日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4

BRD4 与 ASXL1 基因组靶标的结合依赖于 BRD4 的末端外结构域。

Selvam, Karthik; Lu, Shuang; Messmer, Clémence; Pang, Yakun; Biswas, Soumi; Khalil, Moustafa; Zhang, Peng; Tulaiha, Rima; Zhou, Ming-Ming; Kitamura, Toshio; Lauberth, Shannon M; Blanco, M Andres; Yang, Feng-Chun; Affar, El Bachir; Zhao, Zibo; Zeng, Lei; Wang, Lu; Kutateladze, Tatiana G

A tryptophan-phenylalanine binding motif for the histone methyltransferases MLL4 and MLL3

组蛋白甲基转移酶 MLL4 和 MLL3 的色氨酸-苯丙氨酸结合基序

Biswas, Soumi; Tavaf, Zohreh; Benz, Caroline; Khalil, Moustafa; Becht, Dustin C; Simonetti, Leandro; Blanco, M Andres; Affar, El Bachir; Ivarsson, Ylva; Kutateladze, Tatiana G

O-GlcNAcylation of FOXK1 co-opts BAP1 to orchestrate the E2F pathway and promotes oncogenesis.

FOXK1 的 O-GlcNAc 化可与 BAP1 协同作用,调控 E2F 通路,促进肿瘤发生

Ahmed Oumaima, Masclef Louis, Iannantuono Nicholas, Gagnon Jessica, Gushul-Leclaire Mila, Boulay Karine, Estavoyer Benjamin, Echbicheb Mohamed, Ali Boubacar Kalidou, Poy Marty, Boubekeur Amina, Menggad Saad, Schcolnik-Cabrera Alejandro, Balsalobre Aurelio, Bonneil Eric, Thibault Pierre, Hulea Laura, Mallette Frédérick A, Drouin Jacques, Tanaka Yoshiaki, Affar El Bachir

IKAROS: from chromatin organization to transcriptional elongation control

IKAROS:从染色质组织到转录延伸调控

Affar, Malik; Bottardi, Stefania; Quansah, Norreen; Lemarié, Maud; Ramón, Ailyn C; Affar, El Bachir; Milot, Eric

Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300.

EZH2 的多个转录激活结构域与 p300 的 TAZ2 结构域结合,并刺激 p300 的乙酰转移酶功能

Becht Dustin C, Biswas Soumi, Xu Chenxi, Xuan Hongwen, Khalil Moustafa, Cai Ling, Musselman Catherine A, Liu Xin, Affar El Bachir, Shi Xiaobing, Wang Gang Greg, Kutateladze Tatiana G

Colorectal cancer hot spot mutations attenuate the ASXL-MLL4 interaction.

结直肠癌热点突变减弱了 ASXL-MLL4 相互作用

Biswas Soumi, Lee Ji-Eun, Xie Guojia, Masclef Louis, Ren Zhizhong, Côté Jacques, Affar El Bachir, Ge Kai, Kutateladze Tatiana G

MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes

MNDA,一种参与白细胞转录调控和凋亡控制的PYHIN因子

Bottardi, Stefania; Layne, Taylorjade; Ramòn, Ailyn C; Quansah, Norreen; Wurtele, Hugo; Affar, El Bachir; Milot, Eric

An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes

泛素化与其他翻译后修饰在调控细胞过程中相互作用的清单

Barbour, Haithem; Nkwe, Nadine Sen; Estavoyer, Benjamin; Messmer, Clémence; Gushul-Leclaire, Mila; Villot, Romain; Uriarte, Maxime; Boulay, Karine; Hlayhel, Sari; Farhat, Bassel; Milot, Eric; Mallette, Frédérick A; Daou, Salima; Affar, El Bachir

Mechanisms orchestrating the enzymatic activity and cellular functions of deubiquitinases

调控去泛素化酶的酶活性和细胞功能的机制

Estavoyer, Benjamin; Messmer, Clémence; Echbicheb, Mohamed; Rudd, Christopher E; Milot, Eric; Affar, El Bachir

USP42 deubiquitinase in the arena of liquid-liquid phase separation and nuclear speckles

USP42 去泛素化酶在液-液相分离和核斑点领域

Uriarte, Maxime; Milot, Eric; Affar, El Bachir