Al-Mossawi Hussein相关文献与解析，生知库

Becker, Matthew W; Brown, Matthew E; Wiseman, Katherine; Chiodetti, Ana Laura; Huber, Mollie K; Cuaycal, Alexandra E; Sintara, Pumin; Ferreira, Sandra M; Smurlick, Dylan; Barra, Jessie M; Ladd, Andrew M; Drotar, Denise M; Atkinson, Mark A; Weber, Peter; Al-Mossawi, Hussein; Russ, Holger A; Mahon, Tara M; Brusko, Todd M; Bossi, Giovanna; Phelps, Edward A

细胞生物学

PD-1

免疫/内分泌

发表日期：2026

文献求助收藏

Metabolomic profiling of patients with lupus nephritis reveals unique metabolites that are modulated through type I interferon inhibition by anifrolumab treatment in a phase 2 trial

在一项二期临床试验中，对狼疮性肾炎患者进行代谢组学分析发现，阿尼弗鲁单抗治疗可通过抑制I型干扰素来调节独特的代谢物。

期刊:RMD Open

影响因子:4.7

doi:10.1136/rmdopen-2025-005932

Gavin, Patrick G; Allman, Erik L; Jayne, David; Mysler, Eduardo; Amoura, Zahir; Di Poto, Cristina; Tian, Xiang; Hess, Sonja; Csomor, Eszter; Brohawn, Philip Z; Muthas, Daniel; Platt, Adam; Anzillotti, Consuelo; Stone, Heena; Seth, Asha; Woollard, Kevin; Al-Mossawi, Hussein; Lindholm, Catharina; Ferrari, Nicola

Liver fibro-inflammation in psoriatic arthritis with MASLD improved by anti-IL-17 treatment: a clinical case

抗IL-17治疗改善伴有MASLD的银屑病关节炎患者的肝脏纤维炎症：一例临床病例报告

期刊:Rheumatology

影响因子:4.4

doi:10.1093/rheumatology/keaf177

James, Lija; Pansini, Michele; Diamond, Charlie; Al-Mossawi, Hussein; Banerjee, Rajarshi; Thomaides-Brears, Helena; Coates, Laura C

High prevalence of MASLD in psoriasis and psoriatic arthritis assessed with multiparametric magnetic resonance imaging

多参数磁共振成像评估显示，银屑病和银屑病关节炎患者中MASLD患病率较高

期刊:Rheumatology

影响因子:4.4

doi:10.1093/rheumatology/keaf344

James, Lija; Diamond, Charlie; Al-Mossawi, Hussein; Andersson, Anneli; Pandya, Prashant; Shumbayawonda, Elizabeth; Izadi Firouzabadi, Leila; Watson, Lily; Savage, Laura J; Thomaides-Brears, Helena; Banerjee, Rajarshi; Coates, Laura C

Inhibition of cell-mediated immunity in type 1 diabetes by beta cell-targeted PD-1 agonists in pancreas tissue slices

胰腺组织切片中β细胞靶向PD-1激动剂对1型糖尿病细胞介导免疫的抑制作用

期刊:

影响因子:

doi:10.1101/2025.10.21.683528

Becker, Matthew W; Brown, Matthew; Wiseman, Katherine; Chiodetti, Ana Laura; Huber, Mollie K; Cuaycal, Alexandra E; Sintara, Pumin; Ferreira, Sandra M; Smurlick, Dylan; Barra, Jessie M; Ladd, Andrew M; Drotar, Denise M; Atkinson, Mark A; Weber, Peter; Al-Mossawi, Hussein; Russ, Holger A; Mahon, Tara M; Brusko, Todd M; Bossi, Giovanna; Phelps, Edward A

Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of two phase 3 trials

在两项 3 期临床试验中，基因表达和蛋白质组学分析表明，使用阿尼弗鲁单抗阻断 I 型干扰素可调节系统性红斑狼疮患者的关键免疫病理通路。

期刊:Annals of the Rheumatic Diseases

影响因子:20.6

doi:10.1136/ard-2023-225445

Baker, Tina; Sharifian, Hoda; Newcombe, Paul J; Gavin, Patrick G; Lazarus, Mark N; Ramaswamy, Madhu; White, Wendy I; Ferrari, Nicola; Muthas, Daniel; Tummala, Raj; Morand, Eric F; Furie, Richard A; Vital, Edward M; Chamberlain, Chris; Platt, Adam; Al-Mossawi, Hussein; Brohawn, Philip Z; Csomor, Eszter

Chimeric antigens displaying GPR65 extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor

