Akula Hari K相关文献与解析，生知库 | 链接生命科学的每一步

Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection.

氟-18和氘标记的L-氟丙氨酸作为正电子发射断层扫描成像剂在癌症检测中的合成和生物学评价

doi:10.1021/acs.jmedchem.4c00774

Li Kaixuan, Gilberti Alexa L, Marden Jocelyn A, Akula Hari K, Pollard Alyssa C, Guo Shuwen, Hu Bao, Tonge Peter J, Qu Wenchao

肿瘤

发表日期：2024

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Preclinical Positron Emission Tomography (PET) of Prosthetic Joint Infection Using a Nitro-Prodrug of 2-[(18)F]F-p-Aminobenzoic Acid ([(18)F]F-PABA)

使用 2-[(18)F]Fp-氨基苯甲酸 ([(18)F]F-PABA) 硝基前药进行假体关节感染的临床前正电子发射断层扫描 (PET)

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.4c00075

Pollard-Kerning, Alyssa C; Li, Kaixuan; Li, Yong; Ahn, Shin Hye; Wang, Mingqian; Akoglu, Melike; Bravo, Eduardo; DelloRusso, Francesca; Akula, Hari K; Qu, Wenchao; Meimetis, Labros; Schlyer, David J; Komatsu, David E; Tonge, Peter J

炎症/感染

发表日期：2024

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The potential utility of (2S,4R)-4-[18F] fluoroglutamine as a novel metabolic imaging marker for inflammation explored by rat models of arthritis and paw edema

利用大鼠关节炎和爪水肿模型，探讨了(2S,4R)-4-[18F]氟谷氨酰胺作为一种新型炎症代谢成像标志物的潜在应用价值。

期刊:

影响因子:

doi:10.21203/rs.3.rs-4493375/v1

Min-Jeong, Kim; Akula, Hari K; Marden, Jocelyn; Li, Kaixuan; Hu, Bao; Vaska, Paul; Qu, Wenchao

An improved synthesis of [(18) F]VAT and its precursor

改进的[(18)F]VAT及其前体的合成方法

期刊:Journal of Labelled Compounds & Radiopharmaceuticals

影响因子:0.9

doi:10.1002/jlcr.4059

Hu, Bao; Akula, Hari K; Noh, Doyoung; Mui, Yiu Fung; Slifstein, Mark; Parsey, Ramin; Qu, Wenchao

发表日期：2023

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Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine

无需外加氢气的催化还原：四羟基二硼与叔胺的广谱氢化反应

期刊:Advanced Synthesis & Catalysis

影响因子:4

doi:10.1002/adsc.201901099

Korvinson, Kirill A; Akula, Hari K; Malinchak, Casina T; Sebastian, Dellamol; Wei, Wei; Khandaker, Tashrique A; Andrzejewska, Magdalena R; Zajc, Barbara; Lakshman, Mahesh K

发表日期：2020

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Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate

利用1H-苯并三唑-1-氧基-三(二甲基氨基)六氟磷酸鏻进行原位酰胺活化，可轻松修饰嘧啶核苷的C4位。

期刊:Current Protocols in Nucleic Acid Chemistry

影响因子:

doi:10.1002/cpnc.73

Akula, Hari K; Lakshman, Mahesh K

发表日期：2019

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Ruthenium-Catalyzed C-H Bond Activation Approach to Azolyl Aminals and Hemiaminal Ethers, Mechanistic Evaluations, and Isomer Interconversion

钌催化CH键活化法合成唑基氨基缩醛和半缩醛醚，机理评价及异构体相互转化

期刊:ACS Catalysis

影响因子:13.1

doi:10.1021/acscatal.5b02603

Singh, Manish K; Akula, Hari K; Satishkumar, Sakilam; Stahl, Lothar; Lakshman, Mahesh K

发表日期：2016

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Mild and General Access to Diverse 1H-Benzotriazoles via Diboron-Mediated N-OH Deoxygenation and Palladium-Catalyzed C-C and C-N Bond Formation

通过二硼介导的N-OH脱氧和钯催化的CC和CN键形成，温和且通用地合成多种1H-苯并三唑

期刊:Advanced Synthesis & Catalysis

影响因子:4

doi:10.1002/adsc.201400889

Gurram, Venkateshwarlu; Akula, Hari K; Garlapati, Ramesh; Pottabathini, Narender; Lakshman, Mahesh K

发表日期：2015

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Deuterium- and Fluorine-18-Labeled Glutamineî¸a PET Imaging Agent with Enhanced In Vivo Stability.

