Akshay Bhinge相关文献与解析，生知库 | 链接生命科学的每一步

Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis

miR-139 缺失导致 β-catenin 上调，导致肌萎缩侧索硬化症中的运动神经元死亡

doi:10.1016/j.stemcr.2022.05.019

Sophie Hawkins, Seema C Namboori, Ammarah Tariq, Catherine Blaker, Christine Flaxman, Nidhi S Dey, Peter Henley, Andrew Randall, Alessandro Rosa, Lawrence W Stanton, Akshay Bhinge

Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons

单细胞转录组学识别 SOD1 ALS iPSC 衍生运动神经元中神经变性的主要调节因子

期刊:Stem Cell Reports

影响因子:5.9

doi:10.1016/j.stemcr.2021.10.010

Seema C Namboori, Patricia Thomas, Ryan Ames, Sophie Hawkins, Lawrence O Garrett, Craig R G Willis, Alessandro Rosa, Lawrence W Stanton, Akshay Bhinge

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

单细胞基因表达分析揭示了发育中人类神经元中不同细胞亚群的调控因子

期刊:Genome Research

影响因子:6.2

doi:10.1101/gr.223313.117

Jiaxu Wang ,Piroon Jenjaroenpun ,Akshay Bhinge ,Vladimir Espinosa Angarica ,Antonio Del Sol ,Intawat Nookaew ,Vladimir A Kuznetsov ,Lawrence W Stanton

Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis

SOD1 突变 iPSC 的基因校正表明 ERK 和 JNK 激活的 AP1 是肌萎缩侧索硬化症中神经退行性疾病的驱动因素

期刊:Stem Cell Reports

影响因子:5.9

doi:10.1016/j.stemcr.2017.02.019

Akshay Bhinge, Seema C Namboori, Xiaoyu Zhang, Antonius M J VanDongen, Lawrence W Stanton

Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis

Sox2 第 39 位丝氨酸的细胞周期蛋白依赖性激酶依赖性磷酸化调节神经发生

期刊:Molecular and Cellular Biology

影响因子:3.2

doi:10.1128/MCB.00201-17

Shuhui Lim, Akshay Bhinge, Sara Bragado Alonso, Irene Aksoy, Julieta Aprea, Chit Fang Cheok, Federico Calegari, Lawrence W Stanton, Philipp Kaldis

ePRINT: exonuclease assisted mapping of protein-RNA interactions

ePRINT：外切酶辅助绘制蛋白质-RNA相互作用图谱

WNT7A-positive dendritic cytonemes control synaptogenesis in cortical neurons

WNT7A 阳性树突状细胞控制皮质神经元的突触形成

Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis

miR-139 缺失导致 β-catenin 上调，导致肌萎缩侧索硬化症中的运动神经元死亡

Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons

单细胞转录组学识别 SOD1 ALS iPSC 衍生运动神经元中神经变性的主要调节因子

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

单细胞基因表达分析揭示了发育中人类神经元中不同细胞亚群的调控因子

Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis

SOD1 突变 iPSC 的基因校正表明 ERK 和 JNK 激活的 AP1 是肌萎缩侧索硬化症中神经退行性疾病的驱动因素

Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis

Sox2 第 39 位丝氨酸的细胞周期蛋白依赖性激酶依赖性磷酸化调节神经发生