Blocking of interferon regulatory factor 1 reduces tumor necrosis factor α-induced interleukin-18 bioactivity in rheumatoid arthritis synovial fibroblasts by induction of interleukin-18 binding protein a: role of the nuclear interferon regulatory factor 1-NF-κB-c-jun complex

阻断干扰素调节因子 1 可降低肿瘤坏死因子 α 诱导的类风湿关节炎滑膜成纤维细胞中的白细胞介素 18 生物活性，这是通过诱导白细胞介素 18 结合蛋白 a 实现的：核干扰素调节因子 1-NF-κB-c-jun 复合物的作用