日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Design and Synthesis of 4-Arylazo Pyrazole Carboxamides as Dual AChE/BChE Inhibitors: Kinetic and In Silico Evaluation

4-芳基偶氮吡唑甲酰胺类化合物作为双重AChE/BChE抑制剂的设计与合成：动力学和计算机模拟评价

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph19020239
Akocak, Suleyman; Lolak, Nebih; Duran, Hatice Esra; Demir Çetinkaya, Büşra; Hashem, Hamada; Bräse, Stefan; Türkeş, Cüneyt
发表日期：2026
文献求助 收藏

Isovanillin-derived bis-hydrazones as dual cholinesterase and carbonic anhydrase inhibitors: synthesis, enzymatic profiling, and computational insights from molecular docking and dynamics

异香草醛衍生的双腙作为胆碱酯酶和碳酸酐酶双重抑制剂：合成、酶学分析以及分子对接和动力学计算见解

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2026.2617608
Türkeş, Cüneyt; Yapar, Gönül; Duran, Hatice Esra; Lolak, Nebih; Akocak, Suleyman
发表日期：2026
文献求助 收藏

From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents

从感染到肿瘤：探索环丙沙星衍生物作为抗癌药物的治疗潜力

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph18010072
Hassan, Hesham M; Hassan, Roket; Elmagzoub, Ranya Mohammed; Al-Emam, Ahmed; Kossenas, Konstantinos; Abdel-Samea, Ahmed S; Khalifa, Hazim O; Akocak, Suleyman; Bräse, Stefan; Hashem, Hamada
炎症/感染
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Investigating the Anti-Inflammatory Potential of SLC-0111: A Carbonic Anhydrase Inhibitor Targeting Cyclooxygenase-Mediated Inflammatory Pathways in a Carrageenan-Induced Rat Model

研究SLC-0111的抗炎潜力：一种靶向环氧合酶介导的炎症通路的碳酸酐酶抑制剂，以角叉菜胶诱导的大鼠模型为模型

期刊:Journal of Biochemical and Molecular Toxicology
影响因子:2.8
doi:10.1002/jbt.70217
Doğan, Aslınur; Yanılmaz, Elif Merve Betül; Karakoc, Gulcin; Parlar, Ali; Annaç, Ebru; Lolak, Nebih; Akocak, Suleyman
信号转导
炎症/感染
Rat
炎症
发表日期：2025
文献求助 收藏

Sulfonamide-Bearing Pyrazolone Derivatives as Multitarget Therapeutic Agents: Design, Synthesis, Characterization, Biological Evaluation, In Silico ADME/T Profiling and Molecular Docking Study

磺酰胺基吡唑酮衍生物作为多靶点治疗剂：设计、合成、表征、生物学评价、计算机模拟ADME/T分析和分子对接研究

期刊:Pharmacology Research & Perspectives
影响因子:2.3
doi:10.1002/prp2.70088
Lolak, Nebih; Akocak, Suleyman; Topal, Meryem; Koçyiğit, Ümit Muhammet; Işık, Mesut; Türkeş, Cüneyt; Topal, Fevzi; Durgun, Mustafa; Beydemir, Şükrü
发表日期：2025
文献求助 收藏

Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases

磺酰胺席夫碱的合成、表征、生物评价及计算机模拟研究

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.6
doi:10.1080/14756366.2020.1746784
Mustafa Durgun, Cüneyt Türkeş, Mesut Işık, Yeliz Demir, Ali Saklı, Ali Kuru, Abdussamat Güzel, Şükrü Beydemir, Suleyman Akocak, Sameh M Osman, Zeid AlOthman, Claudiu T Supuran
信号转导
发表日期：2020
文献求助 收藏

Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile

含有 1,3,5-三嗪结构基序的磺胺类药物具有抗氧化、乙酰胆碱酯酶、丁酰胆碱酯酶和酪氨酸酶抑制作用

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.6
doi:10.1080/14756366.2019.1707196
Nabih Lolak, Mehmet Boga, Muhammed Tuneg, Gulcin Karakoc, Suleyman Akocak, Claudiu T Supuran
信号转导
发表日期：2020
文献求助 收藏

Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action

合成具有抗氧化、抑制乙酰胆碱酯酶、丁酰胆碱酯酶、酪氨酸酶和碳酸酐酶活性的杯[4]氮杂冠醚取代磺酰胺

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2020.1765166
Oguz, Mehmet; Kalay, Erbay; Akocak, Suleyman; Nocentini, Alessio; Lolak, Nebih; Boga, Mehmet; Yilmaz, Mustafa; Supuran, Claudiu T
发表日期：2020
文献求助 收藏

Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII

3-氨基苯磺酰胺的吡啶衍生物是肿瘤表达的碳酸酐酶同工酶 CA IX 和 CA XII 的纳摩尔强效抑制剂

期刊:Bioorganic Chemistry
影响因子:4.5
doi:10.1016/j.bioorg.2020.104204
Suleyman Akocak, Özlen Güzel-Akdemir, Rajesh Kishore Kumar Sanku, Samson S Russom, Bogdan I Iorga, Claudiu T Supuran, Marc A Ilies
肿瘤
发表日期：2020
文献求助 收藏

Synthesis and cytotoxic activities of novel copper and silver complexes of 1,3-diaryltriazene-substituted sulfonamides

1,3-二芳基三氮烯取代磺酰胺新型铜和银配合物的合成及细胞毒活性

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.6
doi:10.1080/14756366.2018.1530994
Dilek Canakci, Ismail Koyuncu, Nabih Lolak, Mustafa Durgun, Suleyman Akocak, Claudiu T Supuran
免疫
细胞生物学
其它细胞
发表日期：2019
文献求助 收藏