The PKCι-β-arrestin2 axis disrupts SORLA retrograde trafficking, driving its degradation and amyloid pathology in Alzheimer's disease.
PKCα-β-arrestin2 轴会破坏 SORLA 的逆向运输，从而导致其降解和阿尔茨海默病中的淀粉样蛋白病理
期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-025-00865-6
Rehman Hasibur, Yan Shun, Saggu Shalini, Aida Mae, Zhang Fang, Shu Yang, Jones Alexis, Trang Amy, Dew Emily, Zhi Wenbo, Claeboe Emily T, Baucum Anthony J 2nd, Wu Guangyu, Jiao Kai, Wang Qin
