日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ART-free HIV-1 remission in children with in-utero HIV-1 after very early ART (IMPAACT P1115): a multicentre, open-label, phase 1/2 proof-of-concept study

早期接受抗逆转录病毒疗法(ART)后,宫内感染HIV-1的儿童可实现无ART治疗的HIV-1缓解(IMPAACT P1115):一项多中心、开放标签、1/2期概念验证研究

Persaud, Deborah; Coletti, Anne; Nelson, Bryan S; Jao, Jennifer; Capparelli, Edmund V; Costello, Diane; Tierney, Camlin; Kekitiinwa, Adeodata R; Nematadzira, Teacler; Njau, Boniface N; Moye, John; Jean-Philippe, Patrick; Korutaro, Violet; Nalugo, Annet; Mbengeranwa, Tapiwa; Chidemo, Tinashe; Mmbaga, Blandina T; Sakasaka, Philoteus A; Cotton, Mark; Jennings, Cheryl; Hoffmann, Carly; Hovind, Laura; Bryson, Yvonne; Chadwick, Ellen G

Advancing the course of HIV genomics research in Africa

推进非洲艾滋病基因组学研究进程

Agamah, Francis E; Arbuthnot, Patrick; Tindana, Paulina; Munung, Nchangwi Synthia; Kasule, Mary; Ghansah, Anita; Mosepele, Mosepele; Gaolathe, Tendani; Kekitiinwa, Adeodata; Nduati, Eunice; Jumare, Jibreel; Gómez-Olivé, Francesc Xavier; Liebenberg, Lenine; Dandara, Collet; Osawe, Sophia; Julius, Rolanda; Muzambi, Tino; Natus, Tanian; Omumbo, Judith; Mayne, Elizabeth; Abimiku, Alash'le; Richardson, Simone; Matshaba, Mogomotsi; Skelton, Michelle

Beyond the fever: shotgun metagenomic sequencing of stool unveils pathogenic players in HIV-infected children with non-malarial febrile illness

超越发热:粪便宏基因组测序揭示了感染 HIV 的儿童非疟疾发热疾病中的致病因素

Nabisubi, Patricia; Kanyerezi, Stephen; Kebirungi, Grace; Sserwadda, Ivan; Nsubuga, Mike; Kisitu, Grace; Nahirya, Patricia Ntege; Mulindwa, Bonny; Akabwai, George P; Nantongo, Sylvia; Kekitiinwa, Adeodata; Kigozi, Edgar; Luutu, Nsubuga Moses; Katabazi, Fred Ashaba; Kalema, Leymon; Katabalwa, Andrew; Jjingo, Daudi; Mboowa, Gerald

Novel and optimized diagnostics for pediatric TB in endemic countries: NOD-pedFEND study protocol

针对流行地区儿童结核病的新型优化诊断方法:NOD-pedFEND 研究方案

Song, Rinn; Bijker, Else Margreet; Kisitu, Grace; Douglass, Emily; Nasinghe, Emmanuel; Basile, Francesca Wanda; Khambati, Nisreen; Penn-Nicholson, Adam; Ruhwald, Morten; Kim, Soyeon; Mudrak, Nathan; Dendukuri, Nandini; Ugarte-Gil, César; Salgame, Padmini; Alland, David; Dorman, Susan E; Ellner, Jerrold; Joloba, Moses; Kekitiinwa, Adeodata

BREATHER Plus clinical trial design: A randomised non-inferiority trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily ART in virologically suppressed adolescents living with HIV aged 12 to <20 years in sub-Saharan Africa

BREATHER Plus 临床试验设计:一项随机非劣效性试验,旨在评估短周期(用药五天,停药两天)基于多替拉韦/替诺福韦的三联抗逆转录病毒疗法 (ART) 与每日 ART 相比,在撒哈拉以南非洲地区 12 至 20 岁以下 HIV 感染青少年中,病毒学抑制的疗效、安全性和可接受性。

Katongole, Fredrick; Arumugam, Tiyara; Jennings, Angus; Mutata, Constantine; Ssebunya, Patrick; Wamboi, Charity; Green, Alexandra; Bwakura-Dangarembizi, Mutsa; Kityo, Cissy; Siika, Abraham; Archary, Moherndran; Jafta, Lungile; Namukwaya, Stella; Seeley, Janet; Mugerwa, Henry; Walker, Simon; Apoto, Naomi; Thomason, Margaret J; Ford, Deborah; Pett, Sarah L; Kekitiinwa, Adeodata R

