PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder.
PKC412 抑制锌指 198-成纤维细胞生长因子受体 1 融合酪氨酸激酶,可用于治疗干细胞骨髓增生性疾病
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0404438101
Chen Jing, Deangelo Daniel J, Kutok Jeffery L, Williams Ifor R, Lee Benjamin H, Wadleigh Martha, Duclos Nicole, Cohen Sarah, Adelsperger Jennifer, Okabe Rachel, Coburn Allison, Galinsky Ilene, Huntly Brian, Cohen Pamela S, Meyer Thomas, Fabbro Doriano, Roesel Johannes, Banerji Lolita, Griffin James D, Xiao Sheng, Fletcher Jonathan A, Stone Richard M, Gilliland D Gary