日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Single Dose Study of Pembrolizumab in People With HIV Infection Who are Immunologic Nonresponders

帕博利珠单抗单剂量治疗HIV感染且免疫无应答者的研究

Kuruppu, Janaki; Purdy, Julia B; Pauls, Cheryl; Rogan, Daniel C; Blazkova, Jana; Kardava, Lela; Sewack, Adeline B; Proschan, Michael A; Migueles, Stephen A; Connors, Mark; Webber, Jonathan D; Meeks, Tyler; Przygonska, Paulina A; Adelsberger, Joseph W; Higgins, Jeanette; Rupert, Adam; Moir, Susan L; Chun, Tae-Wook; Lane, H Clifford; Kovacs, Joseph A

Interleukin-27-polarized HIV-resistant M2 macrophages are a novel subtype of macrophages that express distinct antiviral gene profiles in individual cells: implication for the antiviral effect via different mechanisms in the individual cell-dependent manner.

白细胞介素-27 极化的 HIV 抗性 M2 巨噬细胞是一种新型的巨噬细胞亚型,其在单个细胞中表达不同的抗病毒基因谱:这表明其抗病毒作用是通过不同的机制以单个细胞依赖的方式实现的

Imamichi Tomozumi, Yang Jun, Chen Qian, Goswami Suranjana, Marquez Mayra, Kariyawasam Udeshika, Sharma Homa Nath, Wiscovitch-Russo Rosana, Li Xuan, Aioi Akihiro, Adelsberger Joseph W, Chang Weizhong, Higgins Jeanette, Sui Hongyan

A novel microRNA, hsa-miR-6852 differentially regulated by Interleukin-27 induces necrosis in cervical cancer cells by downregulating the FoxM1 expression

一种新型microRNA,hsa-miR-6852,受白细胞介素-27差异性调控,通过下调FoxM1表达诱导宫颈癌细胞坏死。

Poudyal, Deepak; Herman, Andrew; Adelsberger, Joseph W; Yang, Jun; Hu, Xiaojun; Chen, Qian; Bosche, Marjorie; Sherman, Brad T; Imamichi, Tomozumi

Interleukin-2 inhibits HIV-1 replication in some human T cell lymphotrophic virus-1-infected cell lines via the induction and incorporation of APOBEC3G into the virion

白细胞介素-2通过诱导APOBEC3G并将其整合到病毒颗粒中,抑制某些人类T细胞淋巴瘤病毒-1感染细胞系中的HIV-1复制。

Oguariri, Raphael M; Dai, Lue; Adelsberger, Joseph W; Rupert, Adam; Stevens, Randy; Yang, Jun; Huang, Dawei; Lempicki, Richard A; Zhou, Ming; Baseler, Michael W; Lane, H Clifford; Imamichi, Tomozumi

Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication

评估抗疟疾药物乙胺嘧啶对 HIV-1 复制的影响

Oguariri, Raphael M; Adelsberger, Joseph W; Baseler, Michael W; Imamichi, Tomozumi

Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27

非感染性乳头瘤病毒样颗粒抑制HIV-1复制:IL-27对HIV-1感染免疫控制的意义

Fakruddin, J Mohamad; Lempicki, Richard A; Gorelick, Robert J; Yang, Jun; Adelsberger, Joseph W; Garcia-Pineres, Alfonso J; Pinto, Ligia A; Lane, H Clifford; Imamichi, Tomozumi

Actinomycin D induces high-level resistance to thymidine analogs in replication of human immunodeficiency virus type 1 by interfering with host cell thymidine kinase expression

放线菌素D通过干扰宿主细胞胸苷激酶的表达,诱导人类免疫缺陷病毒1型复制过程中对胸苷类似物产生高水平的耐药性。

Imamichi, Tomozumi; Murphy, Michael A; Adelsberger, Joseph W; Yang, Jun; Watkins, Catherine M; Berg, Steve C; Baseler, Michael W; Lempicki, Richard A; Guo, Jianhui; Levin, Judith G; Lane, H Clifford