The angiotensin receptor blocker, losartan, reduces inflammation and fibrosis, and prevents relapse of fibrosis after steroid-induced remission, in mice prone to Crohn's disease-like ileitis.
血管紧张素受体阻滞剂氯沙坦可减轻炎症和纤维化，并防止易患克罗恩病样回肠炎的小鼠在类固醇诱导缓解后纤维化复发
期刊:Journal of Crohns & Colitis
影响因子:8.7
doi:10.1093/ecco-jcc/jjaf083
Artone Serena, Ray Shuvra, Williams Joseph J, Akbulut Kenan, Cordero Paul, Gómez-Ãriz Ana M, Friedman Hannah R, Saline Anna V, Hart Isabel M, Vadivelan Elakia, Parigi Tommaso L, Pietropaoli Davide, Latella Giovanni, Sanderson Jeremy D, De Salvo Carlo, Oben Jude A, Pizarro Theresa T, De Santis Stefania
