日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Glioblastoma cells that evade chemoradiotherapy-induced cell death exhibit a bifurcated glycolytic program

能够逃避化疗和放疗诱导的细胞死亡的胶质母细胞瘤细胞表现出一种分叉的糖酵解程序。

Martell, Emma; Kuzmychova, Helgi; Chawla, Ujala; Grewal, Akaljot; Jain, Charul; Venugopal, Chitra; Anderson, Christopher M; Singh, Sheila K; Sharif, Tanveer

Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature

协调分化人类肠道类器官,使其具有功能性肠神经元和血管系统

Charlie J Childs ,Holly M Poling ,Kevin Chen ,Yu-Hwai Tsai ,Angeline Wu ,Abigail Vallie ,Madeline K Eiken ,Sha Huang ,Caden W Sweet ,Ryan Schreiner ,Zhiwei Xiao ,Ryan C Spencer ,Samantha A Paris ,Ansley S Conchola ,Jonathan W Villanueva ,Meghan F Anderman ,Emily M Holloway ,Akaljot Singh ,Roman J Giger ,Maxime M Mahe ,Claudia Loebel ,Michael A Helmrath ,Katherine D Walton ,Shahin Rafii ,Jason R Spence

Disease stage-specific role of the mitochondrial pyruvate carrier suppresses differentiation in temozolomide and radiation-treated glioblastoma

线粒体丙酮酸载体在疾病阶段特异性作用下抑制替莫唑胺和放射治疗的胶质母细胞瘤的分化

Martell, Emma; Kuzmychova, Helgi; Senthil, Harshal; Chawla, Ujala; Kaul, Esha; Grewal, Akaljot; Banerji, Versha; Anderson, Christopher M; Venugopal, Chitra; Miller, Donald; Werbowetski-Ogilvie, Tamra E; Singh, Sheila K; Sharif, Tanveer

Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells

从多能干细胞中衍生出具有功能性组织驻留巨噬细胞的人类肠道类器官

Kentaro Tominaga, Daniel O Kechele, J Guillermo Sanchez, Simon Vales, Ingrid Jurickova, Lizza Roman, Akihiro Asai, Jacob R Enriquez, Heather A McCauley, Keishi Kishimoto, Kentaro Iwasawa, Akaljot Singh, Yuko Horio, Jorge O Múnera, Takanori Takebe, Aaron M Zorn, Michael A Helmrath, Lee A Denson, Jame

Thermal Annealing Enhances Piezoelectricity and Regenerative Potential of PVDF-TrFE Nanofiber Scaffolds

热退火增强PVDF-TrFE纳米纤维支架的压电性和再生潜力

Krutko, Maksym; Poling, Holly M; Sheth, Maulee; Kongsomros, Supasek; Bryan, Andrew E; Sharma, Manju; Singh, Akaljot; Reza, Hasan A; Wikenheiser-Brokamp, Kathryn A; Takebe, Takanori; Helmrath, Michael A; Harris, Greg M; Esfandiari, Leyla

Engineering Large-Scale and Innervated Functional Human Gut for Transplantation

构建用于移植的大规模、神经支配的功能性人类肠道

Poling, Holly M; Noël, Théo; Singh, Akaljot; Fisher, Garrett W; Thorner, Konrad; Chaturvedi, Praneet; Nattamai, Kalpana; Srivastava, Kalpana; Batie, Matthew R; Hausfeld, Taylor; Pitstick, Amy L; Ménoret, Séverine; Anegon, Ignacio; Barrile, Riccardo; Mayhew, Christopher N; Takebe, Takanori; Wells, James M; Helmrath, Michael A; Mahe, Maxime M

Human pluripotent stem cell-derived organoids repair damaged bowel in vivo

人类多能干细胞衍生的类器官可在体内修复受损肠道

Holly M Poling ,Nambirajan Sundaram ,Garrett W Fisher ,Akaljot Singh ,Joseph R Shiley ,Kalpana Nattamai ,Vinothini Govindarajah ,Alexander R Cortez ,Maksym O Krutko ,Séverine Ménoret ,Ignacio Anegon ,Magdalena Kasendra ,James M Wells ,Christopher N Mayhew ,Takanori Takebe ,Maxime M Mahe ,Michael A Helmrath

WNT2B Deficiency Causes Enhanced Susceptibility to Colitis Due to Increased Inflammatory Cytokine Production

WNT2B 缺乏导致炎症细胞因子产生增加,从而增加患结肠炎的易感性

Amy E O'Connell, Sathuwarman Raveenthiraraj, Luiz Fernando Silva Oliveira, Comfort Adegboye, Venkata Siva Dasuri, Wanshu Qi, Radhika S Khetani, Akaljot Singh, Nambirajam Sundaram, Jasmine Lin, Prathima Nandivada, Lorena Rincón-Cruz, Jeffrey D Goldsmith, Jay R Thiagarajah, Diana L Carlone, Jerrold R

Specific binding sites on Rhesus rotavirus capsid protein dictate the method of endocytosis inducing the murine model of biliary atresia

恒河猴轮状病毒衣壳蛋白上的特定结合位点决定了诱导胆道闭锁小鼠模型的内吞方法

Haley Temple, Bryan Donnelly, Sujit K Mohanty, Sarah Mowery, Holly M Poling, Rajamouli Pasula, Stephen Hartman, Akaljot Singh, Reena Mourya, Alexander Bondoc, Jaroslaw Meller, Anil G Jegga, Kei Oyama, Monica McNeal, Paul Spearman, Greg Tiao

Transplanted human intestinal organoids: a resource for modeling human intestinal development

移植的人类肠道类器官:模拟人类肠道发育的资源

Akaljot Singh, Holly M Poling, Praneet Chaturvedi, Konrad Thorner, Nambirajan Sundaram, Daniel O Kechele, Charlie J Childs, Heather A McCauley, Garrett W Fisher, Nicole E Brown, Jason R Spence, James M Wells, Michael A Helmrath