Once-daily dolutegravir/lamivudine fixed-dose formulations in children living with HIV: a pharmacokinetic and safety sub-study nested in the open-label, multicentre, randomised, non-inferiority D3/PENTA 21 trial

在 HIV 感染儿童中每日一次服用多替拉韦/拉米夫定固定剂量制剂:一项嵌套于开放标签、多中心、随机、非劣效性 D3/PENTA 21 试验中的药代动力学和安全性子研究

Bevers, Lisanne A H; Toledo, Gabriela; Kisekka, Muzamil; Kaudha, Elizabeth; Ahimbisibwe, Grace M; Deprez, Isabelle; Arumugan, Tiyara; Variava, Ebrahim; Violari, Avy; White, Iona; Bbuye, Dickson; Nanduudu, Annet; Mulwanyi, Enoch; Amuge, Pauline; Rutebarika, Diana A; Kekitiinwa, Adeodata; Kityo, Cissy; Musoke, Philippa; Archary, Moherndran; Boles, Justine; Thomason, Margaret J; de Wildt, Saskia N; Giaquinto, Carlo; Colbers, Angela; Burger, David M; Buchanan, Ann M; Chan, Man K; Jacobs, Tom G; Turkova, Anna

The time is now to use the tools we have to end AIDS in children

现在是时候利用我们现有的工具来终结儿童艾滋病了。

Vojnov, Lara; Shapiro, Roger L; Mulenga, Lloyd B; Kikitiinwa, Adeodata R; Vrazo, Alexandra C; Ekouévi, Patricia Fassinou; Dindi, Nelly Pato; Tiam, Appolinaire; Persaud, Deborah; Mofenson, Lynne

HIV-1 reservoir size after neonatal antiretroviral therapy and the potential to evaluate antiretroviral-therapy-free remission (IMPAACT P1115): a phase 1/2 proof-of-concept study

新生儿抗逆转录病毒治疗后HIV-1病毒库大小及评估无需抗逆转录病毒治疗即可缓解的可能性(IMPAACT P1115):一项1/2期概念验证研究

Persaud, Deborah; Bryson, Yvonne; Nelson, Bryan S; Tierney, Camlin; Cotton, Mark F; Coletti, Anne; Jao, Jennifer; Spector, Stephen A; Mirochnick, Mark; Capparelli, Edmund V; Costello, Diane; Szewczyk, Joseph; Nicodimus, Nicol; Stranix-Chibanda, Lynda; Kekitiinwa, Adeodata R; Korutaro, Violet; Reding, Christina; Carrington, Mary N; Majji, Sai; Yin, Dwight E; Jean-Philippe, Patrick; Chadwick, Ellen G

Long-term non-progression and risk factors for disease progression among children living with HIV in Botswana and Uganda: A retrospective cohort study

博茨瓦纳和乌干达艾滋病毒感染儿童的长期非进展情况及疾病进展风险因素:一项回顾性队列研究

Kyobe, Samuel; Kisitu, Grace; Mwesigwa, Savannah; Farirai, John; Katagirya, Eric; Retshabile, Gaone; Williams, Lesedi; Mirembe, Angela; Ketumile, Lesego; Wayengera, Misaki; Mukisa, John; Sebetso, Gaseene; Diphoko, Thabo; Amujal, Marion; Kigozi, Edgar; Katabazi, Fred; Oceng, Ronald; Mlotshwa, Busisiwe; Morapedi, Koketso; Nsangi, Betty; Wampande, Edward; Tsimako, Masego; Brown, Chester; Kasvosve, Ishmael; Joloba, Moses; Anabwani, Gabriel; Mpoloka, Sununguko; Mardon, Graeme; Kekitiinwa, Adeodata; Hanchard, Neil A; Kyosiimire-Lugemwa, Jacqueline; Matshaba, Mogomotsi; Kiragga, Dithan

Patient characteristics and predictors of mortality among children hospitalised with tuberculosis: A six-year case series study in Uganda

乌干达一项为期六年的病例系列研究:结核病住院患儿的患者特征和死亡率预测因素

Amuge, Pauline Mary; Becker, Greta Lassance; Ssebunya, Rogers Nelson; Nalumansi, Esther; Adaku, Alex; Juma, Michael; Jackson, Jay Brooks; Kekitiinwa, Adeodata Rukyarekere; Elyanu, Peter James; Wobudeya, Eric; Blount, Robert