日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Continuous replenishment of the dysfunctional CD8 T cell axis is associated with response to chemoimmunotherapy in advanced breast cancer.

持续补充功能失调的 CD8 T 细胞轴与晚期乳腺癌化疗免疫疗法的疗效相关

Metoikidou Christina, Karnaukhov Vadim, Boeckx Bram, Timperi Eleonora, Bonté Pierre-Emmanuel, Wang Ling, Espenel Marion, Albaud Benoit, Loirat Delphine, Wang Xiaoxiao, Sotiriou Christos, Aftimos Philippe, Punie Kevin, Wildiers Hans, Labroska Viktorija, Wang Ming-Wei, Waterfall Joshua J, Piccart-Gebhart Martine, Mora Thierry, Walczak Aleksandra, Lantz Olivier, Buisseret Laurence, Lambrechts Diether, Amigorena Sebastian, Romano Emanuela

Economic Evaluation of Comprehensive Genomic Profiling in an Advanced Solid Cancer Population

晚期实体瘤人群综合基因组分析的经济评价

van Schaik, Lucas F; Maes, Brigitte; Volders, Pieter-Jan; Froyen, Guy; Aftimos, Philippe; de Azambuja, Evandro; Blommestein, Hedwig M; van Harten, Wim H; Retèl, Valesca P

A nationwide comprehensive genomic profiling and molecular tumor board platform for patients with advanced cancer

面向晚期癌症患者的全国性综合基因组分析和分子肿瘤委员会平台

Volders, Pieter-Jan; Aftimos, Philippe; Dedeurwaerdere, Franceska; Martens, Geert; Canon, Jean-Luc; Beniuga, Gabriela; Froyen, Guy; Van Huysse, Jacques; De Pauw, Rebecca; Prenen, Hans; Lambin, Suzan; Decoster, Lore; Vaeyens, Freya; Rottey, Sylvie; Van Dam, Pieter-Jan; Decoster, Lynn; Rutten, Annemie; Schreuer, Max; Loontiens, Siebe; Van der Meulen, Joni; Mebis, Jeroen; Cuppens, Kristof; Tejpar, Sabine; Vanden Bempt, Isabelle; De Grève, Jacques; Schröder, David; van Marcke, Cédric; Van Den Bulcke, Marc; de Azambuja, Evandro; Punie, Kevin; Maes, Brigitte

Imlunestrant, an oral selective estrogen receptor degrader, in combination with HER2 directed therapy, with or without abemaciclib, in ER-positive, HER2-positive advanced breast cancer: results from the phase 1a/1b EMBER study

伊姆鲁司群(一种口服选择性雌激素受体降解剂)联合HER2靶向治疗,无论是否联合阿贝西利,用于治疗ER阳性、HER2阳性晚期乳腺癌:来自EMBER 1a/1b期研究的结果

Bhave, Manali; Jhaveri, Komal L; Kaufman, Peter A; Aftimos, Philippe; Lombard, Janine; Giridhar, Karthik V; Im, Seock-Ah; Ma, Cynthia X; Lee, Kuo-Ting; Kim, Sung-Bae; Sohn, Joohyuk; Li, Yujia; Yuen, Eunice; Estrem, Shawn T; Nguyen, Bastien; Makena, Monish Ram; Ismail-Khan, Roohi; Beeram, Muralidhar

Complete remission with olaparib in BRIP1-mutated metastatic high-grade pleomorphic sarcoma: case study and literature review - an example of a genomic profiling-based tumor treatment, in a cancer type with high unmet clinical need

奥拉帕尼治疗BRIP1突变转移性高级别多形性肉瘤实现完全缓解:病例研究和文献综述——基于基因组分析的肿瘤治疗案例,针对一种临床需求未被满足的癌症类型

Thooft, Alexander D J; Joris, Sofie; Jacobs, Celine; Creytens, David; Rottey, Sylvie; Maes, Brigitte; Aftimos, Philippe; Lapeire, Lore

Imlunestrant, an Oral Selective Estrogen Receptor Degrader, as Monotherapy and in Combination With Targeted Therapy in Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Phase Ia/Ib EMBER Study

伊姆伦司群(一种口服选择性雌激素受体降解剂)单药治疗及联合靶向治疗在雌激素受体阳性、人表皮生长因子受体2阴性晚期乳腺癌中的疗效:EMBER Ia/Ib期研究

Jhaveri, Komal L; Lim, Elgene; Jeselsohn, Rinath; Ma, Cynthia X; Hamilton, Erika P; Osborne, Cynthia; Bhave, Manali; Kaufman, Peter A; Beck, J Thaddeus; Manso Sanchez, Luis; Parajuli, Ritesh; Wang, Hwei-Chung; Tao, Jessica J; Im, Seock-Ah; Harnden, Kathleen; Yonemori, Kan; Dhakal, Ajay; Neven, Patrick; Aftimos, Philippe; Pierga, Jean-Yves; Lu, Yen-Shen; Larson, Timothy; Jerez, Yolanda; Sideras, Kostandinos; Sohn, Joohyuk; Kim, Sung-Bae; Saura, Cristina; Bardia, Aditya; Sammons, Sarah L; Bacchion, Francesca; Li, Yujia; Yuen, Eunice; Estrem, Shawn T; Rodrik-Outmezguine, Vanessa; Nguyen, Bastien; Ismail-Khan, Roohi; Smyth, Lillian; Beeram, Muralidhar

