日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy

对人类短尾蛋白DNA识别的结构性见解以及用于癌症治疗的新型结合剂的发现

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-56213-1
Newman, Joseph A; Gavard, Angeline E; Imprachim, Nergis; Aitkenhead, Hazel; Sheppard, Hadley E; Te Poele, Robert; Clarke, Paul A; Hossain, Mohammad Anwar; Temme, Louisa; Oh, Hans J; Wells, Carrow I; Davis-Gilbert, Zachary W; Workman, Paul; Gileadi, Opher; Drewry, David H
肿瘤
肿瘤免疫
发表日期：2025
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Gluebodies Offer a Route To Improve Crystal Reliability and Diversity through Transferable Nanobody Mutations That Introduce Constitutive Close Contacts

胶体提供了一种通过可转移的纳米抗体突变来提高晶体可靠性和多样性的途径，这些突变引入了组成性的紧密接触。

期刊:ACS Central Science
影响因子:10.4
doi:10.1021/acscentsci.5c00937
Ye, Mingda; Makola, Mpho; Richards, Mark W; Newman, Joseph A; Fairhead, Michael; Burgess, Selena G; Wu, Zhihuang; Maclean, Elizabeth; Wright, Nathan D; Koekemoer, Lizbé; Thompson, Andrew; Bezerra, Gustavo Arruda; Yi, Gangshun; Li, Huanyu; Rangel, Victor L; Mamalis, Dimitrios; Aitkenhead, Hazel; Davis, Benjamin G; Gilbert, Robert J C; Duerr, Katharina L; Bayliss, Richard; Gileadi, Opher; von Delft, Frank
发表日期：2025
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Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair

金属蛋白酶SPRTN/DVC1调控复制偶联的DNA-蛋白质交联修复

期刊:Molecular Cell
影响因子:16.6
doi:10.1016/j.molcel.2016.09.032
Vaz, Bruno; Popovic, Marta; Newman, Joseph A; Fielden, John; Aitkenhead, Hazel; Halder, Swagata; Singh, Abhay Narayan; Vendrell, Iolanda; Fischer, Roman; Torrecilla, Ignacio; Drobnitzky, Neele; Freire, Raimundo; Amor, David J; Lockhart, Paul J; Kessler, Benedikt M; McKenna, Gillies W; Gileadi, Opher; Ramadan, Kristijan
信号转导
发表日期：2016
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Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway

DNA聚合酶θ的解旋酶结构域的结构揭示了其在微同源介导的末端连接途径中可能发挥的作用

期刊:Structure
影响因子:4.3
doi:10.1016/j.str.2015.10.014
Newman, Joseph A; Cooper, Christopher D O; Aitkenhead, Hazel; Gileadi, Opher
发表日期：2015
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Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: DETERMINANTS OF DNA BINDING AND REDOX REGULATION BY DISULFIDE BOND FORMATION.

转录因子 Etv1、Etv4、Etv5 和 Fev 的 Ets 蛋白 DNA 结合域的结构：二硫键形成决定 DNA 结合和氧化还原调控

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M115.646737
Cooper Christopher D O, Newman Joseph A, Aitkenhead Hazel, Allerston Charles K, Gileadi Opher
免疫/内分泌
发表日期：2015
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