日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthesis and Application of Bioactive N-Functionalized Aziridines

生物活性N-功能化氮丙啶的合成与应用

Tan, Hao; Samanta, Samya; Qiu, Nan; Adibekian, Alexander; Powers, David C

Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation

鉴定对金黄色葡萄球菌毒力和生物膜形成至关重要的丝氨酸水解酶的共价抑制剂

Upadhyay, Tulsi; Woods, Emily C; Dela Ahator, Stephen; Julin, Kjersti; Faucher, Franco F; Uddin, Md Jalal; Hollander, Marijn J; Pedowitz, Nichole J; Abegg, Daniel; Hammond, Isabella; Eke, Ifeanyichukwu E; Wang, Sijie; Chen, Shiyu; Bennett, John M; Jo, Jeyun; Lentz, Christian S; Adibekian, Alexander; Fellner, Matthias; Bogyo, Matthew

Unveiling cellular communications through rapid pan-membrane-protein labeling.

通过快速泛膜蛋白标记揭示细胞通讯

Gunasekara Hirushi, Cheng Yu-Shiuan, Perez-Silos Vanessa, Zevallos-Morales Alejandro, Abegg Daniel, Burgess Alyssa, Gong Liang-Wei, Minshall Richard D, Adibekian Alexander, Murga-Zamalloa Carlos, Ondrus Alison E, Hu Ying S

Ketoboronate as a Minimal Covalent-Reversible Tag for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

酮硼酸酯作为一种最小的共价可逆标签,用于靶向溶酶体降解细胞外和膜蛋白

Pechalrieu, Dany; Nogueira, Veronique; Qiu, Nan; Racioppo, Brittney; Abegg, Daniel; Hay, Nissim; Adibekian, Alexander

Total Synthesis of (-)-Neocucurbol C Enabled by Pattern Recognition and MHAT Cyclization

利用模式识别和MHAT环化反应实现(-)-新葫芦醇C的全合成

Zhong, Li-Ping; Gudeman, Cyrus; Zhen, Jingsong; Wanasinghe, Oshani A; Hellmig, Jacob; Collins, Michael J E; Bacsa, John; Adibekian, Alexander; Dai, Mingji

Chemoproteomics-Enabled De Novo Proteolysis Targeting Chimera Discovery Platform Identifies a Metallothionein Degrader to Probe Its Role in Cancer

化学蛋白质组学赋能的从头蛋白水解靶向嵌合体发现平台鉴定出一种金属硫蛋白降解酶,用于探究其在癌症中的作用

Racioppo, Brittney; Pechalrieu, Dany; Abegg, Daniel; Dwyer, Brendan; Ramseier, Neal Thomas; Hu, Ying S; Adibekian, Alexander

Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide

利用光开关脂肽实现蛋白酶体蛋白降解的光学控制

Morstein, Johannes; Amatuni, Alexander; Shuster, Anton; Kuttenlochner, Wolfgang; Ko, Tongil; Abegg, Daniel; Groll, Michael; Adibekian, Alexander; Renata, Hans; Trauner, Dirk H

Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera

通过使用靶向核糖核酸酶嵌合体靶向其结构化mRNA来降低固有无序蛋白α-突触核蛋白的水平

Tong, Yuquan; Zhang, Peiyuan; Yang, Xueyi; Liu, Xiaohui; Zhang, Jie; Grudniewska, Magda; Jung, Ikrak; Abegg, Daniel; Liu, Jun; Childs-Disney, Jessica L; Gibaut, Quentin M R; Haniff, Hafeez S; Adibekian, Alexander; Mouradian, M Maral; Disney, Matthew D

Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

混合烷基/芳基膦酸酯可识别代谢丝氨酸水解酶作为抗疟靶点

John M Bennett ,Sunil K Narwal ,Stephanie Kabeche ,Daniel Abegg ,Vandana Thathy ,Fiona Hackett ,Tomas Yeo ,Veronica L Li ,Ryan Muir ,Franco Faucher ,Scott Lovell ,Michael J Blackman ,Alexander Adibekian ,Ellen Yeh ,David A Fidock ,Matthew Bogyo

Chemoproteomic Profiling Maps Zinc-Dependent Cysteine Reactivity

化学蛋白质组学分析揭示锌依赖性半胱氨酸反应性

Qiu, Nan; Pechalrieu, Dany; Abegg, Daniel; Adibekian, Alexander