A multicenter, randomized, and double-blind phase IV clinical trial to compare the efficacy and safety of fixed-dose combinations of amlodipine orotate/valsartan 5/160 mg versus valsartan/hydrochlorothiazide 160/12.5 mg in patients with essential hypertension uncontrolled by valsartan 160 mg monotherapy
一项多中心、随机、双盲IV期临床试验,旨在比较氨氯地平乳清酸盐/缬沙坦5/160 mg固定剂量复方制剂与缬沙坦/氢氯噻嗪160/12.5 mg复方制剂在缬沙坦160 mg单药治疗控制不佳的原发性高血压患者中的疗效和安全性。
期刊:Medicine
影响因子:1.4
doi:10.1097/MD.0000000000012329
Ahn, Youngkeun; Kim, Yongcheol; Chang, Kiyuk; Kim, Weon; Rhee, Moo-Yong; Cha, Kwang Soo; Hyon, Min Su; Shim, Chi Young; Lee, Sung Yun; Kim, Doo Il; Kim, Sang Wook; Lim, Sang-Wook; Han, Kyoo-Rok; Jo, Sang-Ho; Lee, Nae-Hee; Kwan, Jun; Ahn, Taehoon