日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

De Novo Design of High-Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor

从头设计靶向土拉弗朗西斯菌毒力因子的高亲和力微型蛋白结合剂

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202516058
Gokce-Alpkilic, Gizem; Huang, Buwei; Liu, Andi; Kreuk, Lieselotte S M; Wang, Yaxi; Adebomi, Victor; Bueso, Yensi Flores; Bera, Asim K; Kang, Alex; Gerben, Stacey R; Rettie, Stephen; Vafeados, Dionne K; Roullier, Nicole; Goreshnik, Inna; Li, Xinting; Baker, David; Woodward, Joshua J; Mougous, Joseph D; Bhardwaj, Gaurav
微生物学
发表日期：2025
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Accurate de novo design of high-affinity protein-binding macrocycles using deep learning

利用深度学习进行高亲和力蛋白质结合大环化合物的精确从头设计

期刊:Nature Chemical Biology
影响因子:13.7
doi:10.1038/s41589-025-01929-w
Rettie, Stephen A; Juergens, David; Adebomi, Victor; Bueso, Yensi Flores; Zhao, Qinqin; Leveille, Alexandria N; Liu, Andi; Bera, Asim K; Wilms, Joana A; Üffing, Alina; Kang, Alex; Brackenbrough, Evans; Lamb, Mila; Gerben, Stacey R; Murray, Analisa; Levine, Paul M; Schneider, Maika; Vasireddy, Vibha; Ovchinnikov, Sergey; Weiergräber, Oliver H; Willbold, Dieter; Kritzer, Joshua A; Mougous, Joseph D; Baker, David; DiMaio, Frank; Bhardwaj, Gaurav
发表日期：2025
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De novo design of high-affinity miniprotein binders targeting Francisella tularensis virulence factor.

从头设计针对土拉弗朗西斯菌毒力因子的高亲和力小蛋白结合剂

期刊:
影响因子:
doi:10.1101/2025.07.02.662053
Gokce-Alpkilic Gizem, Huang Buwei, Liu Andi, Kreuk Lieselotte S M, Wang Yaxi, Adebomi Victor, Bueso Yensi Flores, Bera Asim K, Kang Alex, Gerben Stacey R, Rettie Stephen, Vafeados Dionne K, Roullier Nicole, Goreshnik Inna, Li Xinting, Baker David, Woodward Joshua J, Mougous Joseph D, Bhardwaj Gaurav
其它
肠道菌群
发表日期：2025
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A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries

用于合成和筛选环肽库的无标签平台

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202320045
Bruce, Angele; Adebomi, Victor; Czabala, Patrick; Palmer, Jonathan; McFadden, William M; Lorson, Zachary C; Slack, Ryan L; Bhardwaj, Gaurav; Sarafianos, Stefan G; Raj, Monika
发表日期：2024
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Accurate de novo design of high-affinity protein binding macrocycles using deep learning

利用深度学习进行高亲和力蛋白质结合大环化合物的精确从头设计

期刊:
影响因子:
doi:10.1101/2024.11.18.622547
Rettie, Stephen A; Juergens, David; Adebomi, Victor; Bueso, Yensi Flores; Zhao, Qinqin; Leveille, Alexandria N; Liu, Andi; Bera, Asim K; Wilms, Joana A; Üffing, Alina; Kang, Alex; Brackenbrough, Evans; Lamb, Mila; Gerben, Stacey R; Murray, Analisa; Levine, Paul M; Schneider, Maika; Vasireddy, Vibha; Ovchinnikov, Sergey; Weiergräber, Oliver H; Willbold, Dieter; Kritzer, Joshua A; Mougous, Joseph D; Baker, David; DiMaio, Frank; Bhardwaj, Gaurav
发表日期：2024
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Intramolecular Hydrogen Bonding Enables a Zwitterionic Mechanism for Macrocyclic Peptide Formation: Computational Mechanistic Studies of CyClick Chemistry

分子内氢键促进大环肽形成的两性离子机制：CyClick化学的计算机理研究

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202307210
Shao, Huiling; Adebomi, Victor; Bruce, Angele; Raj, Monika; Houk, Kendall N
发表日期：2023
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Cyclic peptide structure prediction and design using AlphaFold

利用AlphaFold进行环肽结构预测和设计

期刊:
影响因子:
doi:10.1101/2023.02.25.529956
Rettie, Stephen A; Campbell, Katelyn V; Bera, Asim K; Kang, Alex; Kozlov, Simon; De La Cruz, Joshmyn; Adebomi, Victor; Zhou, Guangfeng; DiMaio, Frank; Ovchinnikov, Sergey; Bhardwaj, Gaurav
发表日期：2023
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Selective Conversion of Unactivated C-N Amide Bond to C-C bond via Steric and Electronic Resonance Destabilization

通过空间和电子共振去稳定化将未活化的CN酰胺键选择性地转化为CC键

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.2c02420
Adebomi, Victor; Wang, Yuwen; Sriram, Mahesh; Raj, Monika
发表日期：2022
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Synthesis of L-cyclic tetrapeptides by backbone amide activation CyClick strategy

利用骨架酰胺活化CyClick策略合成L-环状四肽

期刊:Tetrahedron
影响因子:2.2
doi:10.1016/j.tet.2022.133071
Wills, Rachel; Adebomi, Victor; Spancake, Caroline; Cohen, Ryan D; Raj, Monika
发表日期：2022
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