日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus.

外排泵和膜通透性是脓肿分枝杆菌产生固有抗生素耐药性的原因

McGowen Kerry, Funck Tobias, Wang Xin, Zinga Samuel, Wolf Ian D, Akusobi Chidiebere, Denkinger Claudia M, Rubin Eric J, Sullivan Mark R

Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains

对多个脓肿分枝杆菌分离株进行转座子测序,揭示了菌株间显著的功能基因组多样性。

Akusobi, Chidiebere; Choudhery, Sanjeevani; Benghomari, Bouchra S; Wolf, Ian D; Singhvi, Shreya; Ioerger, Thomas R; Rubin, Eric J

Durlobactam in combination with β-lactams to combat Mycobacterium abscessus

Durlobactam 与 β-内酰胺类抗生素联合用于对抗脓肿分枝杆菌

Shin, Eunjeong; Dousa, Khalid M; Taracila, Magdalena A; Bethel, Christopher R; Nantongo, Mary; Nguyen, David C; Akusobi, Chidiebere; Kurz, Sebastian G; Plummer, Mark S; Daley, Charles L; Holland, Steven M; Rubin, Eric J; Bulitta, Jürgen B; Boom, W Henry; Kreiswirth, Barry N; Bonomo, Robert A

Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus

外排泵和膜通透性导致脓肿分枝杆菌产生内在抗生素耐药性

Kerry McGowen, Tobias Funck, Xin Wang, Samuel Zinga, Ian D Wolf, Chidiebere C Akusobi, Claudia M Denkinger, Eric J Rubin, Mark R Sullivan

Biotin-dependent cell envelope remodelling is required for Mycobacterium abscessus survival in lung infection

生物素依赖性细胞包膜重塑是脓肿分枝杆菌在肺部感染中存活的必要条件

Mark R Sullivan, Kerry McGowen, Qiang Liu, Chidiebere Akusobi, David C Young, Jacob A Mayfield, Sahadevan Raman, Ian D Wolf, D Branch Moody, Courtney C Aldrich, Alexander Muir, Eric J Rubin

Unusual prophages in Mycobacterium abscessus genomes and strain variations in phage susceptibilities

脓肿分枝杆菌基因组中不寻常的前噬菌体以及噬菌体敏感性的菌株差异

Amarh, Elizabeth D; Dedrick, Rebekah M; Garlena, Rebecca A; Russell, Daniel A; Gauthier, Christian H; Aull, Haley G; Abad, Lawrence; Jacobs-Sera, Deborah; Akusobi, Chidiebere; Rubin, Eric J; Hatfull, Graham F

Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity

脓肿分枝杆菌的转座子诱变鉴定出一种参与隔膜肽聚糖合成和抗生素敏感性的必需青霉素结合蛋白。

Akusobi, Chidiebere; Benghomari, Bouchra S; Zhu, Junhao; Wolf, Ian D; Singhvi, Shreya; Dulberger, Charles L; Ioerger, Thomas R; Rubin, Eric J

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

埃博拉病毒核蛋白寡聚化、病毒体样颗粒出芽和微基因组活性的报告基因检测揭示了核蛋白氨基酸位置 111 的重要性

Aaron E Lin, William E Diehl, Yingyun Cai, Courtney L Finch, Chidiebere Akusobi, Robert N Kirchdoerfer, Laura Bollinger, Stephen F Schaffner, Elizabeth A Brown, Erica Ollmann Saphire, Kristian G Andersen, Jens H Kuhn, Jeremy Luban, Pardis C Sabeti1

Parallel Evolution of Host-Attachment Proteins in Phage PP01 Populations Adapting to Escherichia coli O157:H7

噬菌体PP01群体适应大肠杆菌O157:H7的宿主附着蛋白的平行进化

Akusobi, Chidiebere; Chan, Benjamin K; Williams, Elizabeth S C P; Wertz, John E; Turner, Paul E

The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity

细菌III型毒素-抗毒素系统(ToxIN)是一种动态的蛋白质-RNA复合物,具有稳定性依赖性的抗病毒中止感染活性。

Short, Francesca L; Akusobi, Chidiebere; Broadhurst, William R; Salmond, George P C