日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The host protein cyclophilin A restricts nuclear entry of HIV-1 mutants by reducing the elasticity of the viral capsid

宿主蛋白环孢亲和素A通过降低病毒衣壳的弹性来限制HIV-1突变体进入细胞核。

Hong, Jun; Deshpande, Akshay; Thakare, Yatish; Simonovsky, Lora; Douglas, AidanDarian W; Guinness, Conall Mc; Rotem-Dai, Noa; Kortyna, Michelle L; Klarhof, J Ole; Shi, Jiong; James, Leo C; Boecking, Till; Francis, Ashwanth C; Rousso, Itay; Aiken, Christopher

HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability.

HIV-1 核输入具有选择性,取决于衣壳弹性和核孔适应性

Hou Zhen, Shen Yao, Fronik Stanley, Shen Juan, Shi Jiong, Xu Jialu, Chen Long, Hardenbrook Nathan, Engelman Alan N, Aiken Christopher, Zhang Peijun

Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat

Lenacapavir 在未成熟 HIV-1 中的独特靶位点及其与成熟抑制剂 Bevirimat 的协同结合

Wu, Chunxiang; Meuser, Megan E; Rey, Juan S; Meshkin, Hamed; Yang, Rachel; Devarkar, Swapnil C; Freniere, Christian; Shi, Jiong; Aiken, Christopher; Perilla, Juan R; Xiong, Yong

HIV-1 binds dynein directly to hijack microtubule transport machinery.

HIV-1 直接与动力蛋白结合,劫持微管运输机制

Badieyan Somayesadat, Lichon Drew, Keceli Sevnur Komurlu, Andreas Michael P, Gillies John P, Peng Wang, Shi Jiong, DeSantis Morgan E, Aiken Christopher R, Böcking Till, Giessen Tobias W, Campbell Edward M, Cianfrocco Michael A

CPSF6 promotes HIV-1 preintegration complex function.

CPSF6促进HIV-1整合前复合物的功能

Chaudhuri Evan, Jang Sooin, Chakraborty Rajasree, Radhakrishnan Rajalingam, Arnarson Bjarki, Prakash Prem, Cornish Daphne, Rohlfes Nicholas, Singh Parmit K, Shi Jiong, Aiken Christopher, Campbell Edward, Hultquist Judd, Balsubramaniam Muthukumar, Engelman Alan N, Dash Chandravanu

The host protein cyclophilin A inhibits HIV-1 nuclear entry by decreasing capsid elasticity

宿主蛋白亲环蛋白A通过降低衣壳弹性来抑制HIV-1进入细胞核。

Hong, Jun; Deshpande, Akshay; Thakare, Yatish; Simonovsky, Lora; Douglas, AidanDarian W; Mc Guinness, Conall; Rotem-Dai, Noa; Kortyna, Michelle L; Klarhof, J Ole; Shi, Jiong; Boecking, Till; James, Leo C; Francis, Ashwanth C; Rousso, Itay; Aiken, Christopher

Reverse transcription progression and genome length regulate HIV-1 core elasticity and disassembly

逆转录进程和基因组长度调控HIV-1核心的弹性和解体

Deshpande, Akshay; Shi, Jiong; Rotem-Dai, Noa; Aiken, Christopher; Rousso, Itay

Correlative In Situ Cryo-ET Reveals Cellular and Viral Remodeling Associated with Selective HIV-1 Core Nuclear Import.

相关原位冷冻电镜断层扫描揭示了与 HIV-1 核心选择性核输入相关的细胞和病毒重塑

Hou Zhen, Shen Yao, Fronik Stanley, Shen Juan, Shi Jiong, Xu Jialu, Chen Long, Hardenbrook Nathan, Thompson Christopher, Neumann Sarah, Engelman Alan N, Aiken Christopher, Zhang Peijun

Elasticity of the HIV-1 core facilitates nuclear entry and infection

HIV-1核心的弹性有利于病毒进入细胞核并引发感染。

Deshpande, Akshay; Bryer, Alexander J; Andino-Moncada, Jonathan R; Shi, Jiong; Hong, Jun; Torres, Cameron; Harel, Shimon; Francis, Ashwanth C; Perilla, Juan R; Aiken, Christopher; Rousso, Itay

Oceanographical-driven dispersal and environmental variation explain genetic structure in an upwelling coastal ecosystem

海洋驱动的扩散和环境变化解释了上升流沿岸生态系统的遗传结构

Peluso, Lívia; Faúndez, Juan; Navarrete, Sergio A; Broitman, Bernardo R; Aiken, Christopher M; Saenz-Agudelo, Pablo