日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma

AMV564(一种新型双价双特异性 CD33/CD3 T 细胞接合剂)在体外对 MDS 和黑色素瘤中的 MDSC 进行免疫耗竭

Pingyan Cheng, Xianghong Chen, Robert Dalton, Alexandra Calescibetta, Tina So, Danielle Gilvary, Grace Ward, Victoria Smith, Sterling Eckard, Judith A Fox, Jeanmarie Guenot, Joseph Markowitz, John L Cleveland, Kenneth L Wright, Alan F List, Sheng Wei, Erika A Eksioglu

Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS/STING/NLRP3 axis in myelodysplastic syndromes

体细胞基因突变导致细胞质 DNA 在骨髓增生异常综合征中影响 cGAS/STING/NLRP3 轴

Amy F McLemore, Hsin-An Hou, Benjamin S Meyer, Nghi B Lam, Grace A Ward, Amy L Aldrich, Matthew A Rodrigues, Alexis Vedder, Ling Zhang, Eric Padron, Nicole D Vincelette, David A Sallman, Omar Abdel-Wahab, Alan F List, Kathy L McGraw

Phase I Clinical Trial of Selinexor in Combination with Daunorubicin and Cytarabine in Previously Untreated Poor-Risk Acute Myeloid Leukemia

Selinexor 与柔红霉素和阿糖胞苷联合治疗未经治疗的高风险急性髓系白血病的 I 期临床试验

Kendra Sweet, Rami Komrokji, Eric Padron, Christopher L Cubitt, Joel G Turner, Junmin Zhou, Alan F List, David A Sallman, Jana L Dawson, Daniel M Sullivan, Julio Chavez, Bijal D Shah, Jeffrey E Lancet

S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes

S100A9 诱导的 PD-1/PD-L1 过度表达导致骨髓增生异常综合征中的造血功能低下

Pinyang Cheng, Erika A Eksioglu, Xianghong Chen, Wendy Kandell, Thu Le Trinh, Ling Cen, Jin Qi, David A Sallman, Yu Zhang, Nhan Tu, William A Adams, Chunze Zhang, Jinhong Liu, John L Cleveland, Alan F List, Sheng Wei

Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks

DOCK4 信号网络抑制剂可恢复骨髓增生异常综合征干细胞中 DOCK4 功能的丧失

Sriram Sundaravel, Wen-Liang Kuo, Jong Jin Jeong, Gaurav S Choudhary, Shanisha Gordon-Mitchell, Hui Liu, Tushar D Bhagat, Kathy L McGraw, Sandeep Gurbuxani, Alan F List, Amit Verma, Amittha Wickrema

Randomized Phase II Study of Azacitidine Alone or in Combination With Lenalidomide or With Vorinostat in Higher-Risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: North American Intergroup Study SWOG S1117

单独使用阿扎胞苷或与来那度胺或伏立诺他联合使用治疗高风险骨髓增生异常综合征和慢性粒单核细胞白血病的随机 II 期研究:北美组间研究 SWOG S1117

Mikkael A Sekeres, Megan Othus, Alan F List, Olatoyosi Odenike, Richard M Stone, Steven D Gore, Mark R Litzow, Rena Buckstein, Min Fang, Diane Roulston, Clara D Bloomfield, Anna Moseley, Aziz Nazha, Yanming Zhang, Mario R Velasco, Rakesh Gaur, Ehab Atallah, Eyal C Attar, Elina K Cook, Alyssa H Cull,

Lenalidomide induces lipid raft assembly to enhance erythropoietin receptor signaling in myelodysplastic syndrome progenitors

来那度胺诱导脂质筏组装以增强骨髓增生异常综合征祖细胞中的促红细胞生成素受体信号传导

Kathy L McGraw, Ashley A Basiorka, Joseph O Johnson, Justine Clark, Gisela Caceres, Eric Padron, Ruth Heaton, Yukiyasu Ozawa, Sheng Wei, Lubomir Sokol, Alan F List

GM-CSF-dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia

GM-CSF 依赖性 pSTAT5 敏感性是慢性粒单核细胞白血病具有治疗潜力的特征

Eric Padron, Jeffrey S Painter, Sateesh Kunigal, Adam W Mailloux, Kathy McGraw, Jessica M McDaniel, Eunhee Kim, Christopher Bebbington, Mark Baer, Geoffrey Yarranton, Jeffrey Lancet, Rami S Komrokji, Omar Abdel-Wahab, Alan F List, Pearlie K Epling-Burnette

Correlation of clinical response and response duration with miR-145 induction by lenalidomide in CD34(+) cells from patients with del(5q) myelodysplastic syndrome

del(5q) 骨髓增生异常综合征患者 CD34(+) 细胞中来那度胺诱导 miR-145 与临床反应和反应持续时间的相关性

Christopher P Venner, Joanna Wegrzyn Woltosz, Thomas J Nevill, H Joachim Deeg, Gisela Caceres, Uwe Platzbecker, Bart L Scott, Lubomir Sokol, Sandy Sung, Alan F List, Aly Karsan

JAK2-V617F-mediated signalling is dependent on lipid rafts and statins inhibit JAK2-V617F-dependent cell growth

JAK2-V617F 介导的信号传导依赖于脂质筏,他汀类药物抑制 JAK2-V617F 依赖的细胞生长

Lori N Griner, Kathy L McGraw, Joseph O Johnson, Alan F List, Gary W Reuther