在可溶性支架上展示 GPR65 胞外环的嵌合抗原，使得人们能够发现识别天然受体的抗体。

期刊:Bioengineered

影响因子:4.2

doi:10.1080/21655979.2023.2299522

Barrett, Janine; Leysen, Seppe; Galmiche, Cécile; Al-Mossawi, Hussein; Bowness, Paul; Edwards, Thomas E; Lawson, Alastair D G

信号转导

发表日期：2024

文献求助收藏

Correction: Targeting DORIS Remission and LLDAS in SLE: A Review

更正：针对系统性红斑狼疮的DORIS缓解和LLDAS：一项综述

期刊:Rheumatology and Therapy

影响因子:2.9

doi:10.1007/s40744-024-00679-w

Parra Sánchez, Agner R; van Vollenhoven, Ronald F; Morand, Eric F; Bruce, Ian N; Kandane-Rathnayake, Rangi; Weiss, Gudrun; Tummala, Raj; Al-Mossawi, Hussein; Sorrentino, Alessandro

A Randomized, Placebo-Controlled Phase III Extension Trial of the Long-Term Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus

一项随机、安慰剂对照的III期扩展试验，旨在评估Anifrolumab在活动性系统性红斑狼疮中的长期安全性和耐受性

期刊:Arthritis & Rheumatology

影响因子:10.9

doi:10.1002/art.42392

Kalunian, Kenneth C; Furie, Richard; Morand, Eric F; Bruce, Ian N; Manzi, Susan; Tanaka, Yoshiya; Winthrop, Kevin; Hupka, Ihor; Zhang, Lijin Jinny; Werther, Shanti; Abreu, Gabriel; Hultquist, Micki; Tummala, Raj; Lindholm, Catharina; Al-Mossawi, Hussein

Targeting DORIS Remission and LLDAS in SLE: A Review

针对系统性红斑狼疮的DORIS缓解和LLDAS靶向治疗：一项综述

期刊:Rheumatology and Therapy

影响因子:2.9

doi:10.1007/s40744-023-00601-w

Parra Sánchez, Agner R; van Vollenhoven, Ronald F; Morand, Eric F; Bruce, Ian N; Kandane-Rathnayake, Rangi; Weiss, Gudrun; Tummala, Raj; Al-Mossawi, Hussein; Sorrentino, Alessandro

Beta cell-targeted PD-1 agonist inhibits cell-mediated autoimmunity in pancreas tissue slices

靶向β细胞的PD-1激动剂抑制胰腺组织切片中的细胞介导的自身免疫

Metabolomic profiling of patients with lupus nephritis reveals unique metabolites that are modulated through type I interferon inhibition by anifrolumab treatment in a phase 2 trial

在一项二期临床试验中，对狼疮性肾炎患者进行代谢组学分析发现，阿尼弗鲁单抗治疗可通过抑制I型干扰素来调节独特的代谢物。

Liver fibro-inflammation in psoriatic arthritis with MASLD improved by anti-IL-17 treatment: a clinical case

抗IL-17治疗改善伴有MASLD的银屑病关节炎患者的肝脏纤维炎症：一例临床病例报告

High prevalence of MASLD in psoriasis and psoriatic arthritis assessed with multiparametric magnetic resonance imaging

多参数磁共振成像评估显示，银屑病和银屑病关节炎患者中MASLD患病率较高

Inhibition of cell-mediated immunity in type 1 diabetes by beta cell-targeted PD-1 agonists in pancreas tissue slices

胰腺组织切片中β细胞靶向PD-1激动剂对1型糖尿病细胞介导免疫的抑制作用

Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of two phase 3 trials

在两项 3 期临床试验中，基因表达和蛋白质组学分析表明，使用阿尼弗鲁单抗阻断 I 型干扰素可调节系统性红斑狼疮患者的关键免疫病理通路。

Chimeric antigens displaying GPR65 extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor

在可溶性支架上展示 GPR65 胞外环的嵌合抗原，使得人们能够发现识别天然受体的抗体。

Correction: Targeting DORIS Remission and LLDAS in SLE: A Review

更正：针对系统性红斑狼疮的DORIS缓解和LLDAS：一项综述

A Randomized, Placebo-Controlled Phase III Extension Trial of the Long-Term Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus

一项随机、安慰剂对照的III期扩展试验，旨在评估Anifrolumab在活动性系统性红斑狼疮中的长期安全性和耐受性

Targeting DORIS Remission and LLDAS in SLE: A Review

针对系统性红斑狼疮的DORIS缓解和LLDAS靶向治疗：一项综述