日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Pirtobrutinib Versus Ibrutinib in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

吡托布替尼与伊布替尼治疗初治及复发/难治性慢性淋巴细胞白血病/小淋巴细胞淋巴瘤的比较

期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO-25-02477
Woyach, Jennifer A; Qiu, Lugui; Grosicki, Sebastian; Wrobel, Tomasz; Capra, Marcelo; Czyz, Jaroslaw; Yi, Shuhua; Eom, Ki-Seong; Panovská, Anna; Jurczak, Wojciech; Laribi, Kamel; Jacobasch, Lutz; Baker, Ross; Agajanian, Richy; Berkovits, Alejandro; Özcan, Muhit; Lepretre, Stéphane; Coombs, Catherine C; Cramer, Paula; Lewis, Katharine L; Hill, Marisa; Bao, Katherine; Bian, Yuanyuan; De Batista Ribeiro, Silvia Ramalho; Bhandari, Naleen Raj; Ruppert, Amy S; Leow, Ching Ching; Wierda, William G
白血病
细胞生物学
淋巴瘤
发表日期：2026
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The gain-of-function UBE3A(Q588E) variant causes Angelman-like neurodevelopmental phenotypes in mice.

UBE3A(Q588E) 功能获得性变异会导致小鼠出现类似安格曼综合征的神经发育表型

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-92511-w
Weston Kellan P, Gunelson Anna M, Maloney Susan E, Ge Xia, Stelzer Jalin A, Kim Kwang-Soo, Collier Shylyn, Mindt Marissa M, Agajanian Megan J, Major Michael B, Goldfarb Dennis, Noguchi Kevin K, Yi Jason J
神经科学
发表日期：2025
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Acalabrutinib in combination with rituximab and lenalidomide in patients with relapsed or refractory follicular lymphoma: Results of the phase 1b open-label study (ACE-LY-003)

阿卡替尼联合利妥昔单抗和来那度胺治疗复发或难治性滤泡性淋巴瘤患者：1b期开放标签研究（ACE-LY-003）的结果

期刊:British Journal of Haematology
影响因子:3.8
doi:10.1111/bjh.19951
Strati, Paolo; Agajanian, Richy; Lossos, Izidore S; Coleman, Morton; Kridel, Robert; Wood, Andrew; Lesley, Robin; Wun, Chuan-Chuan; Stephens, Deborah M
淋巴瘤
发表日期：2025
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Efficacy, safety, and biomarker analyses of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with advanced non-small cell lung cancer

针对TGF-β和PD-L1的双功能融合蛋白bintrafusp alfa在晚期非小细胞肺癌患者中的疗效、安全性和生物标志物分析

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2023-008480
Rajan, Arun; Abdul Sater, Houssein; Rahma, Osama; Agajanian, Richy; Lassoued, Wiem; Marté, Jennifer L; Tsai, Yo-Ting; Donahue, Renee N; Lamping, Elizabeth; Bailey, Shania; Weisman, Andrew; Walter-Rodriguez, Beatriz; Ito, Rena; Vugmeyster, Yulia; Sato, Masashi; Machl, Andreas; Schlom, Jeffrey; Gulley, James L
肺癌
肿瘤
肿瘤免疫
TGF-β
PD-L1
细胞生物学
发表日期：2024
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Exploring and Learning the Universe of Protein Allostery Using Artificial Intelligence Augmented Biophysical and Computational Approaches

利用人工智能增强的生物物理和计算方法探索和学习蛋白质变构的世界

期刊:Journal of Chemical Information and Modeling
影响因子:5.6
doi:10.1021/acs.jcim.2c01634
Steve Agajanian, Mohammed Alshahrani, Fang Bai, Peng Tao, Gennady M Verkhivker
信号转导
发表日期：2023
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Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study

福斯他替尼治疗温抗体自身免疫性溶血性贫血：一项 II 期多中心开放标签研究

期刊:American Journal of Hematology
影响因子:9.9
doi:10.1002/ajh.26508
Kuter, David J; Rogers, Kerry A; Boxer, Michael A; Choi, Michael; Agajanian, Richy; Arnold, Donald M; Broome, Catherine M; Field, Joshua J; Murakhovskaya, Irina; Numerof, Robert; Tong, Sandra
代谢
贫血
免疫/内分泌
发表日期：2022
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Computer Simulations and Network-Based Profiling of Binding and Allosteric Interactions of SARS-CoV-2 Spike Variant Complexes and the Host Receptor: Dissecting the Mechanistic Effects of the Delta and Omicron Mutations

SARS-CoV-2刺突蛋白变异体复合物与宿主受体结合及变构相互作用的计算机模拟和基于网络的分析：解析Delta和Omicron突变的机制效应

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23084376
Verkhivker, Gennady; Agajanian, Steve; Kassab, Ryan; Krishnan, Keerthi
SARS-CoV-2
信号转导
发表日期：2022
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Probing Mechanisms of Binding and Allostery in the SARS-CoV-2 Spike Omicron Variant Complexes with the Host Receptor: Revealing Functional Roles of the Binding Hotspots in Mediating Epistatic Effects and Communication with Allosteric Pockets

探究SARS-CoV-2刺突蛋白Omicron变体与宿主受体复合物的结合和变构机制：揭示结合热点在介导上位效应和与变构口袋通讯中的功能作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms231911542
Verkhivker, Gennady; Agajanian, Steve; Kassab, Ryan; Krishnan, Keerthi
SARS-CoV-2
信号转导
发表日期：2022
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Interpretable Machine Learning Models for Molecular Design of Tyrosine Kinase Inhibitors Using Variational Autoencoders and Perturbation-Based Approach of Chemical Space Exploration

基于变分自编码器和扰动化学空间探索方法的酪氨酸激酶抑制剂分子设计的可解释机器学习模型

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms231911262
Krishnan, Keerthi; Kassab, Ryan; Agajanian, Steve; Verkhivker, Gennady
信号转导
发表日期：2022
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Integrating Conformational Dynamics and Perturbation-Based Network Modeling for Mutational Profiling of Binding and Allostery in the SARS-CoV-2 Spike Variant Complexes with Antibodies: Balancing Local and Global Determinants of Mutational Escape Mechanisms

整合构象动力学和基于扰动的网络建模，对SARS-CoV-2刺突蛋白变体与抗体的复合物的结合和变构进行突变分析：平衡突变逃逸机制的局部和全局决定因素

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom12070964
Verkhivker, Gennady; Agajanian, Steve; Kassab, Ryan; Krishnan, Keerthi
SARS-CoV-2
发表日期：2022
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