Aimee L Edinger相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Sphingosine simultaneously inhibits nuclear import and activates PP2A by binding importins and PPP2R1A

鞘氨醇通过与输入蛋白和PPP2R1A结合，同时抑制核输入并激活PP2A。

期刊:EMBO Journal

影响因子:9.4

doi:10.1038/s44318-025-00490-5

Vaishali Jayashankar # ,Peter Kubiniok # ,Alison N McCracken # ,Rebeca G Gentry ,Kazumi H Eckenstein ,Lorenzo Sernissi ,Vito Vece ,Jean-Baptiste Garsi ,Sarah Y Valles ,Sunhee Jung ,Natalie C Hoffman ,Arielle S Perrochon ,Elizabeth M Selwan ,Brendan T Finicle ,Mary Pitman ,DaWei Lin ,Éric Bonneil ,Ruijuan Xu ,Cungui Mao ,Peter Kaiser ,David A Fruman ,David Mobley ,Cholsoon Jang ,Stephen Hanessian ,Pierre Thibault ,Aimee L Edinger

发表日期：2025

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CARMIL1-AA selectively inhibits macropinocytosis while sparing autophagy

CARMIL1-AA选择性抑制巨胞饮作用，同时不影响自噬作用

期刊:Molecular Biology of the Cell

影响因子:3.1

doi:10.1091/mbc.E24-09-0434

Rebecca M Lim ，Alexa Lu ，Brennan M Chuang ，Cecily Anaraki ，Brandon Chu ，Christopher J Halbrook ，Aimee L Edinger

发表日期：2025

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Circulating biomarkers of kidney angiomyolipoma and cysts in tuberous sclerosis complex patients

结节性硬化症患者肾血管平滑肌脂肪瘤和囊肿的循环生物标志物

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2024.110265

Varvara I Rubtsova, Yujin Chun, Joohwan Kim, Cuauhtemoc B Ramirez, Sunhee Jung, Wonsuk Choi, Miranda E Kelly, Miranda L Lopez, Elizabeth Cassidy, Gabrielle Rushing, Dean J Aguiar, Wei Ling Lau, Rebecca S Ahdoot, Moyra Smith, Aimee L Edinger, Sang-Guk Lee, Cholsoon Jang, Gina Lee

多发性硬化症

发表日期：2024

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Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics

同时抑制内吞循环和溶酶体融合使细胞和组织对寡核苷酸疗法敏感

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkad023

Brendan T Finicle, Kazumi H Eckenstein, Alexey S Revenko, Brooke A Anderson, W Brad Wan, Alison N McCracken, Daniel Gil, David A Fruman, Stephen Hanessian, Punit P Seth, Aimee L Edinger

细胞生物学

发表日期：2023

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Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy

依赖 Rab7 的内体和自噬加工最终共同途径的破坏导致严重的足细胞病

期刊:Journal of the American Society of Nephrology

影响因子:10.3

doi:10.1681/ASN.0000000000000126

Kristin Vöing, Ulf Michgehl, Nils David Mertens, Cara Picciotto, Mee-Ling Maywald, Jonas Goretzko, Sofie Waimann, Kevin Gilhaus, Manuel Rogg, Christoph Schell, Jürgen Klingauf, Yaroslav Tsytsyura, Uwe Hansen, Veerle van Marck, Aimee L Edinger, Beate Vollenbröker, Ursula Rescher, Daniela Anne Braun,

细胞生物学

发表日期：2023

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Rab7a activation promotes degradation of select tight junction proteins at the blood-brain barrier after ischemic stroke

缺血性中风后，Rab7a 激活会促进血脑屏障上某些紧密连接蛋白的降解

doi:10.1101/2023.08.29.555373

Azzurra Cottarelli, Sanjid Shahriar, Ahmet Arac, Michael Glendinning, Mary Claire Tuohy, Grace Prochilo, Jason B Neal, Aimee L Edinger, Dritan Agalliu

发表日期：2023

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Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity

类药物鞘脂 SH-BC-893 可抵抗神经酰胺诱导的线粒体裂变并纠正饮食引起的肥胖

期刊:EMBO Molecular Medicine

doi:10.15252/emmm.202013086

Vaishali Jayashankar, Elizabeth Selwan, Sarah E Hancock, Amandine Verlande, Maggie O Goodson, Kazumi H Eckenstein, Giedre Milinkeviciute, Brianna M Hoover, Bin Chen, Angela G Fleischman, Karina S Cramer, Stephen Hanessian, Selma Masri, Nigel Turner, Aimee L Edinger

发表日期：2021

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Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs

动态磷酸化蛋白质组学揭示抗癌鞘脂类似物调控的信号通路

期刊:Molecular & Cellular Proteomics

影响因子:6.1

doi:10.1074/mcp.RA118.001053

Peter Kubiniok ，Brendan T Finicle ，Fanny Piffaretti ，Alison N McCracken ，Michael Perryman ，Stephen Hanessian ，Aimee L Edinger ，Pierre Thibault

发表日期：2019

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In search of constrained FTY720 and phytosphingosine analogs as dual acting anticancer agents targeting metabolic and epigenetic pathways

寻找受限的 FTY720 和植物鞘氨醇类似物作为针对代谢和表观遗传途径的双重作用抗癌剂

期刊:European Journal of Medicinal Chemistry

doi:10.1016/j.ejmech.2018.09.043

Jean-Baptiste Garsi, Lorenzo Sernissi, Vito Vece, Stephen Hanessian, Alison N McCracken, Grigor Simitian, Aimee L Edinger

发表日期：2018

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Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6

鞘脂通过使ARF6失活来抑制营养转运蛋白的内体循环。

期刊:Journal of Cell Science

影响因子:3.3

doi:10.1242/jcs.213314

Brendan T Finicle ，Manuel U Ramirez ，Gang Liu ，Elizabeth M Selwan ，Alison N McCracken ，Jingwen Yu ，Yoosun Joo ，Jannett Nguyen ，Kevin Ou ，Saurabh Ghosh Roy ，Victor D Mendoza ，Dania Virginia Corrales ，Aimee L Edinger

发表日期：2018

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