日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Deciphering the role of cDC2s in Sjögren's syndrome: transcriptomic profile links altered antigen processes with IFN signature and autoimmunity

揭示 cDC2 在干燥综合征中的作用：转录组谱将改变的抗原过程与 IFN 特征和自身免疫联系起来

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/ard-2022-222728
Lopes, Ana P; Hillen, Maarten R; Hinrichs, Anneline C; Blokland, Sofie Lm; Bekker, Cornelis Pj; Pandit, Aridaman; Kruize, Aike A; Radstake, Timothy Rdj; van Roon, Joel A
干燥综合征
免疫/内分泌
发表日期：2023
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CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells

原发性干燥综合征中CCR9/CXCR5共表达的CD4 T细胞增多，且富含PD-1/ICOS表达的效应T细胞。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241511952
Hinrichs, Anneline C; Kruize, Aike A; Lafeber, Floris P J G; Leavis, Helen L; van Roon, Joel A G
干燥综合征
T细胞
ICOS
PD-1
T细胞
细胞生物学
CD4
免疫/内分泌
发表日期：2023
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Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren's syndrome that show potential to predict and monitor clinical response

来氟米特/羟氯喹联合疗法靶向干燥综合征患者体内I型干扰素相关蛋白，有望用于预测和监测临床疗效

期刊:RMD Open
影响因子:4.7
doi:10.1136/rmdopen-2023-002979
Hamkour, Safae; van der Heijden, Eefje Hm; Lopes, Ana P; Blokland, Sofie L M; Bekker, Cornelis P J; Van Helden-Meeuwsen, Cornelia G; Versnel, Marjan A; Kruize, Aike A; Radstake, Timothy Rdj; Leavis, Helen L; Hillen, Maarten R; van Roon, Joel Ag
干燥综合征
免疫/内分泌
发表日期：2023
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In patients with primary Sjögren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells

在原发性干燥综合征患者中，固有样MAIT细胞表现出IL-7R、IFN-γ和IL-21表达上调，并且CCR9和CXCR5表达细胞的比例增加。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2022.1017157
Hinrichs, Anneline C; Kruize, Aike A; Leavis, Helen L; van Roon, Joel A G
IL-21
干燥综合征
T细胞
IL-7
T细胞
IFN-γ
IL-2
细胞生物学
免疫/内分泌
发表日期：2022
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CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren's Syndrome

CCR9+ CD8 T 细胞释放 CCL5：原发性干燥综合征免疫病理的潜在因素

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2022.887972
Hinrichs, Anneline C; Blokland, Sofie L M; Kruize, Aike A; Lafeber, Floris P J; Leavis, Helen L; van Roon, Joel A G
干燥综合征
T细胞
CCL5
CD8
细胞生物学
免疫/内分泌
发表日期：2022
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Transcriptome Analysis of CCR9+ T Helper Cells From Primary Sjögren's Syndrome Patients Identifies CCL5 as a Novel Effector Molecule

对原发性干燥综合征患者CCR9+ T辅助细胞的转录组分析发现CCL5是一种新的效应分子

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2021.702733
Hinrichs, Anneline C; Blokland, Sofie L M; Lopes, Ana P; Wichers, Catharina G K; Kruize, Aike A; Pandit, Aridaman; Radstake, Timothy R D J; van Roon, Joel A G
细胞生物学
CCL5
干燥综合征
免疫/内分泌
发表日期：2021
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The Transcriptomic Profile of Monocytes from Patients With Sjögren's Syndrome Is Associated With Inflammatory Parameters and Is Mimicked by Circulating Mediators

干燥综合征患者单核细胞的转录组谱与炎症参数相关，并被循环介质模仿

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2021.701656
Ana P Lopes, Cornelis P J Bekker, Maarten R Hillen, Sofie L M Blokland, Anneline C Hinrichs, Aridaman Pandit, Aike A Kruize, Timothy R D J Radstake, Joel A G van Roon
免疫
细胞生物学
单核细胞
发表日期：2021
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Epigenetically quantified immune cells in salivary glands of Sjögren's syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology

利用表观遗传学方法定量分析干燥综合征患者唾液腺中的免疫细胞：一种检测滤泡辅助性T细胞与免疫病理学之间强相关性的新工具

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/kez268
Blokland, Sofie L M; van Vliet-Moret, Fréderique M; Hillen, Maarten R; Pandit, Aridaman; Goldschmeding, Roel; Kruize, Aike A; Bouma, Gerben; van Maurik, André; Olek, Sven; Hoffmueller, Ulrich; van Roon, Joel A G; Radstake, Timothy R D J
表观遗传
干燥综合征
T细胞
T细胞
细胞生物学
免疫/内分泌
发表日期：2020
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Decreased circulating CXCR3 + CCR9+T helper cells are associated with elevated levels of their ligands CXCL10 and CCL25 in the salivary gland of patients with Sjögren's syndrome to facilitate their concerted migration

干燥综合征患者唾液腺中循环CXCR3+CCR9+辅助性T细胞数量减少，同时其配体CXCL10和CCL25水平升高，从而促进这些细胞的协同迁移。

期刊:Scandinavian Journal of Immunology
影响因子:1.6
doi:10.1111/sji.12852
Blokland, Sofie L M; Kislat, Andreas; Homey, Bernhard; Smithson, Glennda M; Kruize, Aike A; Radstake, Timothy R D J; van Roon, Joel A G
干燥综合征
T细胞
CCL2
CCL25
CXCL1
CXCR3
CXCL10
T细胞
细胞生物学
免疫/内分泌
发表日期：2020
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Plasmacytoid DCs From Patients With Sjögren's Syndrome Are Transcriptionally Primed for Enhanced Pro-inflammatory Cytokine Production

来自干燥综合征患者的浆细胞样树突状细胞在转录水平上已被激活，从而增强促炎细胞因子的产生。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2019.02096
Hillen, Maarten R; Pandit, Aridaman; Blokland, Sofie L M; Hartgring, Sarita A Y; Bekker, Cornelis P J; van der Heijden, Eefje H M; Servaas, Nila H; Rossato, Marzia; Kruize, Aike A; van Roon, Joel A G; Radstake, Timothy R D J
干燥综合征
树突状细胞
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2019
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