日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PSMA antibody, humanized PSMA.CAR10.3, or Cetuximab increases prostate cancer localization of NF-κB p50-deficient immature myeloid cells (p50-IMC) and phagocytosis by their macrophage progeny

PSMA抗体、人源化PSMA.CAR10.3或西妥昔单抗可增加前列腺癌中NF-κB p50缺陷的未成熟髓系细胞(p50-IMC)的定位及其被巨噬细胞后代吞噬的作用。

Mohammad A Alzubi ,Theresa Barberi ,Alan D Friedman

Adoptive transfer of immature myeloid cells lacking NF-κB p50 (p50-IMC) impedes the growth of MHC-matched high-risk neuroblastoma

缺乏 NF-κB p50 (p50-IMC) 的未成熟髓系细胞的过继转移阻碍了 MHC 匹配的高危神经母细胞瘤的生长

Cheng Cui, Theresa Barberi, Rahul Suresh, Alan D Friedman

NF-κB p50-deficient immature myeloid cell (p50-IMC) adoptive transfer slows the growth of murine prostate and pancreatic ductal carcinoma

NF-κB p50缺陷型未成熟髓系细胞(p50-IMC)过继转移可减缓小鼠前列腺癌和胰腺导管癌的生长。

Rahul Suresh ,David J Barakat ,Theresa Barberi ,Lei Zheng ,Elizabeth Jaffee ,Kenneth J Pienta ,Alan D Friedman

C/EBPα induces Ebf1 gene expression in common lymphoid progenitors

C/EBPα诱导常见淋巴祖细胞中的Ebf1基因表达

Theresa Barberi, Cheng Cui, Alan D Friedman

Absence of host NF-κB p50 induces murine glioblastoma tumor regression, increases survival, and decreases T-cell induction of tumor-associated macrophage M2 polarization

宿主 NF-κB p50 的缺失会诱导小鼠胶质母细胞瘤肿瘤消退、增加存活率并降低 T 细胞诱导的肿瘤相关巨噬细胞 M2 极化

Theresa Barberi, Allison Martin, Rahul Suresh, David J Barakat, Sarah Harris-Bookman, Charles G Drake, Michael Lim, Alan D Friedman

Progression from the Common Lymphoid Progenitor to B/Myeloid PreproB and ProB Precursors during B Lymphopoiesis Requires C/EBPα

B淋巴细胞生成过程中,从共同淋巴祖细胞到B/髓系前B细胞和原B细胞的转化需要C/EBPα。

Hong Guo ,Theresa Barberi ,Rahul Suresh ,Alan D Friedman

Absence of myeloid Klf4 reduces prostate cancer growth with pro-atherosclerotic activation of tumor myeloid cells and infiltration of CD8 T cells

髓系 Klf4 的缺失会降低前列腺癌的生长,并导致肿瘤髓系细胞的促动脉粥样硬化激活和 CD8 T 细胞的浸润

David J Barakat, Rahul Suresh, Theresa Barberi, Kenneth J Pienta, Brian W Simons, Alan D Friedman

C/EBPβ regulates sensitivity to bortezomib in prostate cancer cells by inducing REDD1 and autophagosome-lysosome fusion

C/EBPβ通过诱导REDD1和自噬体-溶酶体融合调节前列腺癌细胞对硼替佐米的敏感性

David J Barakat, Janet Mendonca, Theresa Barberi, Jing Zhang, Sushant K Kachhap, Ido Paz-Priel, Alan D Friedman

Runx1 Phosphorylation by Src Increases Trans-activation via Augmented Stability, Reduced Histone Deacetylase (HDAC) Binding, and Increased DNA Affinity, and Activated Runx1 Favors Granulopoiesis

Src 对 Runx1 的磷酸化通过增强稳定性、降低组蛋白去乙酰化酶 (HDAC) 结合和增加 DNA 亲和力来增加反式激活,而激活的 Runx1 有利于粒细胞生成

Wan Yee Leong, Hong Guo, Ou Ma, Hui Huang, Alan B Cantor, Alan D Friedman

Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality

Tankyrase 抑制可促进人类幼稚多能状态的稳定,并改善功能

Ludovic Zimmerlin, Tea Soon Park, Jeffrey S Huo, Karan Verma, Sarshan R Pather, C Conover Talbot Jr, Jasmin Agarwal, Diana Steppan, Yang W Zhang, Michael Considine, Hong Guo, Xiufeng Zhong, Christian Gutierrez, Leslie Cope, M Valeria Canto-Soler, Alan D Friedman, Stephen B Baylin, Elias T Zambidis