日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder

DOT1L 的缺失会扰乱神经元转录,并导致神经发育障碍。

Maroni, Marissa J; Barton, Melissa; Lynch, Katherine; Deshwar, Ashish R; Campbell, Philip D; Millard, Josephine; Lee, Rachel; Cohen, Annastelle; Ahmad, Rili; Paranjapye, Alekh; Faundes, Víctor; Repetto, Gabriela M; McKenna, Caoimhe; Shillington, Amelle L; Phornphutkul, Chanika; Hove, Hanne B; Mancini, Grazia M S; Schot, Rachel; Barakat, Tahsin Stefan; Richmond, Christopher M; Lauzon, Julie; Ibrahim, Ahmed Ibrahim Elsayed; Nava, Caroline; Héron, Delphine; van Aalst, Minke M A; Atemin, Slavena; Sleptsova, Mila; Aleksandrova, Iliyana; Todorova, Albena; Watkins, Debra L; Kozenko, Mariya A; Natera-de Benito, Daniel; Ortez, Carlos; Estevez-Arias, Berta; Lecoquierre, François; Cassinari, Kévin; Guerrot, Anne-Marie; Levy, Jonathan; Latypova, Xenia; Verloes, Alain; Innes, A Micheil; Yang, Xiao-Ru; Banka, Siddharth; Vill, Katharina; Jacob, Maureen; Kruer, Michael; Skidmore, Peter; Galaz-Montoya, Carolina I; Bakhtiari, Somayeh; Mester, Jessica L; Granato, Michael; Armache, Karim-Jean; Costain, Gregory; Korb, Erica

Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling.

组蛋白变体H2BE控制活性依赖性基因表达和稳态调节。

Feierman Emily R, Paranjapye Alekh, Sangree Annabel K, Ahmad Rili, Maroni Marissa J, Qiu Qi, Choi Kyuhyun, Fuccillo Marc, Wu Hao, Korb Erica

Exposure to a low dose mixture of endocrine disrupting chemicals alters the brain transcriptome and animal behavior

暴露于低剂量内分泌干扰化学物质混合物会改变大脑转录组和动物行为。

Paranjapye, Alekh; Ahmad, Rili; Quaye, Camille N; Rico, Andre L G; Palmiero, Nicole; Simons, Rebecca A; Lien, Yu-Chin; Hall, Molly; Korb, Erica

Autism spectrum disorder risk genes have convergent effects on transcription and neuronal firing patterns in primary neurons.

自闭症谱系障碍风险基因对初级神经元的转录和神经元放电模式具有趋同效应

Paranjapye Alekh, Ahmad RIli, Su Steven, Waldman Abraham J, Philips-Cremins Jennifer, Zhang Shuo, Korb Erica

Transcriptomic Profiling of Extracellular RNAs Present in Cerebrospinal Fluid Identifies Differentially Expressed Transcripts in Parkinson's Disease

脑脊液中细胞外RNA的转录组分析鉴定出帕金森病中差异表达的转录本

Hossein-Nezhad, Arash; Fatemi, Roya Pedram; Ahmad, Rili; Peskind, Elaine R; Zabetian, Cyrus P; Hu, Shu-Ching; Shi, Min; Wahlestedt, Claes; Zhang, Jing; Faghihi, Mohammad Ali

Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1

稳定的半胱氨酸亚磺酸的形成对于帕金森病蛋白DJ-1的线粒体功能至关重要。

Blackinton, Jeff; Lakshminarasimhan, Mahadevan; Thomas, Kelly J; Ahmad, Rili; Greggio, Elisa; Raza, Ashraf S; Cookson, Mark R; Wilson, Mark A

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

与隐性帕金森病相关的PTEN诱导的假定激酶1的突变对蛋白质稳定性有不同的影响。

Beilina, Alexandra; Van Der Brug, Marcel; Ahmad, Rili; Kesavapany, Sashi; Miller, David W; Petsko, Gregory A; Cookson, Mark R

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

帕金森病蛋白DJ-1具有神经保护作用,这是由于半胱氨酸亚磺酸驱动的线粒体定位所致。

Canet-Avilés, Rosa M; Wilson, Mark A; Miller, David W; Ahmad, Rili; McLendon, Chris; Bandyopadhyay, Sourav; Baptista, Melisa J; Ringe, Dagmar; Petsko, Gregory A; Cookson, Mark R