日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Theoretical Survey of the Intrinsic Reactivity of Functionalized (CH(2)=C(R)XH) Enols, Enethiols and Eneselenols: Potential Interstellar Species

功能化(CH(2)=C(R)XH)烯醇、烯硫醇和烯硒醇的固有反应性的理论研究:潜在的星际物种

Lamsabhi, Al Mokhtar; Mó, Otilia; Guillemin, Jean-Claude; Yáñez, Manuel

Disrupting the KRAS-SOS1 protein-protein interaction: mechanistic rationale for pan-KRAS pathway suppression and combination therapy

破坏KRAS-SOS1蛋白-蛋白相互作用:泛KRAS通路抑制和联合治疗的机制原理

Kamel, Emadeldin M; Khadrawy, Sally Mostafa; Ali, Mohamed A M; Abukhadra, Mostafa R; Yassin, Nour Y S; Alkhedhairi, Saleh; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar

Disrupting the ASH2L-DPY30 PPI in cancer: structure, function, and therapeutic opportunities in H3K4 methylation

破坏癌症中的ASH2L-DPY30蛋白-蛋白质相互作用:H3K4甲基化中的结构、功能和治疗机会

Kamel, Emadeldin M; Allam, Ahmed A; Rudayni, Hassan A; Alkhedhairi, Saleh; Ahmed, Noha A; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar

Disarming the Hsp70-Bim Alliance: Small-Molecule and Peptidic Disruptors of a Chaperone-Apoptotic Switch in Cancer

解除 Hsp70-Bim 联盟的武装:癌症中分子伴侣-凋亡开关的小分子和肽类干扰剂

Kamel, Emadeldin M; Al-Zharani, Mohammed; Alneghery, Lina M; Ahmed, Noha A; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar

Multi-pronged molecular insights into flavonoid-mediated inhibition of squalene epoxidase: a pathway to novel therapeutics

从多方面深入研究类黄酮介导的角鲨烯环氧化酶抑制机制:一条通往新型疗法的途径

Kamel, Emadeldin M; Othman, Sarah I; Rudayni, Hassan A; Allam, Ahmed A; Lamsabhi, Al Mokhtar

Correction: Multi-pronged molecular insights into flavonoid-mediated inhibition of squalene epoxidase: a pathway to novel therapeutics

更正:多管齐下的分子机制揭示黄酮类化合物介导的角鲨烯环氧化酶抑制作用:一条通往新型疗法的途径

Kamel, Emadeldin M; Othman, Sarah I; Rudayni, Hassan A; Allam, Ahmed A; Lamsabhi, Al Mokhtar

Disrupting the Hsp90-Cdc37 axis: a selective strategy for targeting oncogenic kinases in cancer

破坏Hsp90-Cdc37轴:一种选择性靶向癌症致癌激酶的策略

Kamel, Emadeldin M; Ali, Mohamed A M; Allam, Ahmed A; Ahmed, Noha A; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar

Sustainable leads for hypoxic tumor therapy: allosteric selective inhibition of carbonic anhydrase IX by abietane-type resin acids

乏氧肿瘤治疗的可持续线索:枞烷型树脂酸对碳酸酐酶IX的变构选择性抑制

Kamel, Emadeldin M; Osman, Ali H M; Othman, Sarah I; Abalkhail, Adil; Maodaa, Saleh; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar

Breaking the oncogenic alliance: advances in disrupting the MTDH-SND1 complex for cancer therapy

打破致癌联盟:破坏 MTDH-SND1 复合物用于癌症治疗的进展

Ahmed, Noha A; Allam, Ahmed A; Rudayni, Hassan A; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar; Kamel, Emadeldin M

Entrance-channel plugging by natural sulfonamide antibiotics yields isoform-selective carbonic anhydrase IX inhibitors: an integrated in silico/ in vitro discovery of the lead SB-203207

天然磺胺类抗生素通过堵塞入口通道产生同工型选择性碳酸酐酶IX抑制剂:先导化合物SB-203207的计算机辅助/体外整合发现

Kamel, Emadeldin M; Ahmed, Noha A; Maodaa, Saleh; Abuamarah, Bassam A; Othman, Sarah I; Abalkhail, Adil; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar