文献库，生知库 | 链接生命科学的每一步

Milica Vulin ，Charly Jehanno ，Atul Sethi ，Ana Luísa Correia ，Milan M S Obradović ，Joana Pinto Couto ，Marie-May Coissieux ，Maren Diepenbruck ，Bogdan-Tiberius Preca ，Katrin Volkmann ，Priska Auf der Maur ，Alexander Schmidt ，Simone Münst ，Loïc Sauteur ，Michal Kloc ，Marta Palafox ，Adrian Britschgi ，Vincent Unterreiner ，Olaf Galuba ，Isabelle Claerr ，Sandra Lopez-Romero ，Giorgio G Galli ，Daniel Baeschlin ，Ryoko Okamoto ，Savas D Soysal ，Robert Mechera ，Walter P Weber ，Thomas Radimerski ，Mohamed Bentires-Alj

乳腺癌

肿瘤

肿瘤免疫

发表日期：2022

文献求助收藏

Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway

细胞对靶向蛋白质降解的抵抗机制与参与的泛素转移途径受损有关

期刊:ACS Chemical Biology

影响因子:3.5

doi:10.1021/acschembio.9b00525

Philipp Ottis, Chiara Palladino, Phillip Thienger, Adrian Britschgi, Christian Heichinger, Marco Berrera, Alice Julien-Laferriere, Filip Roudnicky, Tony Kam-Thong, James R Bischoff, Bruno Martoglio, Piergiorgio Pettazzoni

Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy

低自噬 (ATG) 基因表达与未成熟的 AML 原始细胞表型相关，并可在 AML 分化治疗期间恢复

期刊:Oxidative Medicine and Cellular Longevity

影响因子:

doi:10.1155/2018/1482795

Jing Jin, Adrian Britschgi, Anna M Schläfli, Magali Humbert, Deborah Shan-Krauer, Jasmin Batliner, Elena A Federzoni, Marion Ernst, Bruce E Torbett, Shida Yousefi, Hans-Uwe Simon, Mario P Tschan

The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα

Hippo 激酶 LATS1 和 2 通过与 ERα 相互作用控制人类乳腺细胞命运

期刊:Nature

影响因子:50.5

doi:10.1038/nature20829

Adrian Britschgi, Stephan Duss, Sungeun Kim, Joana Pinto Couto, Heike Brinkhaus, Shany Koren, Duvini De Silva, Kirsten D Mertz, Daniela Kaup, Zsuzsanna Varga, Hans Voshol, Alexandra Vissieres, Cedric Leroy, Tim Roloff, Michael B Stadler, Christina H Scheel, Loren J Miraglia, Anthony P Orth, Ghislain

Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation

通过蛋白质组学筛选结合双分子荧光互补技术鉴定新型死亡相关蛋白激酶 2 相互作用伙伴

期刊:Molecular and Cellular Biology

影响因子:3.2

doi:10.1128/MCB.00515-15

Barbara Geering, Zina Zokouri, Samuel Hürlemann, Bertran Gerrits, David Ausländer, Adrian Britschgi, Mario P Tschan, Hans-Uwe Simon, Martin Fussenegger

信号转导

发表日期：2015

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Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation

自噬诱导是全反式维甲酸诱导白血病细胞分化的关键环节，也是药物调节的潜在靶点

期刊:Experimental Hematology

影响因子:2.5

doi:10.1016/j.exphem.2015.04.012

Nina Orfali, Tracey R O'Donovan, Michelle J Nyhan, Adrian Britschgi, Mario P Tschan, Mary R Cahill, Nigel P Mongan, Lorraine J Gudas, Sharon L McKenna

Mesenchymal precursor cells maintain the differentiation and proliferation potentials of breast epithelial cells

间充质前体细胞维持乳腺上皮细胞的分化和增殖潜能

期刊:Breast Cancer Research

影响因子:6.1

doi:10.1186/bcr3673

Stephan Duss, Heike Brinkhaus, Adrian Britschgi, Erik Cabuy, Daniel M Frey, Dirk J Schaefer, Mohamed Bentires-Alj

The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL

肿瘤抑制基因 DAPK2 在粒细胞分化过程中由髓系转录因子 PU.1 和 C/EBPα 诱导，但在 APL 中受 PML-RARα 抑制

期刊:Journal of Leukocyte Biology

影响因子:3.6

doi:10.1189/jlb.1112608

Magali Humbert, Elena A Federzoni, Adrian Britschgi, Anna M Schläfli, Peter J M Valk, Thomas Kaufmann, Torsten Haferlach, Gerhard Behre, Hans-Uwe Simon, Bruce E Torbett, Martin F Fey, Mario P Tschan

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

钙激活氯通道 ANO1 通过激活 EGFR 和 CAMK 信号促进乳腺癌进展

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1217072110

Adrian Britschgi, Anke Bill, Heike Brinkhaus, Christopher Rothwell, Ieuan Clay, Stephan Duss, Michael Rebhan, Pichai Raman, Chantale T Guy, Kristie Wetzel, Elizabeth George, M Oana Popa, Sarah Lilley, Hedaythul Choudhury, Martin Gosling, Louis Wang, Stephanie Fitzgerald, Jason Borawski, Jonathan Baf

A high-throughput drug screen reveals means to differentiate triple-negative breast cancer

高通量药物筛选揭示了区分三阴性乳腺癌的方法

Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway

细胞对靶向蛋白质降解的抵抗机制与参与的泛素转移途径受损有关

Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy

低自噬 (ATG) 基因表达与未成熟的 AML 原始细胞表型相关，并可在 AML 分化治疗期间恢复

The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα

Hippo 激酶 LATS1 和 2 通过与 ERα 相互作用控制人类乳腺细胞命运

Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation

通过蛋白质组学筛选结合双分子荧光互补技术鉴定新型死亡相关蛋白激酶 2 相互作用伙伴

Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation

自噬诱导是全反式维甲酸诱导白血病细胞分化的关键环节，也是药物调节的潜在靶点

Mesenchymal precursor cells maintain the differentiation and proliferation potentials of breast epithelial cells

间充质前体细胞维持乳腺上皮细胞的分化和增殖潜能

The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL

肿瘤抑制基因 DAPK2 在粒细胞分化过程中由髓系转录因子 PU.1 和 C/EBPα 诱导，但在 APL 中受 PML-RARα 抑制

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

钙激活氯通道 ANO1 通过激活 EGFR 和 CAMK 信号促进乳腺癌进展