日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of an RNAi therapeutic for alpha-1-antitrypsin liver disease

开发用于治疗 α-1-抗胰蛋白酶肝病的 RNAi 疗法

Christine I Wooddell, Keith Blomenkamp, Ryan M Peterson, Vladimir M Subbotin, Christian Schwabe, James Hamilton, Qili Chu, Dawn R Christianson, Julia O Hegge, John Kolbe, Holly L Hamilton, Maria F Branca-Afrazi, Bruce D Given, David L Lewis, Edward Gane, Steven B Kanner, Jeffrey H Teckman

Understanding the Value of Tumor Markers in Pediatric Ovarian Neoplasms

了解肿瘤标志物在儿童卵巢肿瘤中的价值

Lawrence, Amy E; Fallat, Mary E; Hewitt, Geri; Hertweck, Paige; Onwuka, Amanda; Afrazi, Amin; Bence, Christina; Burns, Robert C; Corkum, Kristine S; Dillon, Patrick A; Ehrlich, Peter F; Fraser, Jason D; Gonzalez, Dani O; Grabowski, Julia E; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Overman, R Elliott; Rademacher, Brooks L; Raiji, Manish T; Sato, Thomas T; Scannell, Madeline; Sujka, Joseph A; Wright, Tiffany; Minneci, Peter C; Deans, Katherine J; Aldrink, Jennifer H

Gut Symbionts Lactobacillus reuteri R2lc and 2010 Encode a Polyketide Synthase Cluster That Activates the Mammalian Aryl Hydrocarbon Receptor

肠道共生菌罗伊氏乳杆菌 R2lc 和 2010 编码可激活哺乳动物芳烃受体的聚酮合酶簇

Mustafa Özçam, Restituto Tocmo, Jee-Hwan Oh, Amin Afrazi, Joshua D Mezrich, Stefan Roos, Jan Claesen, Jan-Peter van Pijkeren

Differential effects of diesel exhaust particles on T cell differentiation and autoimmune disease

柴油机尾气颗粒对 T 细胞分化和自身免疫疾病的不同影响

Chelsea A O'Driscoll, Leah A Owens, Madeline E Gallo, Erica J Hoffmann, Amin Afrazi, Mei Han, John H Fechner, James J Schauer, Christopher A Bradfield, Joshua D Mezrich

Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

母乳通过激活表皮生长因子受体抑制肠上皮细胞中的 Toll 样受体 4,从而预防坏死性小肠结肠炎的发生。

Good, M; Sodhi, C P; Egan, C E; Afrazi, A; Jia, H; Yamaguchi, Y; Lu, P; Branca, M F; Ma, C; Prindle, T Jr; Mielo, S; Pompa, A; Hodzic, Z; Ozolek, J A; Hackam, D J

Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis

Toll样受体4介导的肠隐窝内质网应激可诱发坏死性小肠结肠炎

Afrazi, Amin; Branca, Maria F; Sodhi, Chhinder P; Good, Misty; Yamaguchi, Yukihiro; Egan, Charlotte E; Lu, Peng; Jia, Hongpeng; Shaffiey, Shahab; Lin, Joyce; Ma, Congrong; Vincent, Garrett; Prindle, Thomas Jr; Weyandt, Samantha; Neal, Matthew D; Ozolek, John A; Wiersch, John; Tschurtschenthaler, Markus; Shiota, Chiyo; Gittes, George K; Billiar, Timothy R; Mollen, Kevin; Kaser, Arthur; Blumberg, Richard; Hackam, David J

A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis

TLR4 诱导自噬在调节肠细胞迁移和坏死性小肠结肠炎发病机制中起关键作用

Matthew D Neal, Chhinder P Sodhi, Mitchell Dyer, Brian T Craig, Misty Good, Hongpeng Jia, Ibrahim Yazji, Amin Afrazi, Ward M Richardson, Donna Beer-Stolz, Congrong Ma, Thomas Prindle, Zachary Grant, Maria F Branca, John Ozolek, David J Hackam

Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors

发现并验证一类新型小分子 Toll 样受体 4 (TLR4) 抑制剂

Matthew D Neal, Hongpeng Jia, Benjamin Eyer, Misty Good, Christopher J Guerriero, Chhinder P Sodhi, Amin Afrazi, Thomas Prindle Jr, Congrong Ma, Maria Branca, John Ozolek, Jeffrey L Brodsky, Peter Wipf, David J Hackam

Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling

内皮 TLR4 激活通过 eNOS-NO-亚硝酸盐信号传导损害坏死性小肠结肠炎的肠道微循环灌注

Ibrahim Yazji, Chhinder P Sodhi, Elizabeth K Lee, Misty Good, Charlotte E Egan, Amin Afrazi, Matthew D Neal, Hongpeng Jia, Joyce Lin, Congrong Ma, Maria F Branca, Thomas Prindle, Ward M Richardson, John Ozolek, Timothy R Billiar, David G Binion, Mark T Gladwin, David J Hackam

Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice

肠道上皮细胞 Toll 样受体 4 调控杯状细胞发育,并且是小鼠坏死性小肠结肠炎所必需的。

Sodhi, Chhinder P; Neal, Matthew D; Siggers, Richard; Sho, Shonan; Ma, Congrong; Branca, Maria F; Prindle, Thomas Jr; Russo, Anthony M; Afrazi, Amin; Good, Misty; Brower-Sinning, Rachel; Firek, Brian; Morowitz, Michael J; Ozolek, John A; Gittes, George K; Billiar, Timothy R; Hackam, David J