Adam Leach相关文献与解析，生知库 | 链接生命科学的每一步

Quantification and prognostic significance of interferon-γ secreting SARS-CoV-2 responsive T cells in hospitalized patients with acute COVID-19

急性COVID-19住院患者中分泌干扰素-γ的SARS-CoV-2反应性T细胞的定量及其预后意义

doi:10.1016/j.jinf.2021.11.010

Pan, Daniel; Kim, Jee Whang; Nazareth, Joshua; Assadi, Sara; Bellass, Adam; Leach, Jack; Brosnan, James G; Ahmed, Adam; Starcevic, Fleur; Sze, Shirley; Martin, Christopher A; Williams, Caroline M; Barer, Michael R; Sahota, Amandip; Patel, Prashanth; Tattersall, Andrea; Cooper, Andrea; Pareek, Manish; Haldar, Pranabashis

Enhanced target-specific delivery of docetaxel-loaded nanoparticles using engineered T cell receptors

利用工程化T细胞受体增强多西他赛纳米颗粒的靶向递送

期刊:Nanoscale

影响因子:5.8

doi:10.1039/d1nr04001d

William J McDaid ，Nikolai Lissin ，Ellen Pollheimer ，Michelle Greene ，Adam Leach ，Peter Smyth ，Giovanna Bossi ，Daniel Longley ，David K Cole ，Christopher J Scott

A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency

四聚体 ACE2 蛋白可广泛中和令人担忧的 SARS-CoV-2 刺突蛋白变体，且效力增强

期刊:Antiviral Research

影响因子:4.5

doi:10.1016/j.antiviral.2021.105147

Adam Leach, F Tudor Ilca, Zulaikha Akbar, Mathieu Ferrari, Emma M Bentley, Giada Mattiuzzo, Shimobi Onuoha, Ami Miller, Hanif Ali, Terence H Rabbitts

A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection

超强四聚化 ACE2 蛋白表现出增强的 SARS-CoV-2 病毒感染中和作用

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-89957-z

Ami Miller, Adam Leach, Jemima Thomas, Craig McAndrew, Emma Bentley, Giada Mattiuzzo, Lijo John, Ali Mirazimi, Gemma Harris, Nadisha Gamage, Stephen Carr, Hanif Ali, Rob Van Montfort, Terence Rabbitts

Implementing a method for engineering multivalency to substantially enhance binding of clinical trial anti-SARS-CoV-2 antibodies to wildtype spike and variants of concern proteins

实施一种设计多价性的方法，以显著增强临床试验抗 SARS-CoV-2 抗体与野生型刺突蛋白和关注变体蛋白的结合

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-89887-w

Adam Leach #, Ami Miller #, Emma Bentley, Giada Mattiuzzo, Jemima Thomas, Craig McAndrew, Rob Van Montfort, Terence Rabbitts

Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature

抗 DLL4 VNAR 靶向纳米粒子，用于靶向肿瘤和肿瘤相关血管

期刊:Nanoscale

影响因子:5.8

doi:10.1039/d0nr02962a

Adam Leach, Peter Smyth, Laura Ferguson, John Steven, Michelle K Greene, Cristina M Branco, Aidan P McCann, Andrew Porter, Caroline J Barelle, Christopher J Scott

肿瘤

发表日期：2020

文献求助收藏

Perspectives of Yukon's frontline health care workers during the COVID-19 pandemic

育空地区一线医护人员在新冠疫情期间的视角

Quantification and prognostic significance of interferon-γ secreting SARS-CoV-2 responsive T cells in hospitalized patients with acute COVID-19

急性COVID-19住院患者中分泌干扰素-γ的SARS-CoV-2反应性T细胞的定量及其预后意义

Enhanced target-specific delivery of docetaxel-loaded nanoparticles using engineered T cell receptors

利用工程化T细胞受体增强多西他赛纳米颗粒的靶向递送

A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency

四聚体 ACE2 蛋白可广泛中和令人担忧的 SARS-CoV-2 刺突蛋白变体，且效力增强

A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection

超强四聚化 ACE2 蛋白表现出增强的 SARS-CoV-2 病毒感染中和作用

Implementing a method for engineering multivalency to substantially enhance binding of clinical trial anti-SARS-CoV-2 antibodies to wildtype spike and variants of concern proteins

实施一种设计多价性的方法，以显著增强临床试验抗 SARS-CoV-2 抗体与野生型刺突蛋白和关注变体蛋白的结合

Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature

抗 DLL4 VNAR 靶向纳米粒子，用于靶向肿瘤和肿瘤相关血管