日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

One N-glycan regulates natural killer cell antibody-dependent cell-mediated cytotoxicity and modulates Fc γ receptor IIIa/CD16a structure

一种 N-糖调节自然杀伤细胞抗体依赖性细胞介导的细胞毒性并调节 Fcγ 受体 IIIa/CD16a 结构

Paul G Kremer, Elizabeth A Lampros, Allison M Blocker, Adam W Barb

Distinct CD16a features on human NK cells observed by flow cytometry correlate with increased ADCC

流式细胞术观察到的人类NK细胞上独特的CD16a特征与ADCC增强相关。

Maria C Rodriguez Benavente ,Zainab A Hakeem ,Alexander R Davis ,Nathan B Murray ,Parastoo Azadi ,Emily M Mace ,Adam W Barb

One N-glycan regulates natural killer cell antibody-dependent cell-mediated cytotoxicity and modulates Fc γ receptor IIIa / CD16a structure

一种 N-糖调节自然杀伤细胞抗体依赖性细胞介导的细胞毒性并调节 Fcγ 受体 IIIa/CD16a 结构

Paul G Kremer, Elizabeth A Lampros, Allison M Blocker, Adam W Barb

Inhibiting N-glycan processing increases the antibody binding affinity and effector function of human natural killer cells

抑制N-糖基化加工可提高抗体结合亲和力和人自然杀伤细胞的效应功能。

Maria Carolina Rodriguez Benavente ,Harrison B Hughes ,Paul G Kremer ,Ganesh P Subedi ,Adam W Barb

Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques

解读人与恒河猴 Fc 效应功能之间的种间差异:恒河猴 CD16 依赖性效应功能的结构基础

William D Tolbert, Neelakshi Gohain, Paul G Kremer, Andrew P Hederman, Dung N Nguyen, Verna Van, Rebekah Sherburn, George K Lewis, Andrés Finzi, Justin Pollara, Margaret E Ackerman, Adam W Barb, Marzena Pazgier

The weaker-binding Fc γ receptor IIIa F158 allotype retains sensitivity to N-glycan composition and exhibits a destabilized antibody-binding interface

结合力较弱的 Fcγ受体IIIa F158同种型保留了对N-糖组成的敏感性,并表现出不稳定的抗体结合界面

Paul G Kremer, Adam W Barb

Method for Identifying Galectin Ligands on Lymphocyte Membrane Glycoproteins

淋巴细胞膜糖蛋白上半乳糖凝集素配体的鉴定方法

Kashyap R Patel, Adam W Barb, Sean R Stowell

The antibody-binding Fc gamma receptor IIIa / CD16a is N-glycosylated with high occupancy at all five sites

抗体结合的 Fc γ 受体 IIIa/CD16a 在所有五个位点均被 N-糖基化,且占有率较高

Elizabeth A Lampros, Paul G Kremer, Jesús S Aguilar Díaz de León, Elijah T Roberts, Maria Carolina Rodriguez Benavente, I Jonathan Amster, Adam W Barb

Fc γ receptor IIIa/CD16a processing correlates with the expression of glycan-related genes in human natural killer cells

Fcγ受体IIIa/CD16a加工与人类自然杀伤细胞中聚糖相关基因表达相关

Kashyap R Patel, Maria C Rodriguez Benavente, W Walter Lorenz, Emily M Mace, Adam W Barb

Expression and Display of Glycoengineered Antibodies and Antibody Fragments with an Engineered Yeast Strain

利用工程酵母菌株表达和展示糖工程抗体和抗体片段

Anjali Shenoy, Srisaimaneesh Yalamanchili, Alexander R Davis, Adam W Barb