日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER- breast cancer

肿瘤NOS2/COX2水平升高会促进与ER阴性乳腺癌患者预后不良相关的免疫抑制表型。

Ridnour, Lisa A; Cheng, Robert Ys; Heinz, William F; Pore, Milind; Gonzalez, Ana L; Femino, Elise L; Moffat, Rebecca L; Wink, Adelaide L; Imtiaz, Fatima; Coutinho, Leandro L; Butcher, Donna; Edmondson, Elijah F; Rangel, M Cristina; Wong, Stephen Tc; Lipkowitz, Stanley; Glynn, Sharon A; Vitek, Michael P; McVicar, Daniel W; Li, Xiaoxian; Anderson, Stephen K; Paolocci, Nazareno; Hewitt, Stephen M; Ambs, Stefan; Billiar, Timothy R; Chang, Jenny C; Lockett, Stephen J; Wink, David A

Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors

辅助性COX抑制剂可增强STING信号传导和细胞毒性T细胞在受照射的4T1肿瘤中的浸润

Lisa A Ridnour ,Robert Ys Cheng ,Noemi Kedei ,Veena Somasundaram ,Dibyangana D Bhattacharyya ,Debashree Basudhar ,Adelaide L Wink ,Abigail J Walke ,Caleb Kim ,William F Heinz ,Elijah F Edmondson ,Donna O Butcher ,Andrew C Warner ,Tiffany H Dorsey ,Milind Pore ,Robert J Kinders ,Stanley Lipkowitz ,Richard J Bryant ,Jens Rittscher ,Stephen Tc Wong ,Stephen M Hewitt ,Jenny C Chang ,Aliaa Shalaby ,Grace M Callagy ,Sharon A Glynn ,Stefan Ambs ,Stephen K Anderson ,Daniel W McVicar ,Stephen J Lockett ,David A Wink

Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER- Breast Cancer

肿瘤 NOS2 和 COX2 与 CD8+ T 细胞的空间并置促进转移性和癌症干细胞微环境,导致 ER- 乳腺癌预后不良

Lisa A Ridnour #, William F Heinz #, Robert Y S Cheng #, Adelaide L Wink #, Noemi Kedei, Milind Pore, Fatima Imtiaz, Elise L Femino, Ana L Gonzalez, Leandro L Coutinho, Rebecca L Moffat, Donna Butcher, Elijah F Edmondson, Xiaoxian Li, Maria Cristina Rangel, Robert J Kinders, Jens Rittscher, Stanley

Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome

干扰素-γ 是内质网型乳腺肿瘤中 NOS2 和 COX2 表达的典型特征,会导致不良预后

Robert Y S Cheng #, Lisa A Ridnour #, Adelaide L Wink, Ana L Gonzalez, Elise L Femino, Helene Rittscher, Veena Somasundaram, William F Heinz, Leandro Coutinho, M Cristina Rangel, Elijah F Edmondson, Donna Butcher, Robert J Kinders, Xiaoxian Li, Stephen T C Wong, Daniel W McVicar, Stephen K Anderson,

Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients

NOS2 和 COX2 与 T 效应细胞相互作用的空间分析揭示了 ER-乳腺癌患者预后不良相关的免疫抑制景观

Lisa A Ridnour, Robert Y S Cheng, William F Heinz, Milind Pore, Ana L Gonzalez, Elise L Femino, Rebecca Moffat, Adelaide L Wink, Fatima Imtiaz, Leandro Coutinho, Donna Butcher, Elijah F Edmondson, M Cristina Rangel, Stephen T C Wong, Stanley Lipkowitz, Sharon Glynn, Michael P Vitek, Daniel W McVicar

NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer

NOS2 和 COX2 提供决定 ER-乳腺癌结果的关键空间靶点

Lisa A Ridnour, William F Heinz, Robert Ys Cheng, Adelaide L Wink, Noemi Kedei, Milind Pore, Fatima Imtiaz, Elise L Femino, Ana L Gonzalez, Leandro Coutinho, Donna Butcher, Elijah F Edmondson, M Cristina Rangel, Robert J Kinders, Stanley Lipkowitz, Stephen Tc Wong, Stephen K Anderson, Danial W McVic

Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density

系统性NOS2耗竭和COX抑制可限制三阴性乳腺癌的疾病进展,并改变淋巴细胞的空间排列和密度。

Veena Somasundaram ,Lisa A Ridnour ,Robert Ys Cheng ,Abigail J Walke ,Noemi Kedei ,Dibyangana D Bhattacharyya ,Adelaide L Wink ,Elijah F Edmondson ,Donna Butcher ,Andrew C Warner ,Tiffany H Dorsey ,David A Scheiblin ,William Heinz ,Richard J Bryant ,Robert J Kinders ,Stanley Lipkowitz ,Stephen Tc Wong ,Milind Pore ,Stephen M Hewitt ,Daniel W McVicar ,Stephen K Anderson ,Jenny Chang ,Sharon A Glynn ,Stefan Ambs ,Stephen J Lockett ,David A Wink

Child Protective Services Reports in the Context of Intimate Partner Violence: A Delphi Process Examining Best Practices

儿童保护服务报告在亲密伴侣暴力背景下的应用:一项探讨最佳实践的德尔菲法研究

Ragavan, Maya I; Skinner, Camille M; Killough, Emily F; Henderson, Cynterria; Eichman, Adelaide L; Randell, Kimberly A

"It Can Be Hard But It's Not Bad": Three Questions to Solicit Caregiver Perceptions of Benefits and Burdens to Participating in Pediatric Palliative Care Research

“这可能很艰难,但并非糟糕”:三个问题旨在了解照护者对参与儿科姑息治疗研究的益处和负担的看法

Reggio, Cheryl; Mowbray, Catriona; Waldron, Mia K; Rood, Adelaide L; Sibilia, Gabriella; Mooney-Doyle, Kim; Hinds, Pamela S

Posaconazole-induced hypertension in children with cystic fibrosis

泊沙康唑诱发囊性纤维化患儿高血压

Marpole, Rachael; Yeoh, Daniel K; Withers, Adelaide L