A Preoperative Window-of-Opportunity Study of Oral SERD, Imlunestrant, in Newly Diagnosed ER-Positive, HER2-Negative Early Breast Cancer: Results from the EMBER-2 Study

一项针对新诊断的ER阳性、HER2阴性早期乳腺癌患者的术前机会窗口研究:口服选择性雌激素受体拮抗剂(SERD)伊姆伦司群的疗效:EMBER-2研究结果

Neven, Patrick; Stahl, Nicole; Vidal, Maria; Martín, Miguel; Kaufman, Peter A; Harbeck, Nadia; Hunt, Kelly K; Carter, Stacey; Bidard, Francois-Clement; Fasching, Peter A; Aftimos, Philippe; Wheatley, Duncan; Hamilton, Erika; Aft, Rebecca; Kulkarni, Swati; Schmid, Peter; Bhave, Manali; Ismail-Khan, Roohi; Karacsonyi, Claudia; Estrem, Shawn T; Nguyen, Bastien; Ozbek, Umut; Yuen, Eunice; Rodrik-Outmezguine, Vanessa; Ciruelos, Eva

Molecular imaging predicts lack of T-DM1 response in advanced HER2-positive breast cancer (final results of ZEPHIR trial)

分子影像学预测晚期 HER2 阳性乳腺癌患者对 T-DM1 治疗无反应(ZEPHIR 试验的最终结果)

Mileva, Magdalena; de Vries, Elisabeth G E; Guiot, Thomas; Wimana, Zéna; Deleu, Anne-Leen; Schröder, Carolien P; Lefebvre, Yolene; Paesmans, Marianne; Stroobants, Sigrid; Huizing, Manon; Aftimos, Philippe; Tol, Jolien; Van der Graaf, Winette T A; Oyen, Wim J G; Vugts, Danielle J; Menke-van der Houven van Oordt, C Willemien; Brouwers, Adrienne H; Piccart-Gebhart, Martine; Flamen, Patrick; Gebhart, Géraldine

Avelumab Plus Talazoparib in Patients With BRCA1/2- or ATM-Altered Advanced Solid Tumors: Results From JAVELIN BRCA/ATM, an Open-Label, Multicenter, Phase 2b, Tumor-Agnostic Trial

Avelumab 联合 Talazoparib 治疗 BRCA1/2 或 ATM 基因改变的晚期实体瘤患者:JAVELIN BRCA/ATM 研究结果,一项开放标签、多中心、2b 期、肿瘤类型无关试验

Schram, Alison M; Colombo, Nicoletta; Arrowsmith, Edward; Narayan, Vivek; Yonemori, Kan; Scambia, Giovanni; Zelnak, Amelia; Bauer, Todd M; Jin, Ning; Ulahannan, Susanna V; Colleoni, Marco; Aftimos, Philippe; Donoghue, Mark T A; Rosen, Ezra; Rudneva, Vasilisa A; Telli, Melinda L; Domchek, Susan M; Galsky, Matthew D; Hoyle, Margaret; Chappey, Colombe; Stewart, Ross; Blake-Haskins, John A; Yap, Timothy A

Author Correction: Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial

作者更正:紫杉醇联合卡铂和度伐利尤单抗,加或不加oleclumab,用于治疗既往未接受治疗的局部晚期或转移性三阴性乳腺癌女性患者:SYNERGY I/II期随机试验

Buisseret, Laurence; Loirat, Delphine; Aftimos, Philippe; Maurer, Christian; Punie, Kevin; Debien, Véronique; Kristanto, Paulus; Eiger, Daniel; Goncalves, Anthony; Ghiringhelli, François; Taylor, Donatienne; Clatot, Florent; Van den Mooter, Tom; Ferrero, Jean-Marc; Bonnefoi, Hervé; Canon, Jean-Luc; Duhoux, Francois P; Mansi, Laura; Poncin, Renaud; Barthélémy, Philippe; Isambert, Nicolas; Denis, Zoë; Catteau, Xavier; Salgado, Roberto; Agostinetto, Elisa; de Azambuja, Evandro; Rothé, Françoise; Craciun, Ligia; Venet, David; Romano, Emanuela; Stagg, John; Paesmans, Marianne; Larsimont, Denis; Sotiriou, Christos; Ignatiadis, Michail; Piccart-Gebhart, Martine