klefter, Oliver Niels; Olesen, Jes; Frederiksen, Jette Lautrup; Larsen, Michael

Dietary restriction impacts health and lifespan of genetically diverse mice

饮食限制会影响遗传多样性小鼠的健康和寿命。

Andrea Di Francesco ,Andrew G Deighan ,Lev Litichevskiy ,Zhenghao Chen ,Alison Luciano ,Laura Robinson ,Gaven Garland ,Hannah Donato ,Matthew Vincent ,Will Schott ,Kevin M Wright ,Anil Raj ,G V Prateek ,Martin Mullis ,Warren G Hill ,Mark L Zeidel ,Luanne L Peters ,Fiona Harding ,David Botstein ,Ron Korstanje ,Christoph A Thaiss ,Adam Freund ,Gary A Churchill

An immune-based tool platform for in vivo cell clearance

基于免疫的体内细胞清除工具平台

Jieqiong Zhang, Tatsuya Tsukui, Xiumin Wu, Alyssa Brito, John Maxwell Trumble, Juan C Caraballo, Greg M Allen, José Zavala-Solorio, Chunlian Zhang, Jonathan Paw, Wendell A Lim, Jiefei Geng, Yuliya Kutskova, Adam Freund, Ganesh Kolumam, Dean Sheppard, Robert L Cohen

Novel insights from a multiomics dissection of the Hayflick limit

通过多组学方法剖析海弗里克极限,我们获得了新的见解

Michelle Chan ,Han Yuan # ,Ilya Soifer # ,Tobias M Maile ,Rebecca Y Wang ,Andrea Ireland ,Jonathon J O'Brien ,Jérôme Goudeau ,Leanne J G Chan ,Twaritha Vijay ,Adam Freund ,Cynthia Kenyon ,Bryson D Bennett ,Fiona E McAllister ,David R Kelley ,Margaret Roy ,Robert L Cohen ,Arthur D Levinson ,David Botstein ,David G Hendrickson

Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells

抑制长寿调节因子PAPP-A可通过抑制间充质基质细胞来调节组织稳态。

Mary Mohrin ,Justin Liu ,Jose Zavala-Solorio ,Sakshi Bhargava ,John Maxwell Trumble ,Alyssa Brito ,Dorothy Hu ,Daniel Brooks ,Georgios Koukos ,Lama Alabdulaaly ,Jonathan S Paw ,Kayley Hake ,Ganesh Kolumam ,Mary L Bouxsein ,Roland Baron ,Yuliya Kutskova ,Adam Freund

An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1

基于 RNA 构象并由 TCAB1 塑造的人类端粒酶活性开关

Lu Chen, Caitlin M Roake, Adam Freund, Pedro J Batista, Siqi Tian, Yi A Yin, Chandresh R Gajera, Shengda Lin, Byron Lee, Matthew F Pech, Andrew S Venteicher, Rhiju Das, Howard Y Chang, Steven E Artandi

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells

双重 SMAD 信号抑制可实现多种上皮基底细胞的长期扩增

Hongmei Mou, Vladimir Vinarsky, Purushothama Rao Tata, Karissa Brazauskas, Soon H Choi, Adrianne K Crooke, Bing Zhang, George M Solomon, Brett Turner, Hermann Bihler, Jan Harrington, Allen Lapey, Colleen Channick, Colleen Keyes, Adam Freund, Steven Artandi, Martin Mense, Steven Rowe, John F Engelhar

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

MTOR 通过促进 IL1A 翻译来调节促肿瘤发生的衰老相关分泌表型

Remi-Martin Laberge, Yu Sun, Arturo V Orjalo, Christopher K Patil, Adam Freund, Lili Zhou, Samuel C Curran, Albert R Davalos, Kathleen A Wilson-Edell, Su Liu, Chandani Limbad, Marco Demaria, Patrick Li, Gene B Hubbard, Yuji Ikeno, Martin Javors, Pierre-Yves Desprez, Christopher C Benz, Pankaj Kapahi

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1

通过 TRiC 介导的 TCAB1 折叠进行蛋白稳态控制端粒酶功能

Adam Freund, Franklin L Zhong, Andrew S Venteicher, Zhaojing Meng, Timothy D Veenstra, Judith Frydman, Steven E Artandi

Glucocorticoids suppress selected components of the senescence-associated secretory phenotype

糖皮质激素抑制衰老相关分泌表型的某些成分

Remi-Martin Laberge, Lili Zhou, Melissa R Sarantos, Francis Rodier, Adam Freund, Peter L J de Keizer, Su Liu, Marco Demaria, Yu-Sheng Cong, Pankaj Kapahi, Pierre-Yves Desprez, Robert E Hughes, Judith Campisi