日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell analysis highlights the significance of malignant cell IFN/MHC-II for immunotherapy response in head and neck squamous cell carcinoma

单细胞分析凸显了恶性细胞IFN/MHC-II在头颈部鳞状细胞癌免疫治疗反应中的重要性

Mints, Michael; Sample, Reilly A; Parikh, Anuraag S; Zaretsky, Jesse M; Qi, Zongtai; Law, Travis; Wang, Fudong; Barrett, Thomas F; Mullins, Riley; Reeb, Ashley; Greenwald, Alissa C; Stoller, Emily; Ramadan, Salma; Gerndt, Sophie; Oppelt, Peter; Ley, Jessica; Thorstad, Wade; Paniello, Randal C; Rich, Jason T; Harbison, Richard A; Zolkind, Paul A; Jackson, Ryan S; Pipkorn, Patrik; Adkins, Douglas R; Uppaluri, Ravindra; Tirosh, Itay; Puram, Sidharth V

Amivantamab for Recurrent or Metastatic Adenoid Cystic Carcinoma: A Phase 2 Nonrandomized Clinical Trial

阿米万单抗治疗复发性或转移性腺样囊性癌:一项 II 期非随机临床试验

Hanna, Glenn J; Zamulko, Olga Y; Grover, Punita; Adkins, Douglas R; Oppelt, Peter J; Romano, Audrey E; Lehn, Maria A; Bachmann, Lindsey M; Wikenheiser-Brokamp, Kathryn A; Lemmon, Christopher A; Forsythe, Allison J; Allen, Casey L; Pan, Jianmin; Rai, Shesh N; El-Gamal, Dalia; Wise-Draper, Trisha M

Nanoparticle Albumin-Bound Paclitaxel and Nivolumab for PD-1 Inhibitor-Refractory Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma

纳米颗粒白蛋白结合型紫杉醇和纳武利尤单抗治疗PD-1抑制剂难治性复发或转移性头颈部鳞状细胞癌

Adkins, Douglas; Ley, Jessica C; Auberle, Christine; Knapp, Brendan; Zaretsky, Jesse; Liu, Jingxia; Oppelt, Peter

Development and validation of the Immune Profile Score (IPS), a novel multiomic algorithmic assay for stratifying outcomes in a real-world cohort of patients with advanced solid cancer treated with immune checkpoint inhibitors

开发和验证免疫谱评分(IPS),一种用于对接受免疫检查点抑制剂治疗的晚期实体瘤患者的真实世界队列进行结果分层的新型多组学算法检测

Zander, Alia D; Erbe, Rossin; Liu, Yan; Jin, Ailin; Hyun, Seung Won; Mukhopadhyay, Sayantoni; Terdich, Ben; Rosasco, Mario G; Patel, Nirali; Mahon, Brett M; Sasser, A Kate; Ting-Lin, Michelle A; Nimeiri, Halla; Guinney, Justin; Adkins, Douglas; Zibelman, Matthew; Beauchamp, Kyle A; Sangli, Chithra; Stein, Michelle M; Taxter, Timothy; Chan, Timothy; Patel, Sandip P; Cohen, Ezra E W

Neoadjuvant Chemotherapy and Surgery versus Surgery for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma: ECOG-ACRIN EA3163

新辅助化疗联合手术与器官保留手术治疗T3和T4a期鼻及鼻窦鳞状细胞癌的比较:ECOG-ACRIN EA3163

Saba, Nabil F; Flamand, Yael; Lin, Derrick T; Chung, Christine H; McDonald, Mark W; Flampouri, Styliani; Khan, Saad A; Snyderman, Carl H; Hanna, Ehab Y; El-Sayed, Ivan H; Solares, Clementino A; Le, Christopher H; Ghaly, Maged; Hwang, Peter H; Shin, Dong M; Axelrod, Rita S; Ikpeazu, Chukwuemeka V; Adkins, Douglas R; Duan, Fenghai; Cohen, Marc; Samuels, Michael A; Swiecicki, Paul L; Subramaniam, Rathan M; Chakravarthy, A Bapsi; Burtness, Barbara A

Palbociclib, a Selective CDK4/6 Inhibitor, Administered Before and After Chemoradiotherapy for Human Papillomavirus-Negative, Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm, Phase II Trial

帕博西尼(一种选择性 CDK4/6 抑制剂)在人乳头瘤病毒阴性、局部晚期头颈部鳞状细胞癌的放化疗前后给药:一项单臂 II 期试验

Oppelt, Peter J; Ley, Jessica C; Puram, Sidharth V; Jackson, Ryan S; Paniello, Randall C; Rich, Jason T; Pipkorn, Patrik; Liu, Jingxia; Thorstad, Wade L; Adkins, Douglas R

Tazemetostat, a Selective EZH2 Inhibitor, in Combination with Pembrolizumab for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Phase 1 Trial

选择性 EZH2 抑制剂 Tazemetostat 与 Pembrolizumab 联合治疗复发性或转移性头颈部鳞状细胞癌:一项 1 期试验

Oppelt, Peter J; Puram, Sidharth V; Liu, Jingxia; Ley, Jessica C; Adkins, Douglas

Mitomycin-C for HPV-Positive and HPV-Negative Platinum-Refractory, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Phase 2 Trial

丝裂霉素C治疗HPV阳性和HPV阴性铂类耐药、复发或转移性头颈部鳞状细胞癌:一项II期试验

Oppelt, Peter; Ley, Jessica; Auberle, Christine; Knapp, Brendan; Zaretsky, Jesse; Wan, Fei; Adkins, Douglas

LiGeR-HN phase III trials of petosemtamab + pembrolizumab and petosemtamab monotherapy in recurrent or metastatic HNSCC

LiGeR-HN III期临床试验评估了petosemtamab联合pembrolizumab和petosemtamab单药治疗复发或转移性头颈部鳞状细胞癌(HNSCC)的疗效。

Machiels, Jean-Pascal; Fayette, Jérôme; Haddad, Robert; Adkins, Douglas; Gillison, Maura; Harrington, Kevin J; Kim, Sung-Bae; Le Tourneau, Christophe; Psyrri, Amanda; Rosenberg, Ari; Siu, Lillian L; Tahara, Makoto; William, William N Jr; Ford, Jim; Jauhari, Shekeab; Pyle, Rebecca; Shen, Yu-Ming; Yao, David; Zohren, Fabian; Vokes, Everett

Olaparib, Pembrolizumab, and Carboplatin as First-Line Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Phase II Trial

奥拉帕尼、帕博利珠单抗和卡铂作为复发或转移性头颈部鳞状细胞癌一线治疗:一项 II 期试验

Adkins, Douglas; Ley, Jessica C; Liu, Jingxia; Oppelt, Peter