日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatiotemporal architecture of immune cells and cancer-associated fibroblasts in high-grade serous ovarian carcinoma

高级别浆液性卵巢癌中免疫细胞和癌症相关成纤维细胞的时空结构

Alexander M Xu, Marcela Haro, Ann E Walts, Ye Hu, Joshi John, Beth Y Karlan, Akil Merchant, Sandra Orsulic

Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors

先天性和适应性免疫细胞相互作用驱动炎症小体激活和肝细胞凋亡,从而导致免疫检查点抑制剂引起的鼠肝损伤。

Layla Shojaie # ,Jacob M Bogdanov # ,Helia Alavifard ,Mahmoud G Mohamed ,Aria Baktash ,Myra Ali ,Simeon Mahov ,Sue Murray ,Gary C Kanel ,Zhang-Xu Liu ,Fumito Ito ,Gino K In ,Akil Merchant ,William Stohl ,Lily Dara

HIV infection and ART exposure affect tumor TCR repertoire of diffuse large B cell lymphoma

HIV 感染和 ART 暴露影响弥漫大 B 细胞淋巴瘤的肿瘤 TCR 库

Sophia M Roush, Jenny Coelho, Alexander M Xu, Kaushik Puranam, Marriam Mponda, Edwards Kasonkanji, Maurice Mulenga, Tamiwe Tomoka, Jonathan Galeotti, Amy Brownlee, Hormas Ghadially, Maganizo Chagomerana, Blossom Damania, Matthew Painschab, Akil Merchant, Satish Gopal, Yuri Fedoriw

Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment

脂肪肝中的细胞外囊泡促进转移性肿瘤微环境的形成

Zhijun Wang ,So Yeon Kim ,Wei Tu ,Jieun Kim ,Alexander Xu ,Yoon Mee Yang ,Michitaka Matsuda ,Lien Reolizo ,Takashi Tsuchiya ,Sandrine Billet ,Alexandra Gangi ,Mazen Noureddin ,Ben A Falk ,Sungjin Kim ,Wei Fan ,Mourad Tighiouart ,Sungyong You ,Michael S Lewis ,Stephen J Pandol ,Dolores Di Vizio ,Akil Merchant ,Edwin M Posadas ,Neil A Bhowmick ,Shelly C Lu ,Ekihiro Seki

Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial

全面的单细胞免疫分析确定了 Ib 期试验中溶瘤病毒治疗后患者的多发性骨髓瘤微环境

Steffan T Nawrocki #, Julian Olea #, Claudia Villa Celi, Homa Dadrastoussi, Kaijin Wu, Denice Tsao-Wei, Anthony Colombo, Matt Coffey, Eduardo Fernandez Hernandez, Xuelian Chen, Gerard J Nuovo, Jennifer S Carew, Ann F Mohrbacher, Paul Fields, Peter Kuhn, Imran Siddiqi, Akil Merchant, Kevin R Kelly

Evidence of premature lymphocyte aging in people with low anti-spike antibody levels after BNT162b2 vaccination

BNT162b2疫苗接种后,抗刺突蛋白抗体水平低的人群中存在淋巴细胞过早衰老的证据。

Yapei Huang ,Juliana E Shin ,Alexander M Xu ,Changfu Yao ,Sandy Joung ,Min Wu ,Ruan Zhang ,Bongha Shin ,Joslyn Foley ,Simeon B Mahov ,Matthew E Modes ,Joseph E Ebinger ,Matthew Driver ,Jonathan G Braun ,Caroline A Jefferies ,Tanyalak Parimon ,Chelsea Hayes ,Kimia Sobhani ,Akil Merchant ,Sina A Gharib ,Stanley C Jordan ,Susan Cheng ,Helen S Goodridge ,Peter Chen

Enrichment-Free Single-Cell Detection and Morphogenomic Profiling of Myeloma Patient Samples to Delineate Circulating Rare Plasma Cell Clones

对骨髓瘤患者样本进行非富集单细胞检测和形态基因组学分析,以描绘循环中稀有的浆细胞克隆

Libere J Ndacayisaba, Kate E Rappard, Stephanie N Shishido, Carmen Ruiz Velasco, Nicholas Matsumoto, Rafael Navarez, Guilin Tang, Pei Lin, Sonia M Setayesh, Amin Naghdloo, Ching-Ju Hsu, Carlisle Maney, David Symer, Kelly Bethel, Kevin Kelly, Akil Merchant, Robert Orlowski, James Hicks, Jeremy Mason,

Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells

牙周炎症通过增加髓系抑制细胞来招募远处转移性乳腺癌细胞

Ran Cheng #, Sandrine Billet #, Chuanxia Liu, Subhash Haldar, Diptiman Choudhury, Manisha Tripathi, Monirath Hav, Akil Merchant, Tao Hu, Haiyun Huang, Hongmei Zhou, Neil A Bhowmick

Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera

血小板生成素是真性红细胞增多症 JAK2V617F 转基因小鼠模型中完全表型表达所必需的

Jerry L Spivak, Akil Merchant, Donna M Williams, Ophelia Rogers, Wanke Zhao, Amy Duffield, Linda S Resar, Alison R Moliterno, Zhizhuang J Zhao

Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors

Gli1 调节 HSC 和髓系祖细胞的增殖和分化

Akil Merchant, Giselle Joseph, Qiuju Wang, Sarah Brennan, William Matsui