The PARP-1 inhibitor Olaparib suppresses BRCA1 protein levels, increases apoptosis and causes radiation hypersensitivity in BRCA1(+/-) lymphoblastoid cells

PARP-1抑制剂奥拉帕尼可抑制BRCA1蛋白水平，增加细胞凋亡，并导致BRCA1(+/-)淋巴母细胞对辐射过敏。