日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte Toxicity

ATP13A2功能丧失驱动的多胺失调导致SAM耗竭和表观遗传星形胶质细胞毒性

Coccia, Elena; Parfitt, Gustavo Morrone; Ijaz, Sundas; Sati, Aisha; Gesner, Julia; Arevalo, Andrea Perez; Strong, Jennifer; Bright, Anna; Sohail, Soha; Meimoun, Thea; Ahfeldt, Tim; Vangheluwe, Peter; Blanchard, Joel

Publisher Correction: A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides

出版商更正:一项利用杀虫剂和iPSC多巴胺能神经元筛选的方法可以识别和分类与帕金森病相关的杀虫剂

Paul, Kimberly C; Krolewski, Richard C; Lucumi Moreno, Edinson; Blank, Jack; Holton, Kristina M; Ahfeldt, Tim; Furlong, Melissa; Yu, Yu; Cockburn, Myles; Thompson, Laura K; Kreymerman, Alexander; Ricci-Blair, Elisabeth M; Li, Yu Jun; Patel, Heer B; Lee, Richard T; Bronstein, Jeff; Rubin, Lee L; Khurana, Vikram; Ritz, Beate

Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity

神经元TIMP2调节海马依赖性可塑性和细胞外基质复杂性

Ferreira, Ana Catarina; Hemmer, Brittany M; Philippi, Sarah M; Grau-Perales, Alejandro B; Rosenstadt, Jacob L; Liu, Hanxiao; Zhu, Jeffrey D; Kareva, Tatyana; Ahfeldt, Tim; Varghese, Merina; Hof, Patrick R; Castellano, Joseph M

Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson's disease

构建与生理相关的帕金森病人类多能干细胞(hPSC)模型

Coccia, Elena; Ahfeldt, Tim

Modeling the complex genetic architectures of brain disease

构建脑疾病复杂遗传结构的模型

Fernando, Michael B; Ahfeldt, Tim; Brennand, Kristen J

Studying human disease using human neurons

利用人类神经元研究人类疾病

Ahfeldt, Tim; Litterman, Nadia K; Rubin, Lee L

Pattern specification and immune response transcriptional signatures of pericardial and subcutaneous adipose tissue

心包和皮下脂肪组织的模式特异性和免疫反应转录特征

Lau, Frank H; Deo, Rahul C; Mowrer, Gregory; Caplin, Joshua; Ahfeldt, Tim; Kaplan, Adam; Ptaszek, Leon; Walker, Jennifer D; Rosengard, Bruce R; Cowan, Chad A

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

利用合成修饰的mRNA对人类细胞进行高效重编程,使其获得多能性和定向分化

Warren Luigi, Manos Philip D, Ahfeldt Tim, Loh Yuin-Han, Li Hu, Lau Frank, Ebina Wataru, Mandal Pankaj K, Smith Zachary D, Meissner Alexander, Daley George Q, Brack Andrew S, Collins James J, Cowan Chad, Schlaeger Thorsten M, Rossi Derrick J

Disease-specific induced pluripotent stem cells

疾病特异性诱导多能干细胞

Park, In-Hyun; Arora, Natasha; Huo, Hongguang; Maherali, Nimet; Ahfeldt, Tim; Shimamura, Akiko; Lensch, M William; Cowan, Chad; Hochedlinger, Konrad; Daley, George Q

A high-efficiency system for the generation and study of human induced pluripotent stem cells.

用于生成和研究人类诱导多能干细胞的高效系统

Maherali Nimet, Ahfeldt Tim, Rigamonti Alessandra, Utikal Jochen, Cowan Chad, Hochedlinger Konrad