Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors
针对黑色素瘤的 MCL1 偏向释放了 BRAF 和 ERK1/2 通路抑制剂的凋亡潜力
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-019-12409-w
Matthew J Sale, Emma Minihane, Noel R Monks, Rebecca Gilley, Frances M Richards, Kevin P Schifferli, Courtney L Andersen, Emma J Davies, Mario Aladren Vicente, Eiko Ozono, Aleksandra Markovets, Jonathan R Dry, Lisa Drew, Vikki Flemington, Theresa Proia, Duncan I Jodrell, Paul D Smith, Simon J Cook
信号转导
肿瘤
黑色素瘤
IP
WB
Apoptosis
MAPK/ERK