氘和氟-18标记的谷氨酰胺——一种具有增强体内稳定性的PET成像剂

Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection.

氟-18和氘标记的L-氟丙氨酸作为正电子发射断层扫描成像剂在癌症检测中的合成和生物学评价

Preclinical Positron Emission Tomography (PET) of Prosthetic Joint Infection Using a Nitro-Prodrug of 2-[(18)F]F-p-Aminobenzoic Acid ([(18)F]F-PABA)

使用 2-[(18)F]Fp-氨基苯甲酸 ([(18)F]F-PABA) 硝基前药进行假体关节感染的临床前正电子发射断层扫描 (PET)

The potential utility of (2S,4R)-4-[18F] fluoroglutamine as a novel metabolic imaging marker for inflammation explored by rat models of arthritis and paw edema

利用大鼠关节炎和爪水肿模型，探讨了(2S,4R)-4-[18F]氟谷氨酰胺作为一种新型炎症代谢成像标志物的潜在应用价值。

An improved synthesis of [(18) F]VAT and its precursor

改进的[(18)F]VAT及其前体的合成方法

Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine

无需外加氢气的催化还原：四羟基二硼与叔胺的广谱氢化反应

Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate

利用1H-苯并三唑-1-氧基-三(二甲基氨基)六氟磷酸鏻进行原位酰胺活化，可轻松修饰嘧啶核苷的C4位。

Ruthenium-Catalyzed C-H Bond Activation Approach to Azolyl Aminals and Hemiaminal Ethers, Mechanistic Evaluations, and Isomer Interconversion

钌催化CH键活化法合成唑基氨基缩醛和半缩醛醚，机理评价及异构体相互转化

Mild and General Access to Diverse 1H-Benzotriazoles via Diboron-Mediated N-OH Deoxygenation and Palladium-Catalyzed C-C and C-N Bond Formation

通过二硼介导的N-OH脱氧和钯催化的CC和CN键形成，温和且通用地合成多种1H-苯并三唑

Deuterium- and Fluorine-18-Labeled Glutamineî¸a PET Imaging Agent with Enhanced In Vivo Stability.

氘和氟-18标记的谷氨酰胺——一种具有增强体内稳定性的PET成像剂

Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection.

氟-18和氘标记的L-氟丙氨酸作为正电子发射断层扫描成像剂在癌症检测中的合成和生物学评价

Preclinical Positron Emission Tomography (PET) of Prosthetic Joint Infection Using a Nitro-Prodrug of 2-[(18)F]F-p-Aminobenzoic Acid ([(18)F]F-PABA)

使用 2-[(18)F]Fp-氨基苯甲酸 ([(18)F]F-PABA) 硝基前药进行假体关节感染的临床前正电子发射断层扫描 (PET)

The potential utility of (2S,4R)-4-[18F] fluoroglutamine as a novel metabolic imaging marker for inflammation explored by rat models of arthritis and paw edema

利用大鼠关节炎和爪水肿模型，探讨了(2S,4R)-4-[18F]氟谷氨酰胺作为一种新型炎症代谢成像标志物的潜在应用价值。

An improved synthesis of [(18) F]VAT and its precursor

改进的[(18)F]VAT及其前体的合成方法

Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine

无需外加氢气的催化还原：四羟基二硼与叔胺的广谱氢化反应

Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate

利用1H-苯并三唑-1-氧基-三(二甲基氨基)六氟磷酸鏻进行原位酰胺活化，可轻松修饰嘧啶核苷的C4位。

Ruthenium-Catalyzed C-H Bond Activation Approach to Azolyl Aminals and Hemiaminal Ethers, Mechanistic Evaluations, and Isomer Interconversion

钌催化CH键活化法合成唑基氨基缩醛和半缩醛醚，机理评价及异构体相互转化

Mild and General Access to Diverse 1H-Benzotriazoles via Diboron-Mediated N-OH Deoxygenation and Palladium-Catalyzed C-C and C-N Bond Formation

通过二硼介导的N-OH脱氧和钯催化的CC和CN键形成，温和且通用地合成多种1H-苯并三唑

Deuterium- and Fluorine-18-Labeled Glutamineî¸a PET Imaging Agent with Enhanced In Vivo